1. antipsychotic and antiemetic drug used to treat schizophrenia and to combat nausea and vomiting

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/03/08 12:25:43」(JST)

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English Journal

  • The Safety of Prochlorperazine in Children: A Systematic Review and Meta-Analysis.
  • Lau Moon Lin M1, Robinson PD2, Flank J1,3, Sung L4,5, Dupuis LL6,7,8.
  • Drug safety.Drug Saf.2016 Feb 16. [Epub ahead of print]
  • INTRODUCTION: Prochlorperazine is recommended for adults with breakthrough or refractory chemotherapy-induced nausea and vomiting (CINV). The objective of this review was to describe its safety in children when given for any indication to help define its role for CINV control in children.METHODS: El
  • PMID 26884326
  • Acute Treatment Therapies for Pediatric Migraine: A Qualitative Systematic Review.
  • Patniyot IR1,2, Gelfand AA1,2.
  • Headache.Headache.2016 Jan;56(1):49-70. doi: 10.1111/head.12746.
  • OBJECTIVE: We sought to conduct a qualitative systematic review to evaluate the safety and efficacy of available treatments for pediatric patients with migraine or benign primary headache in the emergency department, in an effort to inform future practice.METHODS: Scopus, Medline, and PubMed databas
  • PMID 26790849
  • Movement Disorders From the Use of Metoclopramide and Other Antiemetics in the Treatment of Migraine.
  • Wijemanne S1, Jankovic J1, Evans RW2.
  • Headache.Headache.2016 Jan;56(1):153-61. doi: 10.1111/head.12712. Epub 2015 Nov 17.
  • Nausea and vomiting are a frequent accompaniment of migraine and anti-nausea medications are frequently used in its management. The majority of anti-nausea medications that are used in migraine are dopamine receptor blocking agents and therefore have the potential to cause drug-induced movement diso
  • PMID 26573884

Japanese Journal

  • Incidence of Nausea and Vomiting Induced by Oxycodone Administered with Prochlorperazine in Japanese Cancer Patients
  • プロクロルペラジン(ノバミン<sup>®</sup>)による光線過敏型薬疹の1例
  • メルファラン連日・大量投与に伴う悪心・嘔吐に対する‌多剤併用制吐療法の後方視的検討

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Prochlorperazine (Compazine, Stemzine, Buccastem, Stemetil, Phenotil) is a dopamine (D2) receptor antagonist that belongs to the phenothiazine class of antipsychotic agents that are used for the antiemetic treatment of nausea and vertigo.
Department of Palliative Medicine, Osaka University Graduate School of Medicine. プロクロルペラジン(prochlorperazine). ポイント. ・本剤はドパミン D2 受容 体遮断作用を有し,延髄最後野にある化学受容体引き金帯. (chemoreceptor trigger zone:CTZ) ...

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