プリジノール
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- pridinol mesilate
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/07/02 08:04:44」(JST)
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Pridinol
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Systematic (IUPAC) name |
1,1-diphenyl-3-(piperidin-1-yl)propan-1-ol |
Clinical data |
AHFS/Drugs.com |
International Drug Names |
Pregnancy cat. |
? |
Legal status |
? |
Routes |
oral, parenteral |
Identifiers |
CAS number |
511-45-5 N |
ATC code |
M03BX03 |
PubChem |
CID 4904 |
DrugBank |
DB00945 |
ChemSpider |
4735 Y |
UNII |
9E75Q6SUUB Y |
ChEMBL |
CHEMBL404215 Y |
Chemical data |
Formula |
C20H25NO |
Mol. mass |
295.419 g/mol |
InChI
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InChI=1S/C20H25NO/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21/h1-2,4-7,10-13,22H,3,8-9,14-17H2 Y
Key:RQXCLMGKHJWMOA-UHFFFAOYSA-N Y
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N (what is this?) (verify)
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Pridinol is a muscle relaxant.
There is some evidence in one of Paul Janssen's first books that pridinol cannot simply be acylated to make a reverse ester of methadone. The reason for this is steric strain making the product unstable.
See also[edit]
- Trihexyphenidyl
- Gamfexidine
Skeletal muscle relaxants (M03)
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Peripherally acting
(primarily antinicotinic,
NMJ block) |
Non-depolarizing
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Curare alkaloids
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- Alcuronium
- Dimethyltubocurarine
- Tubocurarine
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4° ammonium agents
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- ultra-short duration: Gantacurium
- short duration: Mivacurium
- Chandonium
- intermediate duration: Atracurium
- Cisatracurium
- Fazadinium
- Rocuronium
- Vecuronium
- long duration: Doxacurium
- Dimethyltubocurarine
- Pancuronium
- Pipecuronium
- Laudexium
- Gallamine
- unsorted: Hexafluronium (Hexafluorenium)
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Depolarizing
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- Choline derivatives: Suxamethonium (Succinylcholine)
- Polyalkylene derivatives: Hexamethonium
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ACh release inhibitors
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Centrally acting |
Carbamic acid esters
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- Carisoprodol
- Cyclarbamate
- Difebarbamate
- Febarbamate
- Meprobamate
- Methocarbamol
- Phenprobamate
- Styramate
- Tybamate
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Benzodiazepines
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- Bentazepam
- Bromazepam
- Diazepam
- Clonazepam
- Flunitrazepam
- Lorazepam
- Nitrazepam
- Tetrazepam
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Nonbenzodiazepines
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Thienodiazepines
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Quinazolines
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Anticholinergics (Antimuscarinics)
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- Cyclobenzaprine
- Orphenadrine
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Other
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- Arbaclofen placarbil
- Baclofen
- Chlormezanone
- Chlorphenesin
- Chlorzoxazone
- Donepezil
- Eperisone
- Fenyramidol
- Flopropione
- GHB
- Mephenesin
- Mephenoxalone
- Metaxalone
- Phenibut
- Pridinol
- Promoxolane
- Quinine
- Thiocolchicoside
- Tizanidine
- Tolperisone
- Trazodone
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Directly acting |
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anat (h/n, u, t/d, a/p, l)/phys/devp/hist
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noco (m, s, c)/cong (d)/tumr, sysi/epon, injr
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English Journal
- Validation of simultaneous volumetric and HPLC methods for the determination of pridinol mesylate in raw material.
- Simionato LD1, Ferello L, Stamer S, Zubata PD, Segall AI.
- ISRN pharmaceutics.ISRN Pharm.2013 Oct 2;2013:540676. doi: 10.1155/2013/540676. eCollection 2013.
- Simple, sensitive, and economical simultaneous volumetric and HPLC methods for the determination of pridinol mesylate in raw material have been developed. The volumetric method is based on the reaction of pridinol with sodium lauryl sulphate in diluted sulphuric acid. Dimethyl yellow was used as ind
- PMID 24224103
- Development and validation of a dissolution test for meloxicam and pridinol mesylate from combined tablet formulation.
- Vignaduzzo SE1, Castellano PM, Kaufman TS.
- Indian journal of pharmaceutical sciences.Indian J Pharm Sci.2010 Mar;72(2):197-203. doi: 10.4103/0250-474X.65033.
- The association of meloxicam and pridinol is indicated for treating muscular contractures and low back pain. A dissolution test for the meloxicam-pridinol combined tablet formulation was developed and validated, using a suitable HPLC method for simultaneously quantitating both dissolved drugs. The o
- PMID 20838523
- Development and validation of an HPLC method for the determination of process-related impurities in pridinol mesylate, employing experimental designs.
- Bianchini RM1, Castellano PM, Kaufman TS.
- Analytica chimica acta.Anal Chim Acta.2009 Nov 10;654(2):141-7. doi: 10.1016/j.aca.2009.09.022. Epub 2009 Sep 20.
- A simple high performance liquid chromatographic method for the determination of process-related impurities in bulk drug of the central anticholinergic compound pridinol mesylate, has been developed and validated. Spectroscopically characterized synthetic impurities were used as standards. The chrom
- PMID 19854345
Related Links
- Pridinol. From Wikipedia, the free encyclopedia. Jump to: navigation, search ... There is some evidence in one of Paul Janssens first books that pridinol cannot simply be acylated to make a reverse ester of methadone. The reason for this is ...
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