WordNet

unornamented; "a simple country schoolhouse"; "her black dress--simple to austerity"
any herbaceous plant having medicinal properties
(botany) of leaf shapes; of leaves having no divisions or subdivisions (同)unsubdivided
having few parts; not complex or complicated or involved; "a simple problem"; "simple mechanisms"; "a simple design"; "a simple substance"
an eye disease that damages the optic nerve and impairs vision (sometimes progressing to blindness); "contrary to popular belief, glaucoma is not always caused by elevated intraocular pressure"

PrepTutorEJDIC

『簡単な』容易な,分かりやすい / (複合に対して)単一の / 『単純な』,込み入っていない / 『純然たる』,全くの / 『飾り気のない』,簡素な,地味な,質素な / 『もったいぶらない』;誠実な,実直な / お人よしの,だまされやすい / 《文》地位のない,普通の,平(ひら)の
薬草,薬用植物
あおそこひ,緑内障(視力が減退する眼病)

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1. 幼児および小児における緑内障の概要 overview of glaucoma in infants and children
2. 閉塞隅角緑内障 angle closure glaucoma
3. 原発性乳児緑内障 primary infantile glaucoma
4. 開放隅角緑内障：治療 open angle glaucoma treatment
5. 開放隅角緑内障：疫学、臨床症状、および診断 open angle glaucoma epidemiology clinical presentation and diagnosis

Stothert AR1, Fontaine SN1, Sabbagh JJ1, Dickey CA2.
Experimental eye research.Exp Eye Res.2016 Mar;144:38-45. doi: 10.1016/j.exer.2015.08.017. Epub 2015 Aug 22.
A major drainage network involved in aqueous humor dynamics is the conventional outflow pathway, which is gated by the trabecular meshwork (TM). The TM acts as a molecular sieve, providing resistance to aqueous outflow, which is responsible for regulating intraocular pressure (IOP). If the TM is dam
PMID 26302411

Sirohi K1, Swarup G2.
Experimental eye research.Exp Eye Res.2016 Mar;144:54-63. doi: 10.1016/j.exer.2015.08.020. Epub 2015 Aug 21.
Certain mutations in optineurin (gene OPTN) are associated with primary open angle glaucoma. Optineurin is ubiquitously expressed but it shows high level of expression in certain cells and tissues including retinal ganglion cells. It interacts with many proteins, often acting as an adaptor to link t
PMID 26302410

Kumar S1, Malik MA1, Goswami S1, Sihota R2, Kaur J3.
Gene.Gene.2016 Feb 15;577(2):119-31. doi: 10.1016/j.gene.2015.11.032. Epub 2015 Nov 24.
PURPOSE: Glaucoma is a common disease often identified by high intraocular pressure, characteristic optic neuropathy and vision loss. It is currently a leading cause of blindness worldwide with no known cure. Primary open angle glaucoma (POAG) is the most common type of glaucoma worldwide. It is a m
PMID 26621382

The Mechanisms by Which Latanoprost Free Acid Inhibits Human Carbonic Anhydrase I and II(Biochemistry)

Sugimoto Ayako,Ikeda Hiroaki,Tsukamoto Hidetoshi [他],KIHIRA Kenji,TAKEDA Chiho,HIROSE Junzo,HATA Toshiyuki,BABA Eiko,ONO Yukio
Biological & pharmaceutical bulletin 31(5), 796-801, 2008-05-01
… Latanoprost, a prostaglandin F2alpha analogue, has been shown to be an effective ocular hypotensive agent when used alone on ocular hypertensive or open angle glaucoma patients. … The noncompetitive inhibition mechanism and the binding mode of latanoprost free acid indicate that the behavior of latanoprost free acid is very similar to that of simple anions. …
NAID 110006663930

2P1-C02 Quasi-static analysis of eye pressure measurement in non-contact tonometry

KEMPF Roland,KURITA Yuichi,IIDA Yoshichika,KANEKO Makoto,MISHIMA Hiromu K,TSUKAMOTO Hidetoshi,SUGIMOTO Eiichiro
ロボティクス・メカトロニクス講演会講演概要集 2006, "2P1-C02(1)"-"2P1-C02(3)", 2006
… The measurement of the internal eye pressure, or IntraOcular Pressure (IOP), is essential for the early detection and treatment of glaucoma. … It shows that a simple eye model can be used to capture the essence of the eye deformation. …
NAID 110008694161

神田貴之,木村泰朗,海老原伸行,中村眞二,渡部保男
順天堂医学 48(1), 39-48, 2002-07-10
目的:白色家兎を用いて簡便かつ再現性および安定性の高い実験緑内障モデルを作製する.方法:30ゲージ針を用いて白色家兎の前房水を0.2ml穿刺した後,3%アテロコラーゲン(0.1ml・0.2ml・0.25mlおよび0.3ml)を前房内に注入した.注入1,2,7,14,28および56日後に,トノペンXL眼圧計による眼圧測定および前眼部観察を行った.以上の処置は白色家兎の片眼だけに行い,他眼は対照とした …
NAID 10013253558