WordNet

semisolid preparation (usually containing a medicine) applied externally as a remedy or for soothing an irritation (同)unction, unguent, balm, salve
a lightweight thermoplastic; used especially in packaging and insulation (同)polythene

PrepTutorEJDIC

軟こう,こう薬
ポリエチレン(《英》polythene)

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1. 肝斑 melasma
2. 偽髭毛嚢炎 pseudofolliculitis barbae
3. 肌の若返りのためのレーザーによる皮膚の再生 ablative laser resurfacing for skin rejuvenation
4. リウマチ性疾患におけるサイトカインネットワーク：治療の意味 cytokine networks in rheumatic diseases implications for therapy
5. 尋常性ざ瘡のための光治療、補助化学療法、およびその他の治療法 light based adjunctive and other therapies for acne vulgaris

English Journal

Physicochemical properties, in vitro release and skin permeation studies of a topical formulation of standardized pomegranate rind extract.

Mo J1, Kaewnopparat N2, Songkro S2, Panichayupakaranant P3, Reanmongkol W1.
Pakistan journal of pharmaceutical sciences.Pak J Pharm Sci.2015 Jan;28(1):29-36.
The aim of the present study was to develop a stable formulation containing standardized pomegranate rind extracts (SPRE) for topical use in the treatment of dermal diseases. Ellagic acid (EA) as the major active constituent of SPRE (not less than 13%) was quantified by HPLC as an indicator for stud
PMID 25553706

Calcipotriol delivery into the skin as emulgel for effective permeation.

Naga Sravan Kumar Varma V1, Maheshwari PV1, Navya M1, Reddy SC1, Shivakumar HG1, Gowda DV1.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society.Saudi Pharm J.2014 Dec;22(6):591-9. doi: 10.1016/j.jsps.2014.02.007. Epub 2014 Feb 25.
The objective of this work is to formulate and evaluate an emulgel containing calcipotriol for treatment of psoriasis. Emulgels have emerged as a promising drug delivery system for the delivery of hydrophobic drugs. Isopropyl alcohol and polyethylene glycol have been employed as permeation enhancers
PMID 25561873

Proniosome-derived niosomes for tacrolimus topical ocular delivery: in vitro cornea permeation, ocular irritation, and in vivo anti-allograft rejection.

Li Q1, Li Z2, Zeng W1, Ge S1, Lu H1, Wu C1, Ge L1, Liang D2, Xu Y3.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.Eur J Pharm Sci.2014 Oct 1;62:115-23. doi: 10.1016/j.ejps.2014.05.020. Epub 2014 Jun 3.
The objective of this study was to develop proniosome-derived niosomes for topical ophthalmic delivery of Tacrolimus (FK506). The FK506 loaded proniosomes containing poloxamer 188 and lecithin as surfactants, cholesterol as a stabilizer, and minimal amount of ethanol and trace water reconstituted to
PMID 24905830

Japanese Journal

Effect of Vehicles on Percutaneous Absorption of Bucladesine (Dibutyryl Cyclic AMP) in Normal and Damaged Rat Skin

真船英一,高橋雅行,高杉紀雄
Biological & pharmaceutical bulletin 18(11), 1539-1543, 1995-11-15
… Percutaneous absorption from aqueous solution or ointment was very low in intact skin. … In both damaged skin models, a better absorption profile was obtained with the polyethylene glycol (PEG) than the petrolatum ointment and DBcAMP was released continuously from the PEG ointment, indicating that this ointment is suitable for the treatment of ulcers of the skin. …
NAID 110003663313

単純ヘルペスウイルス感染３症例に対するアシクロビル軟膏の使用経験

由良義明,伊賀弘起,近藤康夫,原田耕志,辻本仁志,吉田秀夫,佐藤光信
日本口腔科学会雑誌 42(4), 745-751, 1993
… Two cases of primary herpes simplex virus type 1 (HSV-1) infection with facial skin lesions and one case with recurrent herpetic lesions in the perioral area were treated by acyclovir ointment in combination with oral or intravenous acyclovir. … Acyclovir ointment used in this theraphy was composed of acyclovir, paraffin, vaseline, polyethylene glycol, carboxymethyl cellulose, and sodiumpolyacryl acid. …
NAID 130004335446

高分子材料を用いた局所投与剤形

町田良治
藥學雜誌 113(5), 356-368, 1993
… Adriamycin ointment for local chemotherapy to breast cancer prepared using polyethylene glycol, ammonium polyacrylate and hydroxypropyl cellulose (HPC) according to an optimum formulation showed an excellent clinical effect in spite of a decreased drug content. …
NAID 110003649404

Related Links

マクロゴール軟膏

マクロゴール軟膏. 和名マクロゴール軟膏. 英文名 Macrogol Ointment. CAS. 別名ポリエチレングリコール軟膏 (105316)、Polyethylene glycol Ointment. 収載公定書局方（ JP17 )， USP/NF (28/23) ( Polyethylene glycol Ointment 組成は異なる) 用途基剤. 【マクロゴール400 】と【マクロゴール4000 】の混合物であるので、それらの項を参照。.

Polyethylene glycol ointment | Allergic Contact Dermatitis ...

Where is Polyethylene glycol ointment found? This ointment is found in topical medications used to treat mucosal surfaces such as skin, nose, lips, and ears. How can you avoid contact with Polyethylene glycol ointment? • 1,2

Formulation of Polyethylene Glycol ointment bases suitable ...

Attention has been focused on the suitability of PEG ointment bases in tropical and subtropical regions. Penetrometer studies were carried out at 33, 37 and 50 degrees C respectively. Penetrometer experiments indicate that the type and amount of PEG will greatly affect the penentration time, and a large number of selected PEGs showed softening in ...