残尿、残尿感

WordNet

relating to or indicating a remainder; "residual quantity" (同)residuary
(often plural) a payment that is made to a performer or writer or director of a television show or commercial that is paid for every repeat showing; "he could retire on his residuals"
liquid excretory product; "there was blood in his urine"; "the child had to make water" (同)piss, pee, piddle, weewee, water

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残りの,残留の / 残余
尿,小便

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/08/21 04:22:12」(JST)

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Urinary retention, also known as ischuria, is a lack of ability to urinate. It is a common complication of benign prostatic hyperplasia (BPH), although it can also be caused by nerve dysfunction, constipation, infection, or medications (including anticholinergics, antidepressants, COX-2 inhibitors,^[1] amphetamines and opiates). Diagnosis and/or treatment may require use of a catheter or prostatic stent.

Signs and symptoms

Urinary retention is characterised by poor urinary stream with intermittent flow, straining, a sense of incomplete voiding and hesitancy (a delay between trying to urinate and the flow actually beginning). As the bladder remains full, it may lead to incontinence, nocturia (need to urinate at night) and high frequency. Acute retention causing complete anuria is a medical emergency, as the bladder may distend (stretch) to enormous sizes and possibly tear if not dealt with quickly. If the bladder distends enough it will begin to become painful. The increase in pressure in the bladder can also prevent urine from entering the ureters or even cause urine to pass back up the ureters and get into the kidneys, causing hydronephrosis, and possibly pyonephrosis, kidney failure and sepsis. A person should go straight to an emergency department as soon as possible if unable to urinate when having a painfully full bladder.

Causes

In the bladder

Detrusor sphincter dyssynergia
Neurogenic bladder (commonly pelvic splanchic nerve damage, cauda equina syndrome, descending cortical fibers lesion, pontine micturation or storage center lesions, demyelinating diseases or Parkinson's disease)
Iatrogenic (doctor-caused) scarring of the bladder neck (commonly from removal of indwelling catheters or cystoscopy operations)
Damage to the bladder

In the prostate

Benign prostatic hyperplasia
Prostate cancer and other pelvic malignancies
Prostatitis

Penile urethra

Congenital urethral valves
Phimosis or pinhole meatus
Circumcision
Obstruction in the urethra, for example a metastasis or a precipitated pseudogout crystal in the urine
STD lesions (gonorrhoea causes numerous strictures, leading to a "rosary bead" appearance, whereas chlamydia usually causes a single stricture)

Other

Paruresis ("shy bladder syndrome")- in extreme cases, urinary retention can result
Consumption of some psychoactive substances, mainly stimulants, such as MDMA and amphetamine.
Use of NSAIDs or drugs with anticholinergic properties.
Stones or metastases can theoretically appear anywhere along the urinary tract, but vary in frequency depending on anatomy
Muscarinic antagonist such as Atropine and Scopolamine

Paruresis, inability to urinate in the presence of others (such as in a public restroom), may also be classified as a type of urinary retention, although it is psychological rather than biological.

Diagnosis

As seen on axial CT

Urine flow tests may aid in establishing the type of micturition (urination) abnormality. Common findings, determined by ultrasound of the bladder, include a slow rate of flow, intermittent flow, and a large amount of urine retained in the bladder after urination. A normal test result should be 20-25 mL/sec peak flow rate. A post-void residual urine greater than 50 ml is a significant amount of urine and increases the potential for recurring urinary tract infections. In adults older than 60 years, 50-100 ml of residual urine may remain after each voiding because of the decreased contractility of the detrusor muscle. In chronic retention, ultrasound of the bladder may show massive increase in bladder capacity (normal capacity being 400-600 ml).

Determination of the serum prostate-specific antigen (PSA) may aid in diagnosing or ruling out prostate cancer, though this is also raised in BPH and prostatitis. A TRUS biopsy of the prostate (trans-rectal ultra-sound guided) can distinguish between these prostate conditions. Serum urea and creatinine determinations may be necessary to rule out backflow kidney damage. Cystoscopy may be needed to explore the urinary passage and rule out blockages.

In acute cases of urinary retention where associated symptoms in the lumbar spine are present such as pain, numbness (saddle anesthesia), parasthesias, decreased anal sphincter tone, or altered deep tendon reflexes, an MRI of the lumbar spine should be considered to further assess Cauda Equina Syndrome.

Complications

Urinary retention often occurs without warning. It is basically the inability to pass urine. In some people, the disorder starts gradually but in others it may appear suddenly. Acute urinary retention is a medical emergency and requires prompt treatment. The pain can be excruciating when urine is not able to flow out. Moreover one can develop severe sweating, chest pain, anxiety and high blood pressure. Other patients may develop a shock like condition and may be require an admission to the hospital. It is not unusual for an individual to develop a heart attack after suffering acute urinary retention. Other more serious complications of untreated urinary retention include bladder damage and chronic kidney failure.^[2] Urinary retention is a disorder which is treated in a hospital and the quicker one seeks treatment, the fewer the complications.

In the longer term, obstruction of the urinary tract may cause:

Bladder stones
Atrophy of the detrusor muscle (atonic bladder is an extreme form)
Hydronephrosis (congestion of the kidneys)
Hypertrophy of the detrusor muscle (the muscle which squeezes the bladder to empty it during urination)
Diverticula (the formation of pouches) in the bladder wall (which can lead to stones and infection)

Treatment

In acute urinary retention, urinary catheterization, placement of a prostatic stent or suprapubic cystostomy relieves the retention. In the longer term, treatment depends on the cause. BPH may respond to alpha blocker and 5-alpha-reductase inhibitor therapy, or surgically with prostatectomy or transurethral resection of the prostate (TURP). Older patients with ongoing problems may require continued intermittent self catheterization.^[3] 5-alpha-reductase inhibitor increase the chance of normal urination following catheter removal.^[4]

Complications

The acute urinary retention is treated by placement of a urinary catheter (small thin flexible tube) into the bladder. This can be either an intermittent catheter or a Foley catheter that is emplaced with a small inflatable bulb that holds the catheter in place.

Intermittent catheterization can be done by a health care professional (nurse/ doctor) or by the patient himself /herself (clean intermittent self catheterization). Intermittent catheterization performed at the hospital will be a sterile technique done by nurses /doctores, while patients can be taught to use a self catheterization^[5] technique in one simple demonstration, and that reduces the rate of infection from longer term Foley catheters. Self catheterization requires doing the procedure every 3 or 4 hours 4-6 times a day. The chronic form of urinary retention may require some type of surgical procedure. While both procedures are relatively safe, complications can occur.

In acute urinary retention, the treatment requires urgent placement of a urinary catheter (tube) into the urethra and into the bladder. These catheters are usually inserted by health care professionals. However, if the procedure is not accomplished in a sterile fashion, it can introduce bacteria into the bladder. This can result in an infection of the entire urinary tract. Therefore, sterile technique is a must when inserting a foley catheter. Careful washing of hands, meatus, and reusable catheters are also necessary with clean self catheterization techniques.^[6]

Sometimes the permanent urinary catheter may cause discomfort and pain which often lasts for several days. The urinary catheter must be placed into the bladder and not near the prostate gland. Placement of the catheter near the prostate can lead to bleeding and significant irritation. In most patients with benign prostate hyperplasia (BPH), a procedure known as transurethral resection of the prostate (TURP) is performed to relieve bladder obstruction. The surgery is done with a small lighted instrument which is inserted into the urethra under anesthesia. The surgeon can core out the enlarged prostate and relieve obstruction. However, the procedure does have risks. There are risks of anesthesia which may include allergy to medications or low blood pressure which results from spinal anesthesia.^[7]

The surgical complications from TURP include a bladder infection, bleeding from the prostate, scar formation, inability to hold urine and inability to have an erection. The majority of these complications are short lived and most individuals recover fully within 6–12 months.^[8] Some people with BPH are treated with medications like finasteride or dutasteride to decrease prostate enlargement. The drugs only work for mild cases of BPH but also have mild side effects. Some of the medications decrease libido and may cause dizziness, fatigue and lightheadedness. Unfortunately, medications only work in less than 5 percent of individuals with BPH.^[9]

Epidemiology

Urinary retention is a common disorder in elderly males. The most common cause of urinary retention is BPH. This disorder starts around age 50 and symptoms may appear after 10–15 years. BPH is a progressive disorder and narrows the neck of the bladder leading to urinary retention. By the age of 70, almost 10 percent of males have some degree of BPH and 33% have it by the eighth decade of life. While BPH rarely causes sudden urinary retention, the condition can become acute in the presence of certain medications (blood pressure pills, anti histamines, antiparkinson medications), after spinal anaesthesia or stroke.

In young males, the most common cause of urinary retention is infection of the prostate (known as "acute prostatitis"). The infection is acquired during sexual intercourse and presents with low back pain, penile discharge, low grade fever and an inability to pass urine. The exact numbers of individuals with acute prostatitis is unknown because many do not always seek treatment. In the USA, at least 1-3 percent of males under the age of 40 develop urinary difficulty as a result of acute prostatitis. Most physicians and other health care professionals are aware of these disorders. Worldwide, both BPH and acute prostatitis have been found to occur in males of all races, color and ethnic backgrounds. Cancers of the urinary tract can cause urinary obstruction but the process is more gradual. Bladder cancer, prostate or ureters can gradually obstruct urine output. Cancers often present with blood in the urine, weight loss, lower back pain or gradual distension in the flanks.^[10]

References

^ http://www.healthywomen.org/resources/womenshealthinthenews/dbhealthnews/nsaidpainkillersmayraiseurinaryretentionrisk
^ General information on urinary retention 2010-02-10
^ http://www.nlm.nih.gov/medlineplus/ency/article/003972.htm
^ Zeif HJ, Subramonian K (2009). "Alpha blockers prior to removal of a catheter for acute urinary retention in adult men". Cochrane Database Syst Rev (4): CD006744. doi:10.1002/14651858.CD006744.pub2. PMID 19821385.
^ http://www.nlm.nih.gov/medlineplus/ency/article/003972.htm
^ University of Michigan Health System. "Transurethral Resection of the Prostate" 2010-02-10.
^ eMedicine Health. "Inability to urinate" 2010-02-10.
^ National kidney and urologic diseases information clearinghouse. "Urinary retention overview" 2010-02-10.
^ What is benign prostatic hyperplasia? Family Doctor online portal. Retrieved on 2010-02-10
^ Urologic Emergencies Urology Channel portal. 2010-02-10

UpToDate Contents

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1. 急性尿閉 acute urinary retention
2. 腎不全における尿量および残存腎機能 urine output and residual renal function in renal failure
3. 尿失禁の臨床症状および診断 clinical presentation and diagnosis of urinary incontinence
4. 前立腺肥大症の臨床症状および診断 clinical manifestations and diagnosis of benign prostatic hyperplasia
5. 尿失禁女性の尿流動態検査 urodynamic evaluation of women with incontinence

English Journal

Perioperative urinary retention, short-term functional outcome and mortality rates of elderly hip fracture patients.

Adunsky A, Nenaydenko O, Koren-Morag N, Puritz L, Fleissig Y, Arad M.Author information Department of Geriatric Medicine and Rehabilitation, Sheba Medical Center, Tel Hashomer, Ramat-Gan, Israel; The Orthogeriatric Hip Fracture Unit, Sheba Medical Center, Tel Hashomer, Ramat-Gan, Israel; Sackler School of Medicine, Tel-Aviv University, Ramat Aviv, Israel.AbstractAIM: Perioperative urinary retention (POUR) is common among hip fracture patients. The aim of the present study was to compare the prevalence, risk factors, functional outcomes and survival rates of patients with and without POUR.
Geriatrics & gerontology international.Geriatr Gerontol Int.2014 Jan 12. doi: 10.1111/ggi.12229. [Epub ahead of print]
AIM: Perioperative urinary retention (POUR) is common among hip fracture patients. The aim of the present study was to compare the prevalence, risk factors, functional outcomes and survival rates of patients with and without POUR.METHODS: This was a retrospective chart review study that was carried
PMID 24418251

Novel constant-pressure irrigation technique for the treatment of renal pelvic tumors after ipsilateral ureterectomy.

Nakamura K, Terada N, Sugino Y, Yamasaki T, Matsui Y, Imamura M, Okubo K, Kamba T, Yoshimura K, Ogawa O.Author information Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.AbstractWe herein report a case of a renal pelvic tumor that developed in the residual left renal pelvis after right nephroureterectomy, left ureterectomy and total cystectomy in a patient with multiple urothelial tumors. The tumor was endoscopically ablated through a nephrostomy tract, and mitomycin C irrigation was carried out. We designed a novel constant-pressure irrigation system for effective and safe irrigation into the closed space of the renal pelvis. We created a hole in the urine bag tube, inserted a 5-Fr open-end ureteral catheter through the hole and kept the tip of the catheter at the end of the nephrostomy tube. The urine bag tube was placed 20 cm above the kidney level, and mitomycin C was continuously irrigated into the renal pelvis for 1 h. Six-weekly treatments were carried out, and tumor recurrence was not identified for 1 year.
International journal of urology : official journal of the Japanese Urological Association.Int J Urol.2014 Jan 9. doi: 10.1111/iju.12386. [Epub ahead of print]
We herein report a case of a renal pelvic tumor that developed in the residual left renal pelvis after right nephroureterectomy, left ureterectomy and total cystectomy in a patient with multiple urothelial tumors. The tumor was endoscopically ablated through a nephrostomy tract, and mitomycin C irri
PMID 24405373

Extraperitoneal Laparoscopic Adenomectomy (Madigan) Versus Bipolar Transurethral Resection of the Prostate for Benign Prostatic Hyperplasia Greater Than 80 mL: Complications and Functional Outcomes After 3-Year Follow-Up.

Xie JB, Tan YA, Wang FL, Xuan Q, Sun YW, Xiao J, Zhu YP, Zhou LY.Author information Department of Urology, Anhui Provincial Hospital Affiliated to Anhui Medical University , Hefei, China .AbstractAbstract Purpose: To compare the performance of voluminous benign prostatic hyperplasia patients who have received laparoscopic simple prostatectomy (LSP) with the patients who have received bipolar transurethral resection of the prostate (B-TURP) in their perioperative and 3-year follow-up period. Methods: Ninety patients with prostate volumes >80 mL (range 80-130 mL) were randomly assigned to either LSP or B-TURP surgery type. The patients were followed up at 1, 3, 6, 12, 24, and 36 months postoperatively. Perioperative and follow-up characteristics were then recorded and compared. Results: More blood loss, greater resected adenoma volume, and shorter catheterization duration were recorded in LSP group than that of B-TURP group (140.1±81.5 vs 93.1±54.0 mL; 65.3±13.8 vs 49.0±12.7 mL; 3.3±1.2 vs 3.8±1.0 days; p<0.05). None of the patients in LSP group reported complications out of 30 days, while 1 case of urethral stricture, 36 cases of retrograde ejaculation, 1 case of bladder neck contracture, and 2 cases of recurrence were recorded in B-TURP group. At 1, 3, 6, and 12 months postoperatively, there were no significant differences in terms of postvoid residual urine volume, maximal urinary flow rate (Qmax), and International Prostate Symptom Score between the two groups (p>0.05). In contrast, the differences became significant at 24 and 36 months (p<0.05). Conclusions: Compared with B-TURP, LSP with Madigan technique is accompanied by less residual adenoma, shorter catheterization time, and more blood loss. Further, the risk of late complications is lower with LSP and, in terms of functional outcomes, LSP appears to be better than B-TURP beyond 2 years.
Journal of endourology / Endourological Society.J Endourol.2014 Jan 7. [Epub ahead of print]
Abstract Purpose: To compare the performance of voluminous benign prostatic hyperplasia patients who have received laparoscopic simple prostatectomy (LSP) with the patients who have received bipolar transurethral resection of the prostate (B-TURP) in their perioperative and 3-year follow-up period.
PMID 24229434

Japanese Journal

排尿障害を受診動機とする包茎を合併した高齢者乾燥性閉塞性亀頭炎の治療経験

根本勺,石舘卓三
泌尿器科紀要 = Acta urologica Japonica 59(6), 341-346, 2013-06
… Preoperative average international prostate symptom score, average maximum urinary flow rate, and average volume of residual urine were 20.7±6.3 points (n＝8), 5.1±3.6 ml/s (n＝5), and 85.4±77.3 ml (n＝8), respectively. … Some of the patient's complaints, such as severe dribbling of urine, urinary stream division, and ballooning of the foreskin, were not included in the items of the major questionnaire on urination. …
NAID 120005298151

Intraprostatic Botulinum Neurotoxin Type A Injection for Benign Prostatic Hyperplasia:Preliminary Results with a Newly Purified Neurotoxin

Yokoyama Teruhiko,Yamamoto Yumiko,Suzuki Tomonori,Oguma Keiji,Nagai Atsushi
Acta Medica Okayama 66(4), 291-297, 2012-08
… Evaluation included uroflowmetry, postvoid residual urine volume (PVR), PV, and International Prostate Symptom Score (IPSS) measured at baseline and 1, 3, 6, and 12 months post-treatment. …
NAID 120004622477