関: epithelioid sarcoma、sarcoma、soft tissue sarcoma

WordNet

small room in which a monk or nun lives (同)cubicle
a device that delivers an electric current as the result of a chemical reaction (同)electric cell
a room where a prisoner is kept (同)jail cell, prison cell
(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
any small compartment; "the cells of a honeycomb"
a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
any of various rotating shafts that serve as axes for larger rotating parts (同)mandrel, mandril, arbor
a piece of wood that has been turned on a lathe; used as a baluster, chair leg, etc.
a stick or pin used to twist the yarn in spinning
(biology) tiny fibers that are seen in cell division; the fibers radiate from two poles and meet at the equator in the middle; "chromosomes are distributed by spindles in mitosis and meiosis"
a usually malignant tumor arising from connective tissue (bone or muscle etc.); one of the four major types of cancer

PrepTutorEJDIC

(刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
錘(つむ),紡錘(ぼうすい)(紡いだ糸を巻き付ける両端の細くなった丸い棒) / (機械の)軸,心棒;支軸 / 細長くなる / …‘を'錘の形にする
肉腫(にくしゅ)
ひょろ長い

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/08/08 05:39:16」(JST)

wiki en

Spindle cell sarcoma is a type of connective tissue cancer in which the cells are spindle-shaped when examined under a microscope. The tumors generally begin in layers of connective tissue such as that under the skin, between muscles, and surrounding organs, and will generally start as a small lump with inflammation that grows. At first the lump will be self-contained as the tumor exists in its stage 1 state, and will not necessarily expand beyond its encapsulated form. However, it may develop cancerous processes that can only be detected through microscopic examination. As such, at this level the tumor is usually treated by excision that includes wide margins of healthy-looking tissue, followed by thorough biopsy and additional excision if necessary. The prognosis for a stage 1 tumor excision is usually fairly positive, but if the tumors progress to levels 2 and 3, prognosis is worse because tumor cells have likely spread to other locations. These locations can either be nearby tissues or system-wide locations that include the lungs, kidneys, and liver. In these cases prognosis is grim and chemotherapy and radiation are the only methods of controlling the cancer.

Spindle cell sarcoma can develop for a variety of reasons, including genetic predisposition but it also may be caused by a combination of other factors including injury and inflammation in patients that are already thought to be predisposed to such tumors. Spindle cells are a naturally occurring part of the body's response to injury. In response to an injury, infection, or other immune response the connective tissues will begin dividing to heal the affected area, and if the tissue is predisposed to spindle cell cancer the high cellular turnover may result in a few becoming cancerous and forming a tumor.

External links

Spindle cell sarcoma entry in the public domain NCI Dictionary of Cancer Terms

This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".

This oncology article is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

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1. 軟部組織肉腫の臨床所見、病理組織学的検査、診断的評価、および病期分類 clinical presentation histopathology diagnostic evaluation and staging of soft tissue sarcoma
2. 転移性軟部組織肉腫の全身治療 systemic treatment of metastatic soft tissue sarcoma
3. 四肢の軟部組織肉腫に対する補助化学療法および術前補助化学療法 adjuvant and neoadjuvant chemotherapy for soft tissue sarcoma of the extremities
4. 放射線関連肉腫 radiation associated sarcomas
5. 軟部および骨肉腫の病原因子 pathogenetic factors in soft tissue and bone sarcomas

English Journal

Malignant melanoma as second malignant neoplasm in long-term childhood cancer survivors: A systematic review.

Braam KI, Overbeek A, Kaspers GJ, Ronckers CM, Schouten-van Meeteren AY, Van Dulmen-Den Broeder E, Veening MA.SourceDivision of Oncology-Hematology, Department of Pediatrics, VU University Medical Center, Amsterdam, The Netherlands. katja.braam@vumc.nl.
Pediatric blood & cancer.Pediatr Blood Cancer.2012 May;58(5):665-74. doi: 10.1002/pbc.24023. Epub 2012 Jan 9.
This systematic review provides information on malignant melanoma as second malignant neoplasm (SMN) after childhood cancer and evaluates its risk factors. Study reports describing incidences of SMN and malignant melanoma as SMN in a population of childhood cancer survivors (CCS) were included. Of 1
PMID 22232079

Advanced atypical teratoid/rhabdoid tumor (ATRT) treated with intensive multimodal approach shows continued response to sarcoma type salvage therapy.

Subbiah V, Wolff J, Ketonen L, Ellezam B, Rytting ME.SourceDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas. vsubbiah@mdanderson.org.
Pediatric blood & cancer.Pediatr Blood Cancer.2012 May;58(5):823-4. doi: 10.1002/pbc.23322. Epub 2011 Sep 15.
PMID 21922648

Japanese Journal

肺肉腫との鑑別を要した肺炎症性筋線維芽細胞性腫瘍の1例

佐藤征二郎,保坂靖子,富樫賢一
日本呼吸器外科学会雑誌 = The journal of the Japanese Association for Chest Surgery 24(4), 770-775, 2010-05-15
肺炎症性筋線維芽細胞性腫瘍は稀な肺疾患であり，良性?低悪性度の腫瘍とされている．症例は23歳女性．健診の胸部X線にて異常陰影を指摘され当院紹介となった．胸部CTにて右肺S1領域に17mm大の境界明瞭，濃度均一な結節を認めた．術前気管支鏡検査にて肺肉腫を疑われ，手術を施行した．術中迅速肺組織診においても肺肉腫の診断であり，上葉切除リンパ節郭清を施行した．術後の病理診断では細胞密度の高い紡錘形細胞の増 …
NAID 10026475809

間葉芽腎腫の1例

堀米史子,藤原利男,土岡丘,岡本健太郎,金子恵,加藤広行
日本小児外科学会雑誌 46(1), 48-52, 2010-02-20
症例は生後3か月男児.富細胞型間葉芽腎腫cellular type mesoblastic nephroma (MN)の1例を報告する.哺乳不良を契機とし,長径約12cmの巨大な腹部腫瘤を認めた.腫瘍は乳白色充実性腫瘍でWilms腫瘍,腎明細胞肉腫との鑑別に難渋した.組織学的には,細胞密度の高い紡錘形細胞を主体とする腫瘍細胞が錯綜し,遺伝子検索にてETV6-NTRK3融合遺伝子RNAが検出され,臨 …
NAID 110007644567