WordNet

any plant of the family Palmae having an unbranched trunk crowned by large pinnate or palmate leaves (同)palm tree
a linear unit based on the length or width of the human hand
the inner surface of the hand from the wrist to the base of the fingers (同)thenar
abnormal redness of the skin resulting from dilation of blood vessels (as in sunburn or inflammation)
relating to the palm of the hand or the sole of the foot; "the volar surface"; "the palmar muscle" (同)volar

PrepTutorEJDIC

(人動物の)『手のひら』;(手袋の)手のひらの部分 / パーム(手のひらの幅を基準にした長さ;8‐10`) / …‘を'手で殖れる,手の中に隠す
(また『palm tree』)ヤシ,シュロ(ヤシ科の植物) / (昔勝利・成功などの印として用いた)シュロの葉(枝)
紅斑(こうはん)(炎症などにより皮膚が異常に赤くなること)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/17 13:06:41」(JST)

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Palmar erythema is reddening of the palms at the thenar and hypothenar eminences.^[1]^:139

Causes

It is associated with various physiological as well as pathological changes, or may be a normal finding:

Portal hypertension
Chronic liver disease (including chronic hepatitis^[2])
Pregnancy
Polycythemia
Thyrotoxicosis
Rheumatoid Arthritis (especially in patients with polycythaemia)^[3]
Eczema and Psoriasis
Deep telangiectasias
Coxsackievirus A infection (Hand, foot and mouth disease)^[4]
Rocky Mountain Spotted Fever^[4]
Secondary Syphilis^[4]
Kawasaki disease

Because circulating levels of estrogen increase in both cirrhosis and pregnancy, estrogen was thought to be the cause for the increased vascularity. More recently, nitric oxide has been implicated in the pathogenesis of palmar erythema.^{[citation needed]}

References

^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
^ Basic pathology 8th edition p 646
^ Saario R, Kalliomaki JL (Dec 1985), "Palmar erythema in rheumatoid arthritis", Clin Rheumatol. 4 (4): 449–51, doi:10.1007/BF02031898, PMID 3830522
^ ^a ^b ^c Le T, Bhushan V, Vasan N (2010), First Aid for the USMLE Step 1, p. 156, mhid: 0-07-163340

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UpToDate Contents

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1. 成人における肝硬変：病態、臨床症状、および診断 cirrhosis in adults etiologies clinical manifestations and diagnosis
2. ウィルソン病：臨床症状、診断、および自然史 wilson disease clinical manifestations diagnosis and natural history
3. 妊娠中の肌、髪、爪、粘膜 the skin hair nails and mucous membranes during pregnancy
4. 関節リウマチの臨床症状 clinical manifestations of rheumatoid arthritis
5. 不完全（非定型）川崎病 incomplete atypical kawasaki disease

English Journal

[Acrokeratosis paraneoplastica Bazex 6 years prior to diagnosis of gastric cancer].

Kofler L1, Kofler H.
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete.Hautarzt.2015 Jan 13. [Epub ahead of print]
BACKGROUND: Bazex's syndrome is a rare paraneoplasia that is usually associated with cancer.DIAGNOSIS: Characteristic for the disease are diffuse, psoriasis-like, acral erythema, distal hyperkeratosis and onychodystrophy. Differential diagnoses comprise psoriasis, eczema and tinea.CASE REPORT: We pr
PMID 25578303

Cutaneous drug eruption induced by antihistamines.

Viñas M1, Castillo MJ, Hernández N, Ibero M.
Clinical and experimental dermatology.Clin Exp Dermatol.2014 Dec;39(8):918-20. doi: 10.1111/ced.12445.
Topical application of antihistamines commonly leads to sensitization for patients, but systemic administration of antihistamines rarely induces allergic hypersensitivity, which is mainly linked to phenothiazine-derived and piperazine-derived compounds. We report a 70-year-old woman whose medical hi
PMID 25394293

Enhanced skin toxicity associated with the combination of clofarabine plus cytarabine for the treatment of acute leukemia.

Zhang B1, Bolognia J, Marks P, Podoltsev N.
Cancer chemotherapy and pharmacology.Cancer Chemother Pharmacol.2014 Aug;74(2):303-7. doi: 10.1007/s00280-014-2504-y. Epub 2014 Jun 8.
PURPOSE: Skin toxicity is associated with a number of different chemotherapeutic agents used to treat acute leukemias. The term "toxic erythema of chemotherapy" (TEC) has been coined to describe a spectrum of skin findings, ranging from palmar-plantar erythrodysesthesia to erythema of major body fol
PMID 24908437

Japanese Journal

抗がん薬による皮膚有害事象の治療：緩和医療の中の皮膚科医の位置づけ

松村由美
Skin Cancer 26(3), 294-300, 2011
　分子標的薬は高頻度に皮膚有害事象を生じる。マルチキナーゼ阻害薬による手足症候群や手掌・足底発赤知覚不全症候群と呼ばれる手足の紅斑は，著明な疼痛と日常生活動作の低下をもたらす。そのために，キナーゼ阻害薬治療中の相当数の患者は，薬剤の中止を選択している現状がある。これらの皮膚症状は強力なステロイド外用薬や適切な靴の選択，正しいフットケアにてコントロール可能である。義肢装具士に依頼して靴を作成してもら …
NAID 130002149382