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English Journal
- Defining biomarkers to predict sensitivity to PI3K/Akt/mTOR pathway inhibitors in breast cancer.
- Gonzalez-Angulo AM, Blumenschein GR Jr.SourceDepartment of Breast Medical Oncology, The University of Texas, M.D. Anderson Cancer Center, Houston, TX, USA; Department Systems Biology, The University of Texas, M.D. Anderson Cancer Center, Houston, TX, USA. Electronic address: agonzalez@mdanderson.org.
- Cancer treatment reviews.Cancer Treat Rev.2013 Jun;39(4):313-20. doi: 10.1016/j.ctrv.2012.11.002. Epub 2012 Dec 6.
- BACKGROUND: Identification and validation of biomarkers is increasingly important for the integration of novel targeted agents in the treatment of cancer. The phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway represents a promising therapeutic target in breast car
- PMID 23218708
- Independent and combined effects of acute physiological hyperglycaemia and hyperinsulinaemia on metabolic gene expression in human skeletal muscle.
- Tsintzas K, Norton L, Chokkalingam K, Nizamani N, Cooper S, Stephens F, Billeter R, Bennett A.SourceSchool of Biomedical Sciences, Nottingham University Medical School, Queens Medical Centre, Nottingham NG7 2UH, UK. Kostas.Tsintzas@nottingham.ac.uk
- Clinical science (London, England : 1979).Clin Sci (Lond).2013 Jun;124(11):675-84. doi: 10.1042/CS20120481.
- Physiological hyperglycaemia and hyperinsulinaemia are strong modulators of gene expression, which underpins some of their well-known effects on insulin action and energy metabolism. The aim of the present study was to examine whether acute in vivo exposure of healthy humans to hyperinsulinaemia and
- PMID 23316693
Japanese Journal
- Anandamide enhances expression of heat shock protein 72 to protect against ischemia?reperfusion injury in rat heart
- Li Qian,Shi Min,Li Bo
- The journal of physiological sciences 63(1), 47-53, 2013-01
- NAID 40019538830
- Cellular and Physiological Functions of Phosphoinositide-Metabolizing Enzymes
- Fujii Makoto,Kita Satomi,Horie Ichiro,Gotoh Yusuke,Iwamoto Takahiro
- 福岡大学医学紀要 39(3/4), 281-287, 2012-12
- NAID 110009494963
Related Links
- In enzymology, a phosphatidylinositol-4,5-bisphosphate 3-kinase (EC 2.7.1.153) is an enzyme that catalyzes the chemical reaction ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5 ...
- phos·pha·ti·dyl·in·o·si·tol 4,5-·bis·phos·phate (PIP 2, PtdIns(4,5)P 2), phosphatidylinositol with two additional sites of phosphorylation; an important constituent of cell membrane phospholipids as well as a precursor of the second ...
★リンクテーブル★
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- 英
- phosphatidylinositol 4
- 関
- ホスファチジルイノシトール二リン酸、ホスファチジルイノシトール-4,5-二リン酸
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- 英
- phosphatidylinositol 4
- 関
- ホスファチジルイノシトール二リン酸、ホスファチジルイノシトール2リン酸
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ホスファチジルイノシトール二リン酸、ホスファチジルイノシトール2リン酸、ホスファチジルイノシトール-4,5-二リン酸
- 関
- phosphatidylinositol 4,5-biphosphate、phosphatidylinositol 4,5-diphosphate、PIP2、PtdIns-4,5-P2
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ホスファチジルイノシトール-4-キナーゼ
- 関
- 1-phosphatidylinositol 4-kinase、PI 4-kinase、PI4K、PtdIns 4-kinase
[★]
1-ホスファチジルイノシトール-4-キナーゼ
- 関
- phosphatidylinositol 4-kinase、PI 4-kinase、PtdIns 4-kinase
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ホスファチジルイノシトール