WordNet

an enzyme that catalyzes its substrate to an isomeric form

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1. 骨形成不全症：臨床的特徴および診断 osteogenesis imperfecta clinical features and diagnosis
2. Maintenance immunosuppressive therapy in renal transplantation in adults
3. 関節リウマチの病因 pathogenesis of rheumatoid arthritis
4. リウマチ性血管炎の臨床症状および診断 clinical manifestations and diagnosis of rheumatoid vasculitis
5. 研究用生物学的マーカーによる関節リウマチの診断および評価ま investigational biologic markers in the diagnosis and assessment of rheumatoid arthritis

English Journal

Peptidyl prolyl isomerase Pin1-inhibitory activity of d-glutamic and d-aspartic acid derivatives bearing a cyclic aliphatic amine moiety.

Nakagawa H1, Seike S2, Sugimoto M2, Ieda N2, Kawaguchi M2, Suzuki T3, Miyata N2.
Bioorganic & medicinal chemistry letters.Bioorg Med Chem Lett.2015 Dec 1;25(23):5619-24. doi: 10.1016/j.bmcl.2015.10.033. Epub 2015 Oct 22.
Pin1 is a peptidyl prolyl isomerase that specifically catalyzes cis-trans isomerization of phosphorylated Thr/Ser-Pro peptide bonds in substrate proteins and peptides. Pin1 is involved in many important cellular processes, including cancer progression, so it is a potential target of cancer therapy.
PMID 26508545

Vaccine potential of bacterial macrophage infectivity potentiator (MIP)-like peptidyl prolyl cis/trans isomerase (PPIase) proteins.

Humbert MV1, Almonacid Mendoza HL1, Jackson AC1, Hung MC1, Bielecka MK1, Heckels JE1, Christodoulides M1.
Expert review of vaccines.Expert Rev Vaccines.2015 Dec;14(12):1633-49. doi: 10.1586/14760584.2015.1095638. Epub 2015 Oct 15.
Peptidyl prolyl cis/trans isomerases (PPIases) are a superfamily of proteins ubiquitously distributed among living organisms, which function primarily to assist the folding and structuring of unfolded and partially folded polypeptide chains and proteins. In this review, we focus specifically on the
PMID 26468663

Japanese Journal

Peptidyl-prolyl cis-trans isomerase xFKBP1B induces ectopic secondary axis and is involved in eye formation during Xenopus embryogenesis

TERUKINA Goro,YOSHIDA Yoko,TAKAHASHI Nobuhiro
Development, growth & differentiation 53(1), 55-68, 2011-01-01
NAID 10027899296

Related Links

Peptidylprolyl isomerase A - Wikipedia, the free encyclopedia

This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. The encoded protein ...

Prolyl isomerase - Wikipedia, the free encyclopedia

Prolyl isomerase (also known as peptidylprolyl isomerase or PPIase) is an enzyme (EC 5.2.1.8) found in both prokaryotes and eukaryotes that interconverts the cis and trans isomers of peptide bonds with the amino acid proline. Proline has an ...