網膜異形成、網膜異形成症、網膜形成不全
WordNet
- in or relating to the retina of the eye; "retinal cells"
- the innermost light-sensitive membrane covering the back wall of the eyeball; it is continuous with the optic nerve
- abnormal development (of organs or cells) or an abnormal structure resulting from such growth
PrepTutorEJDIC
- (目の)網膜
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/11/13 15:00:44」(JST)
[Wiki en表示]
Retinal dysplasia is an eye disease affecting the retina of animals and, less commonly, humans. It is usually a nonprogressive disease and can be caused by viral infections, drugs, vitamin A deficiency, or genetic defects. Retinal dysplasia is characterized by folds or rosettes (round clumps) of the retinal tissue.
Contents
- 1 Retinal dysplasia in dogs
- 1.1 Commonly affected breeds
- 2 Retinal dysplasia in other animals
- 3 See also
- 4 References
Retinal dysplasia in dogs
Most cases of retinal dysplasia in dogs are hereditary. It can involve one or both retinas. Retinal dysplasia can be focal, multifocal, geographic, or accompanied by retinal detachment. Focal and multifocal retinal dysplasia appears as streaks and dots in the central retina. Geographic retinal dysplasia appears as an irregular or horseshoe-shaped area of mixed hyper or hyporeflectivity in the central retina. Retinal detachment occurs with complete retinal dysplasia, and is accompanied by blindness in that eye. Cataracts or glaucoma can also occur secondary to retinal dysplasia. Other causes of retinal dysplasia in dogs include infection with canine adenovirus or canine herpesvirus, or radiation of the eye in newborns.
Commonly affected breeds
- Bedlington Terrier - complete retinal dysplasia.
- Sealyham Terrier - complete retinal dysplasia.
- Rottweiler - focal or multifocal.
- English Springer Spaniel - focal, multifocal, or geographic.
- American Cocker Spaniel - focal or multifocal.
- Beagle - focal or multifocal.
- Cavalier King Charles Spaniel - retinal folds, geographic, or retinal detachment.
- Labrador Retriever - focal, multifocal, geographic, or complete retinal dysplasia. It can also be seen in combination with a congenital skeletal disorder.
- Australian Shepherd - retinal dysplasia occurs with other eye disorders, such as an oval pupil, microcornea (small cornea), cataracts, and retinal detachment.[1]
Retinal dysplasia in other animals
- Cats - Retinal dysplasia occurs in utero or in newborns infected with feline leukemia virus or feline panleukopenia, which cause necrosis and disorganization of the retina. It appears as folds and rosettes.
- Cattle - Retinal dysplasia occurs in utero through infection with bovine viral diarrhea. It is also inherited in Shorthorns and Herefords. Both forms often cause retinal detachment.
- Sheep - Retinal dysplasia occurs by in utero infection with bluetongue disease.
- Horses - Retinal dysplasia is bilateral, not inherited, and appears as multifocal or geographic disease. It is usually accompanied by other eye problems.
- Chickens[1]
See also
- Progressive retinal atrophy
References
- ^ a b Gelatt, Kirk N. (ed.) (1999). Veterinary Ophthalmology (3rd ed. ed.). Lippincott, Williams & Wilkins. ISBN 0-683-30076-8.
UpToDate Contents
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English Journal
- Photoreceptor proliferation and dysregulation of cell cycle genes in early onset inherited retinal degenerations.
- Gardiner KL1, Downs L1, Berta-Antalics AI1,2, Santana E1, Aguirre GD1, Genini S3.
- BMC genomics.BMC Genomics.2016 Mar 11;17(1):221. doi: 10.1186/s12864-016-2477-9.
- BACKGROUND: Mitotic terminally differentiated photoreceptors (PRs) are observed in early retinal degeneration (erd), an inherited canine retinal disease driven by mutations in the NDR kinase STK38L (NDR2).RESULTS: We demonstrate that a similar proliferative response, but of lower magnitude, occurs i
- PMID 26969498
- Strabismus at Age 2 Years in Children Born Before 28 Weeks' Gestation: Antecedents and Correlates.
- VanderVeen DK1, Allred EN2, Wallace DK3, Leviton A4; ELGAN Study Investigators.
- Journal of child neurology.J Child Neurol.2016 Mar;31(4):451-60. doi: 10.1177/0883073815599258. Epub 2015 Sep 8.
- Children born very preterm are at greater risk of ophthalmic morbidities, including strabismus, than children born at term. We evaluated perinatal factors associated with strabismus at age 2 years in a large population of infants delivered before 28 weeks' gestation. A total of 996 infants in the mu
- PMID 26350726
- AAV-mediated Gene Therapy Halts Retinal Degeneration in PDE6β-deficient Dogs.
- Pichard V1, Provost N1, Mendes-Madeira A1, Libeau L1, Hulin P2, Tshilenge KT1, Biget M1, Ameline B1, Deschamps JY3, Weber M4, Le Meur G4, Colle MA5, Moullier P1,6, Rolling F1.
- Molecular therapy : the journal of the American Society of Gene Therapy.Mol Ther.2016 Feb 9. doi: 10.1038/mt.2016.37. [Epub ahead of print]
- We previously reported that subretinal injection of AAV2/5 RK.cpde6β allowed long-term preservation of photoreceptor function and vision in the rod-cone dysplasia type 1 (rcd1) dog, a large animal model of naturally occurring PDE6β deficiency. The present study builds on these earlier findings to
- PMID 26857842
Japanese Journal
- Persistent hyperplastic primary vitreous in two piglets
- MURAKAMI Tomoaki,MIYOSHI Tomoyuki,TAKAHASHI Natsumi,KANGAWA Akihisa
- The Journal of Veterinary Medical Science 81(3), 357-360, 2019
- <p>Two Large Yorkshire piglets were diagnosed as persistent hyperplastic primary vitreous (PHPV). In case 1, the white cord-like structure extending from optic disc to lens was observed in the n …
- NAID 130007613177
- マスト細胞の活性化に基づく未熟児網膜症の病態発症メカニズム
- 松田 研史郎,田中 あかね,松田 浩珍
- Functional Food Research 14(0), 4-9, 2018
- 近年,新生児・周産期医療の発展や妊婦の骨格構造の変化,多胎率,高齢出生の増加などによって在胎週数が短く出生体重1,000 g未満で産まれる超低出生体重児が増加している.超低出生体重児は組織未成熟による機能不全のため,肺異形成症候群や動脈管開存症,貧血など種々の合併症を引き起こすリスクがある.そのため出生後直ちに高酸素環境での保育が必要で,分娩時からの集中治療において大きな酸素濃度の変 …
- NAID 130007612139
- 黄斑低形成と黄斑部網膜皺襞を伴ったsepto-optic dysplasiaの一例
- 徳久 照朗,稲葉 万弓,曽根田 瞬,仁科 幸子,敷島 敬悟
- 神経眼科 33(4), 379-384, 2016
- … 稀な黄斑低形成および黄斑部網膜皺襞を伴う中隔視神経異常症(septo-optic dysplasia(SOD))の症例を経験したので報告する.<br>症例は9才の女児.新生児期に低血糖発作を繰り返し,2歳時に成長ホルモン分泌不全と診断された.同時に内斜視と両側視神経萎縮を指摘され,精査のため当科を紹介受診した.初診時,右眼光覚弁(+),左眼視力(0.9).眼底検査で両側視神経低形成,網膜血管の蛇行および光干渉断層 …
- NAID 130005295932
Related Links
- dysplasia [dis-pla´zhah] an abnormality of development; in pathology, alteration in size, shape, and organization of adult cells. See also dysgenesis. adj., adj dysplas´tic. bronchopulmonary dysplasia chronic lung disease of premature ...
- There is no treatment for retinal dysplasia. With their acute senses of smell and hearing, dogs can compensate very well for visual difficulties, particularly in familiar surroundings. In fact owners may be unaware of the extent of vision ...
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