WordNet

secure against; "immune from taxation as long as he resided in Bermuda"; "immune from criminal prosecution"
a person who is immune to a particular infection
relating to or conferring immunity (to disease or infection) (同)resistant
(usually followed by `to'
relating to the condition of immunity; "the immune system"
an acute viral disease of the nervous system of warm-blooded animals (usually transmitted by the bite of a rabid animal); rabies is fatal if the virus reaches the brain (同)hydrophobia, lyssa, madness
a family of proteins found in blood and milk and muscle and in plant seed

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1. 狂犬病免疫グロブリンとワクチン rabies immune globulin and vaccine
2. 狂犬病の治療 treatment of rabies
3. 狂犬病の臨床的特徴および診断 clinical manifestations and diagnosis of rabies
4. 中央アフリカへの旅行によって感染する可能性のある疾患 diseases potentially acquired by travel to central africa
5. 狂犬病予防の実施時期 when to use rabies prophylaxis

Development of broad-spectrum human monoclonal antibodies for rabies post-exposure prophylaxis.

De Benedictis P1, Minola A2, Rota Nodari E1, Aiello R1, Zecchin B1, Salomoni A1, Foglierini M3, Agatic G2, Vanzetta F2, Lavenir R4, Lepelletier A4, Bentley E5, Weiss R6, Cattoli G1, Capua I1, Sallusto F3, Wright E5, Lanzavecchia A7, Bourhy H4, Corti D8.
EMBO molecular medicine.EMBO Mol Med.2016 Mar 18. pii: e201505986. doi: 10.15252/emmm.201505986. [Epub ahead of print]
Currently available rabies post-exposure prophylaxis (PEP) for use in humans includes equine or human rabies immunoglobulins (RIG). The replacement of RIG with an equally or more potent and safer product is strongly encouraged due to the high costs and limited availability of existing RIG. In this s
PMID 26992832

Benefits of using heterologous polyclonal antibodies and potential applications to new and undertreated infectious pathogens.

Dixit R1, Herz J2, Dalton R3, Booy R4.
Vaccine.Vaccine.2016 Feb 24;34(9):1152-61. doi: 10.1016/j.vaccine.2016.01.016. Epub 2016 Jan 20.
BACKGROUND: Passive immunotherapy using polyclonal antibodies (immunoglobulins) has been used for over a century in the treatment and post-exposure prophylaxis of various infections and toxins. Heterologous polyclonal antibodies are obtained from animals hyperimmunised with a pathogen or toxin.AIMS:
PMID 26802604

A novel variable antibody fragment dimerized by leucine zippers with enhanced neutralizing potency against rabies virus G protein compared to its corresponding single-chain variable antibody fragment.

Li Z1, Cheng Y1, Xi H1, Gu T2, Yuan R1, Chen X1, Jiang C2, Kong W3, Wu Y4.
Molecular immunology.Mol Immunol.2015 Dec;68(2 Pt A):168-75. doi: 10.1016/j.molimm.2015.06.027. Epub 2015 Aug 29.
Fatal rabies can be prevented effectively by post-exposure prophylactic (PEP) with rabies immunoglobulin (RIG). Single-chain variable fragments (scFv), which are composed of a variable heavy chain (VH) and a variable light chain (VL) connected by a peptide linker, can potentially be used to replace
PMID 26325475

The development of monoclonal human rabies virus-neutralizing antibodies as a substitute for pooled human immune globulin in the prophylactic treatment of rabies virus exposure

高山直秀
感染症学雑誌 : 日本伝染病学会機関誌 : the journal of the Japanese Association for Infectious Diseases 69(1), 73-78, 1995-01-20
日本では昭和32年以降狂犬病の国内発生は1件もなく, 輸入例も昭和45年の1例のみであるが, 海外ではなお多くの地域で狂犬病の発生をみている. 海外で狂犬病危険動物に咬まれ, 曝露後免疫のため当院を受診した29名について検討した. 受傷地はタイ, 受傷部位は下肢, 加害動物はイヌが最も多かった. 受傷地で発病予防を受けた被害者群と受けなかった被害者群はほぼ同数であったが, アジア・アフリカ地域で被 …
NAID 10008725255