WordNet

a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11

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The chiral bioconversion and preclinical pharmacokinetic analysis of (R)-(+)-rabeprazole in beagle dogs by HPLC and HPLC-MS/MS.

Gao YH, Xu JX, Su ZX, Song L, Lou HX.SourceSchool of Pharmaceutical Sciences of Shandong University, No. 44 West Wenhua Road, Jinan, 250012, China.
Biomedical chromatography : BMC.Biomed Chromatogr.2013 May 22. doi: 10.1002/bmc.2932. [Epub ahead of print]
In order to accurately investigate the preclinical pharmacokinetics of (R)-(+)-rabeprazole sodium injection, a reliable high-performance liquid chromatography (HPLC) method was developed using a Chiral-AGP column to prove that there is no chiral bioconversion of (R)-(+)-rabeprazole to (S)-(-)-rabepr
PMID 23703236

Design and characterization of enteric-coated controlled release mucoadhesive microcapsules of Rabeprazole sodium.

Swain S, Behera UA, Beg S, Sruti J, Patro ChN, Dinda SC, Rao ME.SourceDepartment of Pharmaceutics, Roland Institute of Pharmaceutical Sciences , Khodasinghi, Berhampur-Gm, Odisha, India. swain_suryakant@yahoo.co.in
Drug development and industrial pharmacy.Drug Dev Ind Pharm.2013 Apr;39(4):548-60. doi: 10.3109/03639045.2012.676047. Epub 2012 Apr 18.
The objectives of present work was to design and characterize the rabeprazole sodium loaded microcapsules prepared by solvent evaporation technique using ethyl cellulose (EC) based various mucoadhesive polymer, followed by a triple coating with Eudragit L100. The Box-behnken design (BBD) was applied
PMID 22512732

Effect of the residual silanol group protection on the liquid chromatographic resolution of α-amino acids and proton pump inhibitors on a ligand exchange chiral stationary phase.

Ma DH, Jin JS, Jeong ED, Hyun MH.SourceDepartment of Chemistry and Chemistry Institute for Functional Materials, Pusan National University, Busan, South Korea.
Journal of separation science.J Sep Sci.2013 Apr;36(8):1349-55. doi: 10.1002/jssc.201300079. Epub 2013 Mar 20.
A new ligand exchange chiral stationary phase (new CSP) containing residual silanol group-protecting n-octyl groups on the silica surface was prepared by treating a ligand exchange CSP (original CSP) based on sodium N-[(R)-2-hydroxy-1-phenylethyl]-N-undecylaminoacetate bonded to silica gel with exce
PMID 23420568