prostaglandin H2 receptor

• プロスタグランジンH2受容体、プロスタグランジンH2レセプター

関

prostaglandin H2-thromboxane A2 receptor、thromboxane A2 receptor

WordNet

1. the 8th letter of the Roman alphabet (同)h
2. a potent substance that acts like a hormone and is found in many bodily tissues (and especially in semen); produced in response to trauma and may affect blood pressure and metabolism and smooth muscle activity
3. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

PrepTutorEJDIC

1. hydrogenの化学記号
2. 鉛筆の硬度 / 《俗》heroin
3. =sense organ / 受信装置

UpToDate Contents

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• 1. 抗潰瘍薬：作用機序、薬理作用、副作用 antiulcer medications mechanism of action pharmacology and side effects
• 2. 非ステロイド性抗炎症剤（NSAIDs）（アスピリンを含む）：胃十二指腸障害の一次予防 nsaids including aspirin primary prevention of gastroduodenal toxicity
• 3. 非ステロイド性抗炎症剤（NSAIDs）（アスピリンを含む）：胃十二指腸障害の病因 nsaids including aspirin pathogenesis of gastroduodenal toxicity
• 4. 集中治療室（ICU）におけるストレス潰瘍の予防 stress ulcer prophylaxis in the intensive care unit
• 5. 胃酸分泌の生理学 physiology of gastric acid secretion

English Journal

• Mast Cell Activation Syndrome.

• Frieri M1.
• Clinical reviews in allergy & immunology.Clin Rev Allergy Immunol.2015 May 6. [Epub ahead of print]
• Mast cell activation syndrome (MCAS) involves the skin, gastrointestinal, cardiovascular, respiratory, and neurologic systems, classified as primary, secondary, and idiopathic. Earlier criteria for MCAS diagnosis included episodic symptoms with mast cell mediators affecting two or more organ systems
• PMID 25944644

• The novel prostaglandin I2 mimetic ONO-1301 escapes desensitization in an antiplatelet effect due to its inhibitory action on thromboxane A2 synthesis in mice.

• Kashiwagi H1, Yuhki K1, Kojima F1, Kumei S1, Takahata O1, Sakai Y1, Narumiya S1, Ushikubi F2.
• The Journal of pharmacology and experimental therapeutics.J Pharmacol Exp Ther.2015 May;353(2):269-78. doi: 10.1124/jpet.115.222612. Epub 2015 Mar 4.
• ONO-1301 [(E)-[5-[2-[1-phenyl-1-(3-pyridyl)methylidene-aminooxy]ethyl]-7,8-dihydronaphthalene-1-yloxy]acetic acid] is a novel prostaglandin (PG) I2 mimetic with inhibitory activity on the thromboxane (TX) A2 synthase. Interestingly, ONO-1301 retains its inhibitory effect on platelet aggregation afte
• PMID 25740898

• Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4+ T cell-dendritic cell interactions.

• Moalli F1, Cupovic J2, Thelen F1, Halbherr P1, Fukui Y3, Narumiya S4, Ludewig B2, Stein JV5.
• The Journal of experimental medicine.J Exp Med.2014 Dec 15;211(13):2507-17. doi: 10.1084/jem.20140137. Epub 2014 Dec 8.
• Interactions between dendritic cells (DCs) and T cells control the decision between activation and tolerance induction. Thromboxane A2 (TXA2) and its receptor TP have been suggested to regulate adaptive immune responses through control of T cell-DC interactions. Here, we show that this control is ac
• PMID 25488981

Japanese Journal

• NSAIDs潰瘍の予防・治療における抗潰瘍薬の位置づけ 抗潰瘍薬選択のポイントとその留意点 (特集 NSAIDs潰瘍--最新の予防・治療) -- (NSAIDs潰瘍の予防・治療戦略)

• 木下 芳一,玉川 祐司
• 日本臨床 69(6), 1044-1048, 2011-06
• NAID 40018850024

• R-(-)-.ALPHA.-Methylhistamine, a Histamine H3 Receptor Agonist, Induces Endothelium-Dependent Vasodilation in Rat Mesenteric Resistance Arteries

• Sun Pengyuan,Jin Xin,Koyama Toshihiro [他],Li Simin,Kitamura Yoshihisa,Kawasaki Hiromu
• Biological and Pharmaceutical Bulletin 33(1), 58-63, 2010
• … A novel histamine receptor subtype, histamine H3 receptor, mediates inhibition of peripheral autonomic neurotransmission. … The present study was designed to examine vascular effects of histamine H3 receptor by using a selective histamine H3 receptor agonist, R-(−)-α methylhistamine (α-methylhistamine), in rat mesenteric resistance arteries. …
• NAID 130000140192

• The CD70-CD27 interaction during the stimulation with dendritic cells promotes naive CD4+ T cells to develop into T cells producing a broad array of immunostimulatory cytokines in humans

• HASHIMOTO OKADA Mutsumi,KITAWAKI Toshio,KADOWAKI Norimitsu,IWATA Satoshi,MORIMOTO Chikao,HORI Toshiyuki,UCHIYAMA Takashi
• International immunology 21(8), 891-904, 2009-08-01
• … Here, we show that human myeloid dendritic cells (mDCs) and plasmacytoid dendritic cells stimulated with CD40 ligand together with pro-inflammatory cytokines or Toll-like receptor ligands express CD70. … Thymic stromal lymphopoietin plus prostaglandin E2 also induced CD70 on mDCs. …
• NAID 10025387511

Related Links

• Prostaglandin H2 induces the migration of human eosinophils ...

1. J Leukoc Biol. 2009 Jan;85(1):136-45. doi: 10.1189/jlb.0608387. Epub 2008 Oct 3. Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells ...

• Thromboxane A2/prostaglandin H2 receptor activation ...

1. Arterioscler Thromb Vasc Biol. 2006 Mar;26(3):488-93. Epub 2005 Dec 29. Thromboxane A2/prostaglandin H2 receptor activation mediates angiotensin II-induced postischemic neovascularization. Michel F(1), Silvestre ...

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★リンクテーブル★

リンク元	「prostaglandin H2-thromboxane A2 receptor」「プロスタグランジンH2レセプター」「thromboxane A2 receptor」「プロスタグランジンH2受容体」
関連記事	「H」「prostaglandin」「prostaglandin H2」「prostaglandins」

「prostaglandin H2-thromboxane A2 receptor」

　　[★]

• プロスタグランジンH2/トロンボキサンA2受容体、プロスタグランジンH2/トロンボキサンA2レセプター

関

prostaglandin H2 receptor、thromboxane A2 receptor

「プロスタグランジンH2レセプター」

　　[★]

英

prostaglandin H2 receptor

関

トロンボキサンA2受容体、プロスタグランジンH2/トロンボキサンA2受容体、プロスタグランジンH2受容体

「thromboxane A2 receptor」

　　[★]

• トロンボキサンA2受容体

関

prostaglandin H2 receptor、prostaglandin H2-thromboxane A2 receptor、TXA2 receptor

「プロスタグランジンH2受容体」

　　[★]

英

prostaglandin H2 receptor

関

プロスタグランジンH2レセプター

「H」

　　[★]

• 食道裂孔
• ヒスチジン
• 水素

　 　 　

「prostaglandin」

　　[★] プロスタグランジン prostaglandins PG

　

「prostaglandin H2」

　　[★]

プロスタグランジンH2

関

PGH2

「prostaglandins」

　　[★] プロスタグランジン