- 関
- sulfite dehydrogenase、sulfite oxidase
WordNet
- an enzyme that catalyses the biochemical reduction of some specified substance
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/10/09 01:20:02」(JST)
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sulfite reductase |
Crystallographic structure of sulfite reductase from E. coli.[1]
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Identifiers |
EC number |
1.8.99.1 |
CAS number |
37256-51-2 |
Databases |
IntEnz |
IntEnz view |
BRENDA |
BRENDA entry |
ExPASy |
NiceZyme view |
KEGG |
KEGG entry |
MetaCyc |
metabolic pathway |
PRIAM |
profile |
PDB structures |
RCSB PDB PDBe PDBsum |
Gene Ontology |
AmiGO / EGO |
Search |
PMC |
articles |
PubMed |
articles |
NCBI |
proteins |
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Sulfite reductases (EC 1.8.99.1) are important enzymes in the process of sulfur metabolism.[2] They catalyze the reduction of sulfite to hydrogen sulfide and water.[2][3] Electrons for the reaction are provided by a dissociable molecule of either NADPH, bound flavins, or ferredoxins.[4]
- SO32− (sulfite) + electron donor H2S (hydrogen sulfide) + oxidized donor + 3 H2O
Sulfite reductases belong to the family of oxidoreductases, and are found in archaea, bacteria, fungi, and plants.[5] They are grouped as either assimilatory or dissimilatory sulfite reductases depending on their function, their spectroscopic properties, and their catalytic properties. This enzyme participates in selenoamino acid metabolism and sulfur assimilation. It employs two covalently coupled cofactors - an iron sulfur cluster and a siroheme - which deliver electrons to the substrate via this coupling.[6]
The systematic name of this enzyme class is hydrogen-sulfide:acceptor oxidoreductase. Other names in common use include assimilatory sulfite reductase, assimilatory-type sulfite reductase, and hydrogen-sulfide:(acceptor) oxidoreductase.
References
- ^ PDB: 1AOP; Crane BR, Siegel LM, Getzoff ED (October 1995). "Sulfite reductase structure at 1.6 Å: evolution and catalysis for reduction of inorganic anions". Science 270 (5233): 59–67. doi:10.1126/science.270.5233.59. PMID 7569952.
- ^ a b Parey K, Warkentin E, Kroneck PM, Ermler U (2010). "Reaction cycle of the dissimilatory sulfite reductase from Archaeoglobus fulgidus". Biochemistry 49 (41): 8912–8921. doi:10.1021/bi100781f. PMID 20822098.
- ^ Pinto R, Harrison JS, Hsu T, Jacobs WR, Leyh TS (September 2007). "Sulfite Reduction in Mycobacteria". J. Bacteriol. 189 (18): 6714–22. doi:10.1128/JB.00487-07. PMC 2045171. PMID 17644602.
- ^ Siegel LM, Murphy MJ, Kamin H (January 1973). "Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. I. The Escherichia coli hemoflavoprotein: molecular parameters and prosthetic groups". J. Biol. Chem. 248 (1): 251–64. PMID 4144254.
- ^ Schnell R, Sandalova T, Hellman U, Lindqvist Y, Schneider G (July 2005). "Siroheme- and [Fe4-S4]-dependent NirA from Mycobacterium tuberculosis is a sulfite reductase with a covalent Cys-Tyr bond in the active site". J. Biol. Chem. 280 (29): 27319–28. doi:10.1074/jbc.M502560200. PMID 15917234.
- ^ Crane BR, Getzoff ED (December 1996). "The relationship between structure and function for the sulfite reductases". Curr. Opin. Struct. Biol. 6 (6): 744–56. doi:10.1016/S0959-440X(96)80003-0. PMID 8994874.
Further reading
- Asada K (August 1967). "Purification and properties of a sulfite reductase from leaf tissue". J. Biol. Chem. 242 (16): 3646–54. PMID 6038492.
- Asada K, Tamura G, Bandurski RS (September 1969). "Methyl viologen-linked sulfite reductase from spinach leaves". J. Biol. Chem. 244 (18): 4904–15. PMID 5824566.
- Yoshimoto A, Nakamura T, Sato R (December 1967). "Isolation from Aspergillus nidulans, of a protein catalyzing the reduction of sulfite by reduced viologen dyes". J. Biochem. 62 (6): 756–66. PMID 5589532.
UpToDate Contents
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English Journal
- The role of extended Fe4S4 cluster ligands in mediating sulfite reductase hemoprotein activity.
- Cepeda MR1, McGarry L2, Pennington JM2, Krzystek J3, Elizabeth Stroupe M2.
- Biochimica et biophysica acta.Biochim Biophys Acta.2018 May 28. pii: S1570-9639(18)30080-3. doi: 10.1016/j.bbapap.2018.05.013. [Epub ahead of print]
- PMID 29852252
- Structure-Function Relationships in the Oligomeric NADPH-Dependent Assimilatory Sulfite Reductase.
- Askenasy I, Murray D, Andrews RM, Uversky VN, He H, Stroupe ME.
- Biochemistry.Biochemistry.2018 May 22. doi: 10.1021/acs.biochem.8b00446. [Epub ahead of print]
- The central step in the assimilation of sulfur is a six-electron reduction of sulfite to sulfide, catalyzed by the oxidoreductase NADPH-dependent assimilatory Sulfite Reductase (SiR). SiR is composed of two subunits. One is a multi-domain flavin-binding reductase (SiRFP) and the other an iron-contai
- PMID 29787249
- Sulfur partitioning between glutathione and protein synthesis determines plant growth.
- Speiser A1, Silbermann M1, Dong Y2, Haberland S1, Uslu VV3, Wang S1, Bangash SAK4, Reichelt M5, Meyer AJ6, Wirtz M7, Hell R8.
- Plant physiology.Plant Physiol.2018 May 11. pii: pp.00421.2018. doi: 10.1104/pp.18.00421. [Epub ahead of print]
- PMID 29752309
Japanese Journal
- Kinetic Assays for Determining In Vitro APS Reductase Activity in Plants without the Use of Radioactive Substances
- BRYCHKOVA Galina,YARMOLINSKY Dmitry,SAGI Moshe
- Plant and cell physiology 53(9), 1648-1658, 2012-09-01
- NAID 10031053664
- Techniques : Kinetic Assays for Determining In Vitro APS Reductase Activity in Plants without the Use of Radioactive Substances
- Brychkova Galina,Yarmolinsky Dmitry,Sagi Moshe
- Plant and Cell Physiology 53(9), 1648-1658, 2012-09
- NAID 40019417526
- A Novel In-Gel Assay and an Improved Kinetic Assay for Determining In Vitro Sulfite Reductase Activity in Plants
- BRYCHKOVA Galina,YARMOLINSKY Dmitry,VENTRUA Yvonne,SAGI Moshe
- Plant and cell physiology 53(8), 1507-1516, 2012-08-01
- NAID 10031052951
Related Links
- sul·fite re·duc·tase oxidoreductase catalyzing reduction of sulfite to H 2 S using some reduced acceptor. ... Searching for Genes and Proteins 1:30 Introduction 1:45 RECOMBINANT EXPRESSION OF SULFITE REDUCTASE FROM ...
- Dissimilatory Sulfite Reductase (Desulfoviridin) of the Taurine-Degrading, Non-Sulfate-Reducing Bacterium Bilophila wadsworthia RZATAU Contains a Fused DsrB ... Corresponding author. Mailing address: Fachbereich Biologie ...
★リンクテーブル★
[★]
- 英
- sulfite reductase
- 関
- 亜硫酸酸化酵素、亜硫酸レダクターゼ、亜硫酸脱水素酵素
[★]
亜硫酸脱水素酵素、亜硫酸デヒドロゲナーゼ
- 関
- sulfite oxidase、sulfite reductase
[★]
- 関
- sulfite dehydrogenase、sulfite reductase
[★]
- 英
- sulfite reductase
- 関
- 亜硫酸還元酵素
[★]
亜硫酸水素還元酵素、亜硫酸水素レダクターゼ、重亜硫酸還元酵素、重亜硫酸レダクターゼ
[★]
フェレドキシン依存性亜硫酸還元酵素、フェレドキシン依存性亜硫酸レダクターゼ
[★]
NADPH依存性亜硫酸還元酵素
[★]
- (酵素)還元酵素、レダクターゼ、リダクターゼ
- 関
- dehydrogenase、oxidase、oxidoreductase、reducing enzyme
[★]
亜硫酸、亜硫酸塩
- 関
- sulfurous、sulfurous acid