- 関
- oxiconazole
WordNet
- any compound containing the nitrate group (such as a salt or ester of nitric acid)
- treat with nitric acid, so as to change an organic compound into a nitrate; "nitroglycerin is obtained by nitrating glycerol"
PrepTutorEJDIC
- 硝酸塩 / 硝酸塩類化学肥料
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/30 20:48:25」(JST)
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Oxiconazole
|
Systematic (IUPAC) name |
(E)-[1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethylidene][(2,4-dichlorophenyl)methoxy]amine
|
Clinical data |
Trade names |
Oxistat |
AHFS/Drugs.com |
monograph |
MedlinePlus |
a689004 |
Identifiers |
CAS Registry Number |
64211-46-7 Y |
ATC code |
D01AC11 G01AF17 |
PubChem |
CID: 5361463 |
DrugBank |
DB00239 Y |
ChemSpider |
4514745 Y |
UNII |
RQ8UL4C17S Y |
KEGG |
D00885 Y |
ChEBI |
CHEBI:7825 N |
ChEMBL |
CHEMBL1262 N |
Chemical data |
Formula |
C18H13Cl4N3O |
Molecular mass |
429.126 g/mol |
SMILES
-
Clc3ccc(/C(=N\OCc1ccc(Cl)cc1Cl)Cn2ccnc2)c(Cl)c3
|
InChI
-
InChI=1S/C18H13Cl4N3O/c19-13-2-1-12(16(21)7-13)10-26-24-18(9-25-6-5-23-11-25)15-4-3-14(20)8-17(15)22/h1-8,11H,9-10H2/b24-18- Y
-
Key:QRJJEGAJXVEBNE-MOHJPFBDSA-N Y
|
N (what is this?) (verify) |
Oxiconazole (U.S.: Oxistat, Canada: Oxizole) is an antifungal medication typically administered in a cream or lotion to treat skin infections, such as athlete's foot, jock itch and ringworm. It can also be prescribed to treat the skin rash known as tinea versicolor, caused by systemic yeast overgrowth (Candida spp.).
See also
References
External links
- MedlinePlus - Oxiconazole
Antifungals (D01 and J02)
|
|
Wall/
membrane |
Ergosterol
inhibitors |
Azoles
(lanosterol 14
alpha-demethylase inhibitors) |
Imidazoles |
- Topical: bifonazole
- butoconazole
- chlormidazole
- clotrimazole#
- croconazole
- econazole
- fenticonazole
- ketoconazole
- isoconazole
- miconazole#
- neticonazole
- omoconazole
- oxiconazole
- sertaconazole
- sulconazole
- tioconazole
|
|
Triazoles |
- Topical: (fluconazole#, fosfluconazole
- terconazole)
- Systemic: (fluconazole
- hexaconazole
- isavuconazole
- itraconazole
- posaconazole
- voriconazole)
|
|
Thiazoles |
|
|
|
Polyene antimycotics
(ergosterol binding) |
- Topical: (hamycin
- natamycin
- nystatin#)
Systemic: (amphotericin B#, hamycin)
|
|
Allylamines
(squalene monooxygenase
inhibitors) |
- Topical: (amorolfine
- butenafine
- naftifine
- terbinafine)
Systemic: terbinafine
|
|
|
β-glucan synthase
inhibitors |
- echinocandins (anidulafungin
- caspofungin
- micafungin)
|
|
|
Intracellular |
Pyrimidine analogues/
thymidylate synthase inhibitors |
|
|
Mitotic inhibitors |
|
|
Aminoacyl tRNA synthetase inhibitors |
|
|
|
Others |
- bromochlorosalicylanilide
- methylrosaniline
- tribromometacresol
- undecylenic acid
- polynoxylin
- chlorophetanol
- chlorphenesin
- ticlatone
- sulbentine
- ethylparaben
- haloprogin
- salicylic acid
- selenium disulfide#
- ciclopirox
- amorolfine
- dimazole
- tolnaftate
- tolciclate
- sodium thiosulfate#
- Whitfield's ointment#
- potassium iodide#
- taurolidine
- tea tree oil
- citronella oil
- lemon grass
- orange oil
- patchouli
- lemon myrtle
- PCP: pentamidine
- dapsone
- atovaquone
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
Index of fungal disease
|
|
Description |
|
|
Disease |
|
|
Treatment |
|
|
|
Gynecological anti-infectives and antiseptics (G01)
|
|
Antibiotics |
- Candicidin
- Chloramphenicol
- Hachimycin
- Oxytetracycline
- Carfecillin
- Mepartricin
- Clindamycin
- Pentamycin
|
|
Arsenic compounds |
|
|
Quinoline derivatives |
- Diiodohydroxyquinoline
- Clioquinol
- Chlorquinaldol
- Dequalinium
- Broxyquinoline
- Oxyquinoline
|
|
Organic acids |
- Lactic acid
- Acetic acid
- Ascorbic acid
|
|
Sulfonamides |
|
|
Antifungals |
Imidazoles |
- Metronidazole
- Clotrimazole
- Miconazole
- Econazole
- Ornidazole
- Isoconazole
- Tioconazole
- Ketoconazole
- Fenticonazole
- Azanidazole
- Propenidazole
- Butoconazole
- Omoconazole
- Oxiconazole
- Flutrimazole
|
|
Triazoles |
|
|
Polyenes |
- Nystatin
- Natamycin
- Amphotericin B
|
|
Other |
- Ciclopirox
- Methylrosaniline
|
|
|
Other |
- Clodantoin
- Inosine
- Policresulen
- Nifuratel
- Furazolidone
- Povidone-iodine
- Protiofate
- Lactobacillus fermentum
- Copper usnate
|
|
Index of reproductive medicine
|
|
Description |
- Anatomy
- Physiology
- Development
- sex determination and differentiation
|
|
Disease |
- Infections
- Congenital
- Neoplasms and cancer
- male
- female
- gonadal
- germ cell
- Other
- Symptoms and signs
|
|
Treatment |
- Procedures
- Drugs
- benign prostatic hypertrophy
- erectile dysfunction and premature ejaculation
- sexual dysfunction
- infection
- hormones
- androgens
- estrogens
- progestogens
- GnRH
- prolactin
- Assisted reproduction
- Birth control
|
|
|
UpToDate Contents
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English Journal
- Antifungal susceptibilities of Candida species isolated from the patients with vaginal candidiasis.
- Nagashima M1, Yamagishi Y1, Mikamo H2.
- Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.J Infect Chemother.2016 Feb;22(2):124-6. doi: 10.1016/j.jiac.2015.08.008. Epub 2015 Nov 25.
- There have been the current Japanese data on susceptibility testing for Candida isolates from vaginal candidiasis. The in vitro activities of therapeutic antifungal drugs for vulvovaginal candidiasis (VVC); miconazole (MCZ), itraconazole (ITCZ), fluconazole (FLCZ), clotrimazole (CTZ), oxiconazole (
- PMID 26627336
- [In vitro antifungal susceptibility profile of Scopulariopsis brevicaulis isolated from onychomycosis].
- Carrillo-Muñoz AJ1, Tur-Tur C, Cárdenes D, Rojas F, Giusiano G.
- Revista española de quimioterapia : publicación oficial de la Sociedad Española de Quimioterapia.Rev Esp Quimioter.2015 Aug;28(4):210-3.
- We studied the in vitro antifungal activity profile of amorolfine (AMR), bifonazole (BFZ), clotrimazole (CLZ), econazole (ECZ), fluconazole (FNZ), itraconazole (ITZ), ketoconazole (KTZ), miconazole (MNZ), oxiconazole (OXZ), tioconazole (TCZ) and terbinafine (TRB) against 26 clinical isolates of Scop
- PMID 26200030
- [The impact of concentrations of nitric oxide and activity of oxistat on development of inflammatory alterations in vascular wall].
- NIkitina VV, Zakharova NB, Gladilin GP, Korshunov GV.
- Klinicheskaia laboratornaia diagnostika.Klin Lab Diagn.2014 May;(5):11-3.
- The analysis was applied to results of study of impact of concentrations of nitric oxide and activity of oxistat on development of alterations in vascular wall in patients with different stages of atherosclerosis of vessels. The priority indicators according established marker are revealed.
- PMID 25338456
Japanese Journal
- 走査電子顕微鏡法によるイミダゾール系抗真菌剤oxiconazole nitrateの白癬菌形態に及ぼす影響.
- Mode of antifungal action of oxiconazole nitrate toward Candida albicans
- モルモットの白癬モデルに対する新規イミダゾール誘導体oxiconazole nitrateクリーム剤の治療効果
Related Links
- Consumer information about the medication OXICONAZOLE NITRATE - TOPICAL (Oxistat), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription ...
- OXISTAT ® Cream and OXISTAT ® Lotion are indicated for the topical treatment of the following dermal infections: tinea pedis, tinea cruris, and tinea corporis due to Trichophyton rubrum, Trichophyton mentagrophytes, or Epidermophyton floccosum
Related Pictures
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★リンクテーブル★
[★]
- 英
- oxiconazole
- 化
- 硝酸オキシコナゾール oxiconazole nitrate
- 商
- オキナゾール、オキコナール
[★]
硝酸、(化合物)硝酸塩、硝酸薬、ナイトレート、ニトロ化する
- 関
- HNO3、nitration、nitric acid
[★]
オキシコナゾール
- 関
- oxiconazole nitrate