FasL-triggered death of Jurkat cells requires caspase 8-induced, ATP-dependent cross-talk between Fas and the purinergic receptor P2X(7).
Aguirre A, Shoji KF, Sáez JC, Henríquez M, Quest AF.SourceFacultad de Medicina, Centro de Estudios Moleculares de la Célula, Universidad de Chile, Santiago, Chile.
Journal of cellular physiology.J Cell Physiol.2013 Feb;228(2):485-93. doi: 10.1002/jcp.24159.
Fas ligation via the ligand FasL activates the caspase-8/caspase-3-dependent extrinsic death pathway. In so-called type II cells, an additional mechanism involving tBid-mediated caspase-9 activation is required to efficiently trigger cell death. Other pathways linking FasL-Fas interaction to activat
Braganhol E, Wink MR, Lenz G, Battastini AM.SourceCentro de Ciências Químicas, Farmacêuticas e de Alimentos (CCQFA), Universidade Federal de Pelotas (UFPel), Campus Capão do Leão S/N, 354, Pelotas, CEP 96010900, RS, Brazil. elizandra.braganhol@ufrgs.br
Advances in experimental medicine and biology.Adv Exp Med Biol.2013;986:81-102. doi: 10.1007/978-94-007-4719-7_5.
Among the pathological alterations that give tumor cells invasive potential, purinergic signaling is emerging as an important component. Studies performed in in vitro, in vivo and ex vivo glioma models indicate that alterations in the purinergic signaling are involved in the progression of these tum
Journal of Pharmacological Sciences 120(4), 288-295, 2012
ATP and hydrolysis products of ATP like adenosine regulate the chemotaxis of neutrophils by activating purinoceptors and adenosine receptors. The present study was designed to examine exogenous ATP, a …
Definition from Wiktionary, the free dictionary Jump to: navigation, search English [edit] Etymology [edit] Blend of purinergic and receptor Noun [edit] Wikipedia has an article on: Purinergic receptor Wikipedia purinoceptor (plural ...
A purinoceptor is a cell surface receptor for the purinergic nucleotides ATP and ADP and for the purine nucleotide, adenosine. Purinergic System ... Editors Prof. Stefan Offermanns Prof. Walter Rosenthal Free Articles ...