WordNet

an impairment of health or a condition of abnormal functioning
caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes" (同)morbid, pathologic, pathological

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1. アミロイドーシスの概要 overview of amyloidosis
2. アミロイド心筋症の臨床症状および診断 clinical manifestations and diagnosis of amyloid cardiomyopathy
3. 舞踏病の概要 overview of chorea
4. 認知機能低下および認知症の危険因子 risk factors for cognitive decline and dementia
5. アミロイド心筋症の治療 treatment of amyloid cardiomyopathy

Wang C1,2,3, Wang Z2, Zhou J2, Liu S2, Wu C2, Huang C2, Ding Y1,2.
International journal of cancer.Int J Cancer.2017 Mar 15;140(6):1457-1464. doi: 10.1002/ijc.30542. Epub 2016 Dec 27.
Ultraconserved regions (UCRs) are non-protein coding gene sequences that are strictly conserved across among different species. Emerging evidence demonstrates that transcribed ultraconserved regions (TUCRs) encoding noncoding RNAs serve as regulators of gene expression. In recent decades, increasing
PMID 27914101

Reversal of Beta-Amyloid-Induced Neurotoxicity in PC12 Cells by Curcumin, the Important Role of ROS-Mediated Signaling and ERK Pathway.

Fan CD1, Li Y1, Fu XT1, Wu QJ1, Hou YJ1, Yang MF1, Sun JY2, Fu XY3, Zheng ZC4, Sun BL5.
Cellular and molecular neurobiology.Cell Mol Neurobiol.2017 Mar;37(2):211-222. doi: 10.1007/s10571-016-0362-3. Epub 2016 Mar 14.
Progressive accumulation of beta-amyloid (Aβ) will form the senile plaques and cause oxidative damage and neuronal cell death, which was accepted as the major pathological mechanism to the Alzheimer's disease (AD). Hence, inhibition of Aβ-induced oxidative damage and neuronal cell apoptosis by age
PMID 26971524

Mechanisms of Alzheimer's Disease Pathogenesis and Prevention: The Brain, Neural Pathology, N-methyl-D-aspartate Receptors, Tau Protein and Other Risk Factors.

Kocahan S1,2, Doğan Z3.
Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology.Clin Psychopharmacol Neurosci.2017 Feb 28;15(1):1-8. doi: 10.9758/cpn.2017.15.1.1.
The characteristic features of Alzheimer's disease (AD) are the appearance of extracellular amyloid-beta (Aβ) plaques and neurofibrillary tangles in the intracellular environment, neuronal death and the loss of synapses, all of which contribute to cognitive decline in a progressive manner. A number
PMID 28138104

Cardiac amyloidosis in a heart transplant patient - A case report and retrospective analysis of amyloidosis evolution

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Intractable & Rare Diseases Research advpub(0), 2015
… We report a 72-year-old male patient with the diagnosis of senile systemic amyloidosis (SSA) in a transplanted heart 15 years after transplantation by the initial diagnosis of the dilated cardiomyopathy. … Additionally performed immunohistochemical analysis with anti-transthyretin antibody of the cardiac biopsies of the last 15 years enabled the possibility to show the evolution of this disease with characteristic biphasic pattern. …
NAID 130005008110

Cardiac amyloidosis in a heart transplant patient - A case report and retrospective analysis of amyloidosis evolution

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Intractable & Rare Diseases Research 4(1), 60-64, 2015
… We report a 72-year-old male patient with the diagnosis of senile systemic amyloidosis (SSA) in a transplanted heart 15 years after transplantation by the initial diagnosis of the dilated cardiomyopathy. … Additionally performed immunohistochemical analysis with anti-transthyretin antibody of the cardiac biopsies of the last 15 years enabled the possibility to show the evolution of this disease with characteristic biphasic pattern. …
NAID 130005008105

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The Tohoku Journal of Experimental Medicine 235(1), 29-37, 2015
… Osteoporosis is a common skeletal disease of the elderly, characterized by low bone mass and microstructural deterioration of bone tissue. … It is important to take appropriate measures to treat tooth loss in older people for preventing and/or treating senile osteoporosis. …
NAID 130004822425