Spinal stenosis is an abnormal narrowing of the spinal canal or neural foramen that results in pressure on the spinal cord or nerve roots.[6] Symptoms may include pain, numbness, or weakness in the arms or legs.[1] Symptoms are typically gradual in onset and improve with bending forwards.[1] Severe symptoms may include loss of bladder control, loss of bowel control, or sexual dysfunction.[1]
Causes may include osteoarthritis, rheumatoid arthritis, spinal tumors, trauma, Paget's disease of the bone, scoliosis, spondylolisthesis, and the genetic condition achondroplasia.[3] It can be classified by the part of the spine affected into cervical, thoracic, and lumbar stenosis.[2] Lumbar stenosis is the most common followed by cervical stenosis.[2] Diagnosis is generally based on symptoms and medical imaging.[4]
Treatment may involve medications, bracing, or surgery.[6] Medications may include NSAIDs, acetaminophen, or steroid injections.[7] Stretching and strengthening exercises may also be useful.[1] Limiting certain activities may be recommended.[6] Surgery is typically only done if other treatments are not effective, with the usual procedure being a decompressive laminectomy.[7]
Spinal stenosis occurs in as many as 8% of people.[4] It occurs most commonly in people over the age of 50.[8] Males and females are affected equally often.[9] The first modern description of the condition is from 1803 by Antoine Portal.[10] Evidence of the condition, however, dates back to Ancient Egypt.[10]
Contents
1Signs and symptoms
1.1Common
1.2Neurological disorders
2Causes
2.1Aging
2.2Arthritis
2.3Congenital
2.4Instability of the spine
2.5Trauma
2.6Tumors
3Types
4Diagnosis
4.1Medical history
4.2Physical examination
4.3MRI
4.4CT myelogram
4.5Red flags
5Treatments
5.1Non-surgical treatments
5.2Surgery
6Epidemiology
7References
8External links
Signs and symptoms
Drawing showing spinal stenosis with spinal cord compression
Common
Standing discomfort (94%)
Discomfort/pain, in shoulder, arm, hand (78%)
Bilateral symptoms (68%)
Numbness at or below the level of involvement (63%)
Weakness at or below the level of involvement (43%)
Pain or weakness in buttock / thigh only (8%)
Pain or weakness below the knee (3%)[11]
Neurological disorders
Cervical (spondylotic) myelopathy,[12] a syndrome caused by compression of the cervical spinal cord which is associated with "numb and clumsy hands", imbalance, loss of bladder and bowel control, and weakness that can progress to paralysis.
Pinched nerve,[13] causing numbness.
Intermittent neurogenic claudication[11][14][15] characterized by lower limb numbness, weakness, diffuse or radicular leg pain associated with paresthesia (bilaterally),[14] weakness and/or heaviness in buttocks radiating into lower extremities with walking or prolonged standing.[11] Symptoms occur with extension of spine and are relieved with spine flexion. Minimal to zero symptoms when seated or supine.[11]
A human vertebral column
Radiculopathy (with or without radicular pain)[14] neurologic condition—nerve root dysfunction causes objective signs such as weakness, loss of sensation and of reflex.
Cauda equina syndrome[16] - Lower extremity pain, weakness, numbness that may involve perineum and buttocks, associated with bladder and bowel dysfunction.
Lower back pain[11][15] due to degenerative disc or joint changes.[17][full citation needed]
Causes
Aging
Any of the factors below may cause the spaces in the spine to narrow.
Spinal ligaments can thicken (ligamenta flava)[18][19]
Bone spurs develop on the bone and into the spinal canal or foraminal openings
Intervertebral discs may bulge or herniate into the canal or foraminal openings[20]
Degenerative disc disease causes narrowing of the spaces [21]
Facet joints break down
Compression fractures of the spine, which are common in osteoporosis[22]
Cysts form on the facet joints causing compression of the spinal sac of nerves (thecal sac)
Arthritis
Osteoarthritis
Rheumatoid arthritis—much less common cause of spinal problems
Congenital
Spinal canal is too small at birth
Structural deformities of the vertebrae may cause narrowing of the spinal canal
Instability of the spine
A vertebra slips forward on another (spondylolisthesis)
Trauma
Accidents and injuries may dislocate the spine and the spinal canal or cause burst fractures that yield fragments of bone that go through the canal.[23]
Patients with cervical myelopathy caused by narrowing of the spinal canal are at higher risks of acute spinal cord injury if involved in accidents.[24]
Tumors
Irregular growths of soft tissue will cause inflammation.
Growth of tissue into the canal pressing on nerves, the sac of nerves, or the spinal cord.
Types
The most common forms are cervical spinal stenosis, which are at the level of the neck, and lumbar spinal stenosis, at the level of the lower back. Thoracic spinal stenosis, at the level of the mid-back, is much less common.[25]
In lumbar stenosis, the spinal nerve roots in the lower back are compressed which can lead to symptoms of sciatica (tingling, weakness, or numbness that radiates from the low back and into the buttocks and legs).
Cervical spinal stenosis can be far more dangerous by compressing the spinal cord. Cervical canal stenosis may lead to myelopathy, a serious condition causing symptoms including major body weakness and paralysis.[26] Such severe spinal stenosis symptoms are virtually absent in lumbar stenosis, however, as the spinal cord terminates at the top end of the adult lumbar spine, with only nerve roots (cauda equina) continuing further down.[27] Cervical spinal stenosis is a condition involving narrowing of the spinal canal at the level of the neck. It is frequently due to chronic degeneration,[28] but may also be congenital or traumatic. Treatment frequently is surgical.[28]
Diagnosis
Moderate to severe spinal stenosis at the levels of L3/4 and L4/5
The diagnosis of spinal stenosis involves a complete evaluation of the spine. The process usually begins with a medical history and physical examination. X-ray and MRI scans are typically used to determine the extent and location of the nerve compression.
Medical history
The medical history is the most important aspect of the examination as it will tell the physician about subjective symptoms, possible causes for spinal stenosis, and other possible causes of back pain.[29]
Physical examination
The physical examination of a patient with spinal stenosis will give the physician information about exactly where nerve compression is occurring. Some important factors that should be investigated are any areas of sensory abnormalities, numbness, irregular reflexes, and any muscular weakness.[29]
MRI
MRI has become the most frequently used study to diagnose spinal stenosis. The MRI uses electromagnetic signals to produce images of the spine. MRIs are helpful because they show more structures, including nerves, muscles, and ligaments, than seen on X-rays or CT scans. MRIs are helpful at showing exactly what is causing spinal nerve compression.
CT myelogram
A spinal tap is performed in the low back with dye injected into the spinal fluid. X-Rays are performed followed by a CT scan of the spine to help see narrowing of the spinal canal.
This is a very effective study in cases of lateral recess stenosis. It is also necessary for patients in which MRI is contraindicated, such as those with implanted pacemakers.
Red flags
Fever
Nocturnal pain
Gait disturbance
Structural deformity
Unexplained weight loss
Previous carcinoma
Severe pain upon lying down
Recent trauma with suspicious fracture
Presence of severe or progressive neurologic deficit[16]
Treatments
Treatment options are either surgical or non-surgical. Overall evidence is inconclusive whether non-surgical or surgical treatment is the better for lumbar spinal stenosis.[30]
Non-surgical treatments
The effectiveness of non surgical treatments is unclear as they have not been well studied.[31]
Education about the course of the condition and how to relieve symptoms
Medicines to relieve pain and inflammation, such as acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs)
Exercise, to maintain or achieve overall good health, aerobic exercise, such as riding a stationary bicycle, which allows for a forward lean, walking, or swimming can relieve symptoms
Weight loss, to relieve symptoms and slow progression of the stenosis
Physical therapy to support self-care.[32] Also may give instructs on stretching and strength exercises that may lead to a decrease in pain and other symptoms.
Lumbar epidural steroid or anesthetic injections have low quality evidence to support their use.[31][33][34]
Surgery
Lumbar decompressive laminectomy: This involves removing the roof of bone overlying the spinal canal and thickened ligaments in order to decompress the nerves and sac of nerves. 70-90% of people have good results.[35]
Interlaminar implant: This is a non-fusion U-shaped device which is placed between two bones in the lower back that maintains motion in the spine and keeps the spine stable after a lumbar decompressive surgery. The U-shaped device maintains height between the bones in the spine so nerves can exit freely and extend to lower extremities.[36]
Surgery for cervical myelopathy is either conducted from the front or from the back, depending on several factors such as where the compression occurs and how the cervical spine is aligned.
Anterior cervical discectomy and fusion: A surgical treatment of nerve root or spinal cord compression by decompressing the spinal cord and nerve roots of the cervical spine with a discectomy in order to stabilize the corresponding vertebrae.
Posterior approaches seek to generate space around the spinal cord by removing parts of the posterior elements of the spine. Techniques include laminectomy, laminectomy and fusion, and laminoplasty.
Epidemiology
The NAMCS data shows the incidence in the U.S. population to be 3.9% of 29,964,894 visits for mechanical back problems.[37]
The Longitudinal Framingham Heart Study found 1% of men and 1.5% of women had vertebral slippage at mean age of 54. Over the next 25 years, 11% of men and 25% of women developed degenerative vertebral slippage.[38]
References
^ abcdefg"Spinal Stenosis". National Institute of Arthritis and Musculoskeletal and Skin Diseases. 11 April 2017. Retrieved 19 December 2017.
^ abcCanale, S. Terry; Beaty, James H. (2012). Campbell's Operative Orthopaedics E-Book. Elsevier Health Sciences. p. 1994. ISBN 978-0323087186.
^ ab"Spinal Stenosis". National Institute of Arthritis and Musculoskeletal and Skin Diseases. 11 April 2017. Retrieved 19 December 2017.
^ abcdDomino, Frank J. (2010). The 5-Minute Clinical Consult 2011. Lippincott Williams & Wilkins. p. 1224. ISBN 9781608312597.
^Ferri, Fred F. (2017). Ferri's Clinical Advisor 2018 E-Book: 5 Books in 1. Elsevier Health Sciences. p. 1202. ISBN 9780323529570.
^ abcd"Spinal Stenosis". National Institute of Arthritis and Musculoskeletal and Skin Diseases. 11 April 2017. Retrieved 19 December 2017.
^ abc"Spinal Stenosis". National Institute of Arthritis and Musculoskeletal and Skin Diseases. 11 April 2017. Retrieved 19 December 2017.
^"Spinal Stenosis". National Institute of Arthritis and Musculoskeletal and Skin Diseases. 11 April 2017. Retrieved 19 December 2017.
^"Lumbar Spinal Stenosis". OrthoInfo - AAOS. December 2013. Retrieved 19 December 2017.
^ abBoos, Norbert; Aebi, Max (2008). Spinal Disorders: Fundamentals of Diagnosis and Treatment. Springer Science & Business Media. pp. 21–22. ISBN 9783540690917.
^ abcdeMazanec D. J.; Podichetty V. K.; Hsia A. (2002). "Lumbar Canal Stenosis: Start with nonsurgical therapy". Cleveland Clinic Journal of Medicine. 69 (11): 909–917. doi:10.3949/ccjm.69.11.909.
^"What is CSM?". Myelopathy.org. Retrieved 2015-11-23.
^"Cervical Radiculopathy (Pinched Nerve)". AAOS. Retrieved 13 December 2011.
^ abcCostantini A.; Buchser E.; Van Buyten J. P. (2009). "Spinal Cord Stimulation for the Treatment of Chronic Pain in Patients with Lumbar Spinal Stenosis". Neuromodulation. 13 (4): 275–380. doi:10.1111/j.1525-1403.2010.00289.x. PMID 21992882.
^ abGoren A.; Yildiz N.; Topuz O.; Findikoglu G.; Ardic F. (2010). "Efficacy of exercise and ultrasound in patients with lumbar spinal stenosis: A prospective randomized controlled trial". Clinical Rehabilitation. 24 (7): 623–631. doi:10.1177/0269215510367539. PMID 20530650.
^ abDoorly, T. P., Lambing, C. L., Malanga, G. A., Maurer, P. M., Ralph R., R. (2010). Algorithmic approach to the management of the patient with lumbar spinal stenosis. Journal of Family Practice, 59 S1-S8
^Mazanec, D. J., Podichetty, V. K., Hsia, A. (2002) Lumbar Clinic Journal of Medicine69 (11).
^Park JB, Lee JK, Park SJ, Riew KD, "Hypertrophy of ligamentum flavum in lumbar spinal stenosis associated with increased proteinase inhibitor concentration," J Bone Joint Surg Am. 2005 Dec;87(12):2750-7.
^ligamentum flavum, Physio-Pedia.com
^"Herniated Disk," Mayo-Clinic.org
^"Degenerative Disk Disease," Mayfieldclinic.com
^"Causes of Spinal Compression Fractures,", WebMD
^"Spinal stenosis Causes". Mayo Clinic. 2012-06-28. Retrieved 2015-04-17.
^Wu, Jau-Ching; Ko, Chin-Chu; Yen, Yu-Shu; Huang, Wen-Cheng; Chen, Yu-Chun; Liu, Laura; Tu, Tsung-Hsi; Lo, Su-Shun; Cheng, Henrich (2013-07-01). "Epidemiology of cervical spondylotic myelopathy and its risk of causing spinal cord injury: a national cohort study". Neurosurgical Focus. 35 (1): E10. doi:10.3171/2013.4.FOCUS13122. PMID 23815246.
^Vokshoor A (February 14, 2010). "Spinal Stenosis". eMedicine. Retrieved December 30, 2010.
^Manchikanti, L; Kaye, AD; Manchikanti, K; Boswell, M; Pampati, V; Hirsch, J (February 2015). "Efficacy of epidural injections in the treatment of lumbar central spinal stenosis: a systematic review". Anesthesiology and Pain Medicine. 5 (1): e23139. doi:10.5812/aapm.23139. PMC 4350165. PMID 25789241.
^Chou, R; Hashimoto, R; Friedly, J; Fu, R; Bougatsos, C; Dana, T; Sullivan, SD; Jarvik, J (25 August 2015). "Epidural Corticosteroid Injections for Radiculopathy and Spinal Stenosis: A Systematic Review and Meta-analysis". Annals of Internal Medicine. 163 (5): 373–81. doi:10.7326/M15-0934. PMID 26302454.
^Malamut, edited by Joseph I. Sirven, Barbara L. (2008). Clinical neurology of the older adult (2nd ed.). Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. p. 220. ISBN 9780781769471.CS1 maint: Extra text: authors list (link)
5. 成人における腰痛の評価 evaluation of low back pain in adults
English Journal
Epidural lysis of adhesions for failed back surgery and spinal stenosis: factors associated with treatment outcome.
Hsu E, Atanelov L, Plunkett AR, Chai N, Chen Y, Cohen SP.Author information From the *Department of Anesthesiology and Critical Care Medicine, Johns Hopkins School of Medicine; †Department of Physical Medicine & Rehabilitation, Johns Hopkins School of Medicine; ‡Department of Anesthesia & Operative Services, Womack Army Medical Center, Fort Bragg, North Carolina; §Department of Neurology, Johns Hopkins School of Medicine; ‖Johns Hopkins School of Medicine; ¶Departments of Anesthesiology and Critical Care Medicine & Physical Medicine and Rehabilitation; at Uniformed Services University of the Health Sciences.AbstractBACKGROUND: Failed back surgery syndrome (FBSS) is a challenging problem. One treatment advocated to treat FBSS is epidural lysis of adhesions (LOA). The results of studies examining LOA for FBSS have been mixed, but are limited because no study has ever sought to identify factors associated with outcomes.
Anesthesia and analgesia.Anesth Analg.2014 Jan;118(1):215-24. doi: 10.1213/ANE.0000000000000042.
BACKGROUND: Failed back surgery syndrome (FBSS) is a challenging problem. One treatment advocated to treat FBSS is epidural lysis of adhesions (LOA). The results of studies examining LOA for FBSS have been mixed, but are limited because no study has ever sought to identify factors associated with ou
Cervical radicular pain: the role of interlaminar and transforaminal epidural injections.
Manchikanti L, Falco FJ, Diwan S, Hirsch JA, Smith HS.Author information Pain Management Center of Paducah, 2831 Lone Oak Road, Paducah, KY, 42003, USA, drlm@thepainmd.com.AbstractChronic neck pain and cervical radicular pain are relatively common in the adult population. Treatment for chronic radicular pain recalcitrant to conservative management includes surgical management as well as interventional techniques with epidural injections utilizing either an interlaminar approach or transforaminal approach. Although there have been multiple systematic reviews and randomized clinical trials of cervical interlaminar epidural injections, the literature is sparse in reference to cervical transforaminal epidural injections. Overall, there is good evidence for the effectiveness of cervical interlaminar epidural injections in managing cervical disc herniation and fair evidence in managing central spinal stenosis and postsurgery syndrome. The evidence is poor, however, for cervical transforaminal epidural injections. Complications with cervical interlaminar epidural injections are rare, but more commonly occur with transforaminal epidural injections and can be fatal. Emerging concepts in pain include further randomized trials; proper placebo design; focus on control design (either active control or placebo control); and appropriate methodologic quality assessment and evidence synthesis.
Current pain and headache reports.Curr Pain Headache Rep.2014 Jan;18(1):389. doi: 10.1007/s11916-013-0389-9.
Chronic neck pain and cervical radicular pain are relatively common in the adult population. Treatment for chronic radicular pain recalcitrant to conservative management includes surgical management as well as interventional techniques with epidural injections utilizing either an interlaminar approa
Hecht JT1, Bodensteiner JB2, Butler IJ3.Author information 1Department of Pediatrics and Pediatric Research Center, University of Texas Medical School, Houston, TX, USA.2Department of Neurology, Mayo Clinic, Rochester, MN, USA.3Division of Child and Adolescent Neurology, Department of Pediatrics, University of Texas Medical School, Houston, TX, USA. Electronic address: ian.j.butler@uth.tmc.edu.AbstractAchondroplasia is the best described and most common form of the congenital short-limbed dwarfing conditions. Achondroplasia is apparent at birth and has a birth prevalence of 1 in 20000-30000 live-born infants. Achondroplasia is inherited as an autosomal dominant condition, although 80% of cases occur sporadically as new events in their families. Achondroplasia is caused, in virtually all of the cases, by a G380R mutation in fibroblast growth factor receptor 3 (FGFR3). Patients with achondroplasia should be evaluated by a multidisciplinary team of clinicians including geneticists, neurologists, and orthopedists, since there are numerous bony and neurological complications. The most severe complication results from craniocervical stenosis and medullary and upper spinal cord compression, which can have devastating and even lethal sequelae during early childhood. In subsequent decades, including adolescence, spinal cord and nerve compression are more prominent. The neurological complications of achondroplasia have been recognized in adults for more than a century and are attributed to bony defects, connective tissue structures, or both. Similar neurological complications are now appreciated in infants, young children, and teenagers with achondroplasia. Defective connective tissue elements in achondroplasia frequently lead to ligamentous laxity, which can aggravate the complications associated with bony stenosis. Bony abnormalities are known to cause neurological morbidity and lead to a shortened lifespan. Neurological complications associated with achondroplasia are reviewed, including recommendations for the evaluation and management of these clinical problems.
Handbook of clinical neurology.Handb Clin Neurol.2014;119:551-63. doi: 10.1016/B978-0-7020-4086-3.00036-9.
Achondroplasia is the best described and most common form of the congenital short-limbed dwarfing conditions. Achondroplasia is apparent at birth and has a birth prevalence of 1 in 20000-30000 live-born infants. Achondroplasia is inherited as an autosomal dominant condition, although 80% of cases oc
The spine, a row of 26 bones in your back, allows you to stand up straight and bend over. The spine also protects your spinal cord from being hurt. In people with spinal stenosis, the spine is narrowed in one or more of three parts: The ...
Spinal Stenosis The term ‘stenosis’ means narrowing of a tubular structure in the body. Spinal stenosis, then, means narrowing is in the spinal column, which houses the vertebrae, spinal cord, spinal discs, nerves and other tissues.