WordNet
- perennial herb of East Indies to Polynesia and Australia; cultivated for its large edible root yielding Otaheite arrowroot starch (同)Indian arrowroot, Tacca leontopetaloides, Tacca pinnatifida
- rare form of dichromacy characterized by a lowered sensitivity to blue light resulting in an inability to distinguish blue and yellow (同)blue-blindness
- (ophthalmology) faulty refraction of light rays in the eye as in astigmatism or myopia
- the ratio of the circumference to the diameter of a circle; approximately equal to 3.14159265358979323846...
- the 16th letter of the Greek alphabet
PrepTutorEJDIC
- 〈C〉パイ(ギリシア語アルファベットの第16字Π,π;英語のP,pに相当) / 〈U〉円周率(記号はπ)
- ごちゃまぜの活字 / ごちゃまぜ,混乱
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/25 09:15:01」(JST)
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- 1. 脳脊髄液：疾患状態における検査の生理学および有用性 cerebrospinal fluid physiology and utility of an examination in disease states
- 2. 神経管欠損および脳室拡大を除く中枢神経系異常の出生前診断 prenatal diagnosis of cns anomalies other than neural tube defects and ventriculomegaly
- 3. 多発神経根症：脊柱管狭窄症、感染症、癌、および炎症性神経根症候群 polyradiculopathy spinal stenosis infectious carcinomatous and inflammatory nerve root syndromes
- 4. 固形腫瘍による軟髄膜転移の臨床的特徴および診断 clinical features and diagnosis of leptomeningeal metastases from solid tumors
- 5. 軟髄膜転移の治療（癌性髄膜炎） treatment of leptomeningeal metastases carcinomatous meningitis
English Journal
- Immune system disturbances in schizophrenia.
- Horváth S1, Mirnics K2.Author information 1Department of Psychiatry, Vanderbilt University, Nashville, Tennessee; Department of Psychiatry, University of Szeged, 6725 Szeged, Hungary.2Department of Psychiatry, Vanderbilt University, Nashville, Tennessee; Vanderbilt Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, Tennessee; Department of Psychiatry, University of Szeged, 6725 Szeged, Hungary. Electronic address: karoly.mirnics@vanderbilt.edu.AbstractEpidemiological, genetic, transcriptome, postmortem, peripheral biomarker, and therapeutic studies of schizophrenia all point to a dysregulation of both innate and adaptive immune systems in the disease, and it is likely that these immune changes actively contribute to disease symptoms. Gene expression disturbances in the brain of subjects with schizophrenia show complex, region-specific changes with consistently replicated and potentially interdependent induction of serpin peptidase inhibitor, clade A member 3 (SERPINA3) and interferon inducible transmembrane protein (IFITM) family transcripts in the prefrontal cortex. Recent data suggest that IFITM3 expression is a critical mediator of maternal immune activation. Because the IFITM gene family is primarily expressed in the endothelial cells and meninges, and because the meninges play a critical role in interneuron development, we suggest that these two non-neuronal cell populations might play an important role in the disease pathophysiology. Finally, we propose that IFITM3 in particular might be a novel, appealing, knowledge-based drug target for treatment of schizophrenia.
- Biological psychiatry.Biol Psychiatry.2014 Feb 15;75(4):316-23. doi: 10.1016/j.biopsych.2013.06.010. Epub 2013 Jul 25.
- Epidemiological, genetic, transcriptome, postmortem, peripheral biomarker, and therapeutic studies of schizophrenia all point to a dysregulation of both innate and adaptive immune systems in the disease, and it is likely that these immune changes actively contribute to disease symptoms. Gene express
- PMID 23890736
- The new food package and breastfeeding outcomes among women, infants, and children participants in los angeles county.
- Langellier BA, Chaparro MP, Wang MC, Koleilat M, Whaley SE.Author information At the time of the study, Brent A. Langellier and M. Pia Chaparro were with and May C. Wang is with the Department of Community Health Sciences, Fielding School of Public Health, University of California, Los Angeles. At the time of the study, Maria Koleilat was with and Shannon E. Whaley is with Public Health Foundation Enterprises, Special Supplemental Nutrition Program for Women, Infants, and Children Program, Los Angeles, CA.AbstractObjectives. We assessed the effect of the new Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) food package, implemented in October 2009, on breastfeeding outcomes among a predominately Latina sample of WIC participants in Los Angeles County, California. Methods. We used data from 5020 WIC participants who were interviewed in a series of repeated cross-sectional surveys conducted in 2005, 2008, and 2011. Participants were randomly selected from Los Angeles County residents who received WIC services during those years. Results. Consistent with the WIC population in Los Angeles, participants were mostly Latina and had low levels of income and education; more than half were foreign-born. We found small but significant increases from pre- to postimplementation of the new WIC food package in prevalence of prenatal intention to breastfeed and breastfeeding initiation, but no changes in any breastfeeding at 3 and 6 months. The prevalence of exclusive breastfeeding at 3 and 6 months roughly doubled, an increase that remained large and significant after adjustment for other factors. Conclusions. The new food package can improve breastfeeding outcomes in a population at high risk for negative breastfeeding outcomes.
- American journal of public health.Am J Public Health.2014 Feb;104 Suppl 1:S112-8. doi: 10.2105/AJPH.2013.301330. Epub 2013 Dec 19.
- Objectives. We assessed the effect of the new Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) food package, implemented in October 2009, on breastfeeding outcomes among a predominately Latina sample of WIC participants in Los Angeles County, California. Methods. We used
- PMID 24354843
- The Stress-response protein prostate-associated gene 4, interacts with c-Jun and potentiates its transactivation.
- Rajagopalan K1, Qiu R2, Mooney SM1, Rao S1, Shiraishi T1, Sacho E2, Huang H3, Shapiro E3, Weninger KR4, Kulkarni P5.Author information 1Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.2Department of Physics, North Carolina State University, Raleigh, NC 27695, USA.3Department of Urology, New York University School of Medicine, New York, NY 10016, USA.4Department of Physics, North Carolina State University, Raleigh, NC 27695, USA. Electronic address: krwening@ncsu.edu.5Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address: pkulkar4@jhmi.edu.AbstractThe Cancer/Testis Antigen (CTA), Prostate-associated Gene 4 (PAGE4), is a stress-response protein that is upregulated in prostate cancer (PCa) especially in precursor lesions that result from inflammatory stress. In cells under stress, translocation of PAGE4 to mitochondria increases while production of reactive oxygen species decreases. Furthermore, PAGE4 is also upregulated in human fetal prostate, underscoring its potential role in development. However, the proteins that interact with PAGE4 and the mechanisms underlying its pleiotropic functions in prostatic development and disease remain unknown. Here, we identified c-Jun as a PAGE4 interacting partner. We show that both PAGE4 and c-Jun are overexpressed in the human fetal prostate; and in cell-based assays, PAGE4 robustly potentiates c-Jun transactivation. Single-molecule Förster resonance energy transfer experiments indicate that upon binding to c-Jun, PAGE4 undergoes conformational changes. However, no interaction is observed in presence of BSA or unilamellar vesicles containing the mitochondrial inner membrane diphosphatidylglycerol lipid marker cardiolipin. Together, our data indicate that PAGE4 specifically interacts with c-Jun and that, conformational dynamics may account for its observed pleiotropic functions. To our knowledge, this is the first report demonstrating crosstalk between a CTA and a proto-oncogene. Disrupting PAGE4/c-Jun interactions using small molecules may represent a novel therapeutic strategy for PCa.
- Biochimica et biophysica acta.Biochim Biophys Acta.2014 Feb;1842(2):154-63. doi: 10.1016/j.bbadis.2013.11.014. Epub 2013 Nov 18.
- The Cancer/Testis Antigen (CTA), Prostate-associated Gene 4 (PAGE4), is a stress-response protein that is upregulated in prostate cancer (PCa) especially in precursor lesions that result from inflammatory stress. In cells under stress, translocation of PAGE4 to mitochondria increases while productio
- PMID 24263171
Japanese Journal
- 遺言による財団設立とpia causa : シュテーデル美術館事件とローマ法源
- 野田 龍一
- 福岡大学法学論叢 58(4), 671-725, 2014-03
- NAID 110009752378
- 21世紀の保健医療福祉専門職学生を育てる : 国際交流により強化された多職種連携教育の実践
- 古西 勇,押木 利英子,Carmelo C.Cunanan,Pia Vanessa C.Basilio
- 新潟医療福祉学会誌 13(1), 78-78, 2013-10
- NAID 120005404512
- Prominent Charge-Transfer State at \alpha-Sexithiophene/C
- Takahashi Yousuke,Yonezawa Kouhei,Kamioka Hayato,Yasuda Takeshi,Han Liyuan,Moritomo Yutaka
- J Phys Soc Jpn 82(6), 063709-063709-4, 2013-06-15
- … We observed sharp and intense photoinduced absorption (PIA) at 1.2 eV and ascribed it to the charge-transfer (CT) state. …
- NAID 150000107644
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