product inhibition

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WordNet

1. a chemical substance formed as a result of a chemical reaction; "a product of lime and nitric acid"
2. a consequence of someones efforts or of a particular set of circumstances; "skill is the product of hours of practice"; "his reaction was the product of hunger and fatigue"
3. an artifact that has been created by someone or some process; "they improve their product every year"; "they export most of their agricultural production" (同)production
4. a quantity obtained by multiplication; "the product of 2 and 3 is 6" (同)mathematical product
5. (physiology) the process whereby nerves can retard or prevent the functioning of an organ or part; "the inhibition of the heart by the vagus nerve"
6. (psychology) the conscious exclusion of unacceptable thoughts or desires (同)suppression
7. the quality of being inhibited

PrepTutorEJDIC

1. 『産物』;製品 / (…の)結果,帰結《+『of』+『名』(do『ing』)》 / (数の)積 / (化学の)生成物
2. 禁止; 抑制; （心理学で）抑制; （化学で）（反応の）阻害, 抑制

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/03/18 01:10:07」(JST)

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Product inhibition is a type of enzyme inhibition where the product of an enzyme reaction binds to the enzyme and inhibits its activity.

This can be important in the regulation of metabolism as a form of negative feedback controlling metabolic pathways. Product inhibition is also an important topic in biotechnology, as overcoming this effect can increase the yield of a product, such as an antibiotic.

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• 1. 高血圧のマネージメントにおけるバゾペプチターゼ阻害剤 vasopeptidase inhibition in the management of hypertension
• 2. C型肝炎ウイルス感染に対する試験的治療 investigational therapies for hepatitis c virus infection
• 3. 先天性および後天性鉄芽球性貧血の原因 causes of congenital and acquired sideroblastic anemias
• 4. 進行黒色腫に対する免疫チェックポイント分子阻害による免疫療法 immunotherapy of advanced melanoma with immune checkpoint inhibition
• 5. 肥満細胞：表面受容体とシグナル伝達 mast cells surface receptors and signal transduction

English Journal

• Apple phenolics as inhibitors of the carbonylation pathway during in vitro metal-catalyzed oxidation of myofibrillar proteins.

• Rysman T1, Utrera M2, Morcuende D3, Van Royen G4, Van Weyenberg S5, De Smet S6, Estévez M7.
• Food chemistry.Food Chem.2016 Nov 15;211:784-90. doi: 10.1016/j.foodchem.2016.05.126. Epub 2016 May 20.
• The effect of apple phenolics on the oxidative damage caused to myofibrillar proteins by an in vitro metal-catalyzed oxidation system was investigated. Three pure phenolic compounds (chlorogenic acid, (-)-epicatechin and phloridzin) and an apple peel extract were added to myofibrillar proteins in th
• PMID 27283697

• Detection of antibacterial activity of an enzymatic hydrolysate generated by processing rainbow trout by-products with trout pepsin.

• Wald M1, Schwarz K2, Rehbein H3, Bußmann B4, Beermann C5.
• Food chemistry.Food Chem.2016 Aug 15;205:221-8. doi: 10.1016/j.foodchem.2016.03.002. Epub 2016 Mar 2.
• Trout by-product hydrolysates, generated using trout pepsin, were characterized and studied in terms of their antibacterial effects against food contaminants and fish farming pathogens. After a hydrolysis time of 25min, the hydrolysates demonstrated inhibitory activity against several gram-positive
• PMID 27006234

• Probing the impact of quercetin-7-O-glucoside on influenza virus replication influence.

• Gansukh E1, Kazibwe Z1, Pandurangan M1, Judy G1, Kim DH2.
• Phytomedicine : international journal of phytotherapy and phytopharmacology.Phytomedicine.2016 Aug 15;23(9):958-67. doi: 10.1016/j.phymed.2016.06.001. Epub 2016 Jun 3.
• BACKGROUND: Influenza virus is still at large and seriously affects social welfare and health. Dianthus superbus is a well-known medicinal plant widely used in Mongolian and Chinese traditional medicine for anti-inflammatory purposes.PURPOSE: To investigate the influence of this novel herbal medicin
• PMID 27387404

Japanese Journal

• Opposing effects of IL-1β/COX-2/PGE2 pathway loop on islets in type 2 diabetes mellitus

• Wang Guanqiao,Ding Xuejie,Zhang Boya,Wang Zhiping,Wang Shusen,Shen Zhongyang,Liang Rui,Liu Tengli,Wang Le,Zou Jiaqi,Liu Na,Liu Yan,Cai Xiangheng,Liu Yaojuan
• Endocrine Journal, 2019
• … PGE2, the catalytic product of COX-2, downregulated the functional gene expression of <i>PDX1</i>, <i>NKX6.1</i>, and <i>MAFA</i> … Conversely, inhibition of COX-2 activity by a pharmaceutical inhibitor prevented the β-cell dysfunction induced by IL-1β. …
• NAID 130007650900

• Stability of Polyphenols under Alkaline Conditions and the Formation of a Xanthine Oxidase Inhibitor from Gallic Acid in a Solution at pH 7.4

• Honda Sari,Ishida Rika,Hidaka Kayo,Masuda Toshiya
• Food Science and Technology Research 25(1), 123-129, 2019
• … XO activity was significantly inhibited by the product produced from gallic acid in pH 7.4 solution. … The structural analysis of this reaction product revealed that a gallic acid dimer, purpurogallin-8-carboxylic acid, was formed and played a role in the resulting XO inhibitory activity.</p> …
• NAID 130007607026

• Meridianin C inhibits the growth of YD-10B human tongue cancer cells through macropinocytosis and the down-regulation of Dickkopf-related protein-3

• 野口 雅之,Nam-Sook Park,Yu-Kyoung Park,Mahesh Ramalingam,Anil Kumar Yadav,Hyo-Rim Cho,Victor Sukbong Hong,Kunal N. More,Jae-Hoon Bae,David Bishop-Bailey,Junko Kano,Masayuki NOGUCHI,Ik-Soon Jang,Kyung-Bok Lee,Jinho Lee,Jong-Soon Choi,Byeong-Churl Jang
• Journal of Cellular and Molecular Medicine 22(12), 5833-5846, 2018-12
• … Meridianin C is a marine natural product known for its anti‐cancer activity. … A role for DKK‐3 in regulating macropinocytosis in the YD‐10B cells was confirmed by siRNA knockdown of endogenous DKK‐3, which led to a partial accumulation of vacuoles and a reduction in cell proliferation, and by exogenous DKK‐3 overexpression, which resulted in a considerable inhibition of the meridianin C‐induced vacuole formation and decrease in cell survival. …
• NAID 120006582777

Related Links

• Types of Inhibition: Competitive Noncompetitive Uncompetitive ...

4 Examples: Competitive and Noncompetitive Inhibition LACTATE DEHYDROGENASE **NAD (oxidized form) R O NH2 C N H O HC O - 3 OH C O2 +H - 3 H pyruvate L-l ac te H+ NAD-OH O NH2 C N H R O INH BTORS: O C C O2

• Substrate and product inhibition kinetics in succinic acid ...

Abstract The inhibition of substrate and products on the growth of Actinobacillus succinogenes in fermentation using glucose as the major carbon source was studied. A. succinogenes tolerated up to 143 g/L glucose and cell growth ...

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★リンクテーブル★

リンク元	「生成物阻害」
関連記事	「product」「inhibition」

「生成物阻害」

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英

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同

product inhibition

関

[[]]

同

product inhibition

「product」

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• n.

• 産物、生成物、製品、結果、成果。(化学)生成物。(数学)積

関

accomplishment、achievement、consequence、outcome、output、result、resultant、sequence

　 　 　 　 　

「inhibition」

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• n.

• 1.抑止、抑制、阻止、禁止
• 2.抑止(阻止)するもの
• 3.(心理学)(衝動などの)抑制
• 4.(化)(化学反応の)抑制
• 5.(生物)(酵素の働きなどの)抑制、阻害