sodium iodide

ヨウ化ナトリウム

関

NaI

WordNet

1. a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11
2. a salt or ester of hydriodic acid

PrepTutorEJDIC

1. ソジウム,ナトリウム(金属元素;化学記号はNa)
2. ヨウ化物

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/10/17 08:15:36」(JST)

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Sodium iodide
Identifiers
CAS number	7681-82-5 Y,  13517-06-1 (dihydrate)
PubChem	5238
ChemSpider	5048 Y
UNII	F5WR8N145C Y
ChEBI	CHEBI:33167 Y
ChEMBL	CHEMBL1644695 N
RTECS number	WB6475000
Jmol-3D images	Image 1
SMILES [Na+].[I-]
InChI InChI=1S/HI.Na/h1H;/q;+1/p-1 Y Key: FVAUCKIRQBBSSJ-UHFFFAOYSA-M Y InChI=1/HI.Na/h1H;/q;+1/p-1 Key: FVAUCKIRQBBSSJ-REWHXWOFAL
Properties
Molecular formula	NaI
Molar mass	149.89 g/mol
Appearance	white solid deliquescent
Odor	odorless
Density	3.67 g/cm3
Melting point	661 °C, 934 K, 1222 °F
Boiling point	1304 °C, 1577 K, 2379 °F
Solubility in water	178.8 g/100 mL (20 °C) 184 g/100 mL (25 °C) 294 g/100 mL (70 °C) 302 g/100 mL (100 °C)
Solubility	soluble in ethanol and acetone (39.9 g/100 mL)
Acidity (pKa)	8-9.5
Refractive index (nD)	1.7745
Structure
Coordination geometry	Octahedral
Thermochemistry
Std enthalpy of formation ΔfHo298	−288 kJ·mol−1
Standard molar entropy So298	91 J·mol−1·K−1
Hazards
MSDS	[1]
EU Index	Not listed
Main hazards	Irritant, can harm the unborn child
Flash point	Non-flammable
Related compounds
Other anions	Sodium fluoride Sodium chloride Sodium bromide
Other cations	Lithium iodide Potassium iodide Rubidium iodide Caesium iodide
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Sodium iodide is a white, crystalline salt with the chemical formula NaI, and is used in radiation detection, treatment of iodine deficiency, and as a reactant in the Finkelstein reaction.

Production

Sodium iodide is manufactured from the reaction between iodine and sodium hydroxide.

Uses

Food supplement

Sodium iodide, as well as potassium iodide, is commonly used to treat and prevent iodine deficiency. Iodized table salt contains one part sodium or potassium iodide to 100,000 parts of sodium chloride.

Organic synthesis

Sodium iodide is used in the Finkelstein reaction, for conversion of an alkyl chloride into an alkyl iodide. This method relies on the insolubility of sodium chloride in acetone to drive the reaction:

R-Cl + NaI → R-I + NaCl

Radiation physics and medicine

Sodium iodide activated with thallium, NaI(Tl), when subjected to ionizing radiation, emits photons (i.e., scintillate) and is used in scintillation detectors, traditionally in nuclear medicine, geophysics, nuclear physics, and environmental measurements. NaI(Tl) is the most widely used scintillation material. The crystals are usually coupled with a photomultiplier tube, in a hermetically sealed assembly, as sodium iodide is hygroscopic. Fine-tuning of some parameters (i.e., radiation hardness, afterglow, transparency) can be achieved by varying the conditions of the crystal growth. Crystals with a higher level of doping are used in X-ray detectors with high spectrometric quality. Sodium iodide can be used both as single crystals and as polycrystals for this purpose.

The radioactive iodide salt of sodium, Na¹³¹I, is used for the treatment of thyroid cancer and hyperthyroidism.

Solubility data

Solubility of NaI in various solvents
(g NaI / 100g of solvent at 25°C)

H2O	184
Liquid ammonia	162
Liquid sulfur dioxide	15
Methanol	62.5 - 83.0
Formic acid	61.8
Acetonitrile	24.9
Acetone	28.0
Formamide	57 - 85
Acetamide	32.3
Dimethylformamide	3.7 - 6.4

See also

• Gamma spectroscopy
• Scintillation counter
• Teratology

References

External links

• International Chemical Safety Card 1009 - Sodium Iodide (Anhydrous)
• Material Safety Data Sheet (MSDS) - Safety data for sodium iodide
• Sodium Iodide Consumer Information

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 放射性ヨウ素による甲状腺機能亢進症の治療 radioiodine in the treatment of hyperthyroidism
• 2. ヨード誘発性甲状腺機能異常症 iodine induced thyroid dysfunction
• 3. 分化型甲状腺癌：放射性ヨード治療 differentiated thyroid cancer radioiodine treatment
• 4. 胸部PET thoracic positron emission tomography
• 5. 甲状腺ホルモンの作用 thyroid hormone action

English Journal

• [(18)F]tetrafluoroborate as a PET tracer for the sodium/iodide symporter: the importance of specific activity.

• Khoshnevisan A1, Jauregui-Osoro M1, Shaw K1, Torres JB1, Young JD1, Ramakrishnan NK1, Jackson A2, Smith GE2, Gee AD1, Blower PJ3.
• EJNMMI research.EJNMMI Res.2016 Dec;6(1):34. doi: 10.1186/s13550-016-0188-5. Epub 2016 Apr 22.
• BACKGROUND: [(18)F]BF4 (-), the first (18)F-labelled PET imaging agent for the sodium/iodide symporter (NIS), was produced by isotopic exchange yielding a product with limited specific activity (SA, ca. 1 GBq/μmol) posing a risk of sub-optimal target-to-background ratios (TBR) in PET images due to
• PMID 27103614

• Methylated 4-N,N dimethyl aminobenzyl N,O carboxymethyl chitosan as a new chitosan derivative: Synthesis, characterization, cytotoxicity and antibacterial activity.

• Rahmani S1, Mohammadi Z2, Amini M3, Isaei E4, Taheritarigh S5, Rafiee Tehrani N6, Rafiee Tehrani M7.
• Carbohydrate polymers.Carbohydr Polym.2016 Sep 20;149:131-9. doi: 10.1016/j.carbpol.2016.04.116. Epub 2016 Apr 28.
• Chitosan, as a biocompatible polymer, is very attractive for biomedical applications. Continues studies are performing for improving its physicochemical features in order to make it more suitable for such approaches. In this study, methylated 4-N,N dimethyl aminobenzyl N,O carboxymethyl chitosan (MA
• PMID 27261738

• Development of a MSFIA system for sequential determination of antimony, arsenic and selenium using hydride generation atomic fluorescence spectrometry.

• de Santana FA1, Portugal LA2, Serra AM3, Ferrer L3, Cerdà V3, Ferreira SL4.
• Talanta.Talanta.2016 Aug 15;156-157:29-33. doi: 10.1016/j.talanta.2016.04.063. Epub 2016 Apr 30.
• This paper proposed a multisyringe flow injection analysis (MSFIA) system for antimony, arsenic and selenium determination in peanut samples by hydride generation atomic fluorescence spectrometry (HG-AFS). The optimization step of the hydride generation was performed using a two-level full factorial
• PMID 27260431

Japanese Journal

• Selective Spectrophotometric Determination of Trace Amounts of Cadmium in Soil and Sediment Samples Using a Green Aqueous Biphasic Extraction

• Analytical Sciences 32(10), 1095-1100, 2016
• NAID 130005249568

• 心臓専用半導体SPECT 装置における外部CT を用いた減弱補正法の効果

• 日本放射線技術学会雑誌 72(7), 610-616, 2016
• NAID 130005165504

• Follicular thyroglobulin enhances gene expression necessary for thyroid hormone secretion

• Endocrine Journal 62(11), 1007-1015, 2015
• NAID 130005109819

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★リンクテーブル★

リンク元	「ヨウ化ナトリウム」「NaI」
拡張検索	「sodium iodide(123I)」
関連記事	「iodide」

「ヨウ化ナトリウム」

　　[★]

英

sodium iodide, NaI

関

ヨウ化ナトリウム(123I)

「NaI」

　　[★]

• ヨウ化ナトリウム

関

sodium iodide

「sodium iodide(123I)」

　　[★] ヨウ化ナトリウム(123I)

「iodide」

　　[★]

• n.

• ヨウ化物、ヨウ化

• adj.

• ヨウ素の

関

I、I2、iodine、iodo