ペルフェナジン
WordNet
- a salt or ester of maleic acid; used as a nontricyclic antidepressant drug for psychomotor activation
- tranquilizer and antidepressant (trade name Triavil) sometimes used as an antiemetic for adults (同)Triavil
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English Journal
- Effect of perphenazine enanthate in Pyrenean chamois (Rupicapra pyrenaica).
- Marco I1, Cabezón O2, Mentaberre G2, Fernández-Sirera L2, Casas-Díaz E2, Fernandez-Aguilar X2, López-Olvera JR2, Serrano E2, Navarro-Gonzalez N2, Lavín S2, Manteca X3.Author information 1Servei d'Ecopatologia de Fauna Salvatge, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193-Bellaterra, Spain. Ignasi.Marco@uab.cat2Servei d'Ecopatologia de Fauna Salvatge, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193-Bellaterra, Spain.3Departament de Ciència Animal i dels Aliments, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193-Bellaterra, Spain.AbstractPerphenazine enanthate was used to allow adaptation to captivity in 11 Pyrenean chamois (Rupicapra pyrenaica). At the time of capture, all animals received 0.10 mg/kg of acepromazine maleate and 2.5 mg/kg of perphenazine enanthate intramuscularly. The effect was evaluated by means of three behaviors: alertness, defecation, and flight distance. The tranquilization and lack of fear of humans of all animals were determined and the usefulness of this long-acting tranquilizer for chamois adaptation to captivity was confirmed.
- Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.J Zoo Wildl Med.2013 Dec;44(4):1083-5.
- Perphenazine enanthate was used to allow adaptation to captivity in 11 Pyrenean chamois (Rupicapra pyrenaica). At the time of capture, all animals received 0.10 mg/kg of acepromazine maleate and 2.5 mg/kg of perphenazine enanthate intramuscularly. The effect was evaluated by means of three behaviors
- PMID 24450074
- Preliminary studies on phenothiazine-mediated reversal of multidrug resistance in mouse lymphoma and COLO 320 cells.
- Pajak B1, Molnar J, Engi H, Orzechowski A.Author information 1Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw Agricultural University, ul. Nowoursynowska 159, 02-776 Warsaw, Poland.AbstractThe ability of phenothiazine derivatives to inhibit the transport activity of P-glycoprotein in resistant mouse lymphoma and MDR/COLO 320 cells was studied. A rhodamine 123 efflux from the above-mentioned neoplastic cells in the presence of tested compounds was examined by flow cytometry. Two of the phenothiazine derivatives, namely perphenazine and prochlorperazine dimaleate, proved to be effective inhibitors of the rhodamine efflux. Other tested phenothiazine derivatives (promethazine hydrochloride, oxomemazine, methotrimeprazine maleate, trifluoropromazine hydrochloride, trimeprazine) also modulated the intracellular drug accumulation in both resistant cell lines, however, they exerted additional cytotoxic effects. The differences observed between the effects of the test compounds on intracellular drug accumulation could be the outcome of differences in phenothiazine's chemical structure, which is crucial for drug-cell membrane interactions. The results of this study provide information about a new group of compounds that offer promise in multidrug resistance reversal in tumor cells.
- In vivo (Athens, Greece).In Vivo.2005 Nov-Dec;19(6):1101-4.
- The ability of phenothiazine derivatives to inhibit the transport activity of P-glycoprotein in resistant mouse lymphoma and MDR/COLO 320 cells was studied. A rhodamine 123 efflux from the above-mentioned neoplastic cells in the presence of tested compounds was examined by flow cytometry. Two of the
- PMID 16277030
- Coloration of phenothiazines with metal-containing drugs.
- Hosomi K1, Okuno A, Umetani Y, Araya T, Matsuyama K, Haginaka J, Mifune M, Saito Y.Author information 1Department of Pharmacy, Nishi-Kobe Medical Center, Japan. khosomi-ind@umin.ac.jpAbstractWe studied the color change of phenothiazines and metal-containing drugs after compound formation, followed by use of FT-Raman spectrocopy to observe any structural changes in them. When 6 phenothiazines (thioridazine hydrochloride, prochlorperazine maleate, levomepromazine maleate, chlorpromazine phenolphthalinate, fluphenazine maleate and perphenazine fendiate) formed compounds with natural aluminum silicate, the color change was accompanied by a shift of FT-Raman signals. These changes could be attributed to the structural changes of phenothiazines. This present observation can be then used in advance to avoid coloration of phenothiazines during preparative procedures with metal-containing drugs such as antacids.
- Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.Yakugaku Zasshi.2004 Sep;124(9):587-98.
- We studied the color change of phenothiazines and metal-containing drugs after compound formation, followed by use of FT-Raman spectrocopy to observe any structural changes in them. When 6 phenothiazines (thioridazine hydrochloride, prochlorperazine maleate, levomepromazine maleate, chlorpromazine p
- PMID 15340180
Japanese Journal
- Coloration of Phenothiazines with Metal-containing Drugs
- 細見 光一,奥野 昌宏,梅谷 義晴 [他],顕谷 昭久,松山 賢治,萩中 淳,御船 正樹,斎藤 寛
- 藥學雜誌 124(9), 587-598, 2004-09-01
- … When 6 phenothiazines (thioridazine hydrochloride, prochlorperazine maleate, levomepromazine maleate, chlorpromazine phenolphthalinate, fluphenazine maleate and perphenazine fendiate) formed compounds with natural aluminum silicate, the color change was accompanied by a shift of FT-Raman signals. …
- NAID 110003614990
- EFFECT OF PHENOTHIAZINES, DISODIUM ETHYLENEDIAMINE-TETRAACETIC ACID AND DIETHYL MALEATE ON IN VITRO RAT COLONIC TRANSPORT OF CEFMETAZOLE AND INULIN
- SUZUKA TAKUMI,FURUYA ATSUSHI,KAMADA AKIRA,NISHIHATA TOSHIAKI
- Journal of pharmacobio-dynamics 10(2), 63-71, 1987-02-00
- … Phenothiazines as well as disodium ethylenediaminetetraacetic acid increased the transport of cefmetazole and inulin, probably via the paracellular route, while diethyl maleate increased the transport of only cefmetazole, probably via the intracellular route. …
- NAID 110003636736
Related Links
- ペルフェナジンマレイン酸塩(Perphenazine maleate)の検索ならお薬検索QLife(キューライフ)。お医者さんが処方する処方薬と、薬局で買える市販薬(OTC)、の効果と副作用、写真、添付文書、保管方法等を掲載。商品名だけでなく一般名や ...
- Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on 'small' chemical compounds. ... ChEBI The database and ontology of Chemical Entities of Biological Interest
Related Pictures
★リンクテーブル★
[★]
- 英
- perphenazine
- ラ
- perphenazinum
- 同
- クロルピプラジン chlorpiprazine
- 化
- マレイン酸ペルフェナジン perphenazine maleate perphenazini maleas
- 商
- トリオミン、トリラホン Trilafon、ピーゼットシー
[★]
- 関
- perphenazine、perphenazine hydrochloride、perphenazine maleate
[★]
- 関
- perphenazine、perphenazine fendizoate、perphenazine maleate
[★]
マレイン酸、マレイン酸塩、マレイン酸エステル
- 関
- maleic acid