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1. 過敏性腸症候群に対するアロセトロン塩酸塩（Lotronex） alosetron hydrochloride lotronex for irritable bowel syndrome
2. 変形性関節症の初回薬物療法 initial pharmacologic therapy of osteoarthritis
3. クリンダマイシン：概要 clindamycin an overview
4. 成人における急性咽頭炎の対症療法 symptomatic treatment of acute pharyngitis in adults
5. 慢性非アレルギー性鼻炎 chronic nonallergic rhinitis

Method development and validation of olprinone in human plasma by HPLC coupled with ESI-MS-MS: application to a pharmacokinetic study.

Wang H1, Zhang B, Sun X, Sun Y, Shi M.
Journal of chromatographic science.J Chromatogr Sci.2014 May-Jun;52(5):400-5. doi: 10.1093/chromsci/bmt049. Epub 2013 May 19.
A simple, specific and highly sensitive assay using liquid chromatography-tandem mass spectrometry with electrospray ionization was developed for the determination of olprinone in human plasma. Following the addition of codeine as an internal standard and simple liquid-liquid extraction with ethyl a
PMID 23690065

Neuroprotective effects of olprinone after cerebral ischemia/reperfusion injury in rats.

Genovese T1, Mazzon E, Paterniti I, Esposito E, Cuzzocrea S.
Neuroscience letters.Neurosci Lett.2011 Oct 3;503(2):93-9. doi: 10.1016/j.neulet.2011.08.015. Epub 2011 Aug 17.
Olprinone hydrochloride, a specific phosphodiesterase III inhibitor, has anti-inflammatory effects in addition to its inotropic and vasodilatory effects. The purpose of this study was to examine the beneficial effects of olprinone on cerebral ischemia reperfusion injury. In the present study, we exa
PMID 21872644

Olprinone, a PDE3 inhibitor, modulates the inflammation associated with myocardial ischemia-reperfusion injury in rats.

Di Paola R1, Mazzon E, Paterniti I, Impellizzeri D, Bramanti P, Cuzzocrea S.
European journal of pharmacology.Eur J Pharmacol.2011 Jan 15;650(2-3):612-20. doi: 10.1016/j.ejphar.2010.10.043. Epub 2010 Oct 27.
Coronary ischemia and subsequent reperfusion result in deleterious effects, one of the principal ones being vascular and myocardial inflammation. Olprinone hydrochloride, a specific phosphodiesterase III inhibitor, has anti-inflammatory effects in addition to its inotropic and vasodilator effects. T
PMID 21035441

〈Cases Reports〉The case of a newborn manifesting heart failure caused by a chorioangioma

Wada Norihisa,Inoue Tomohiro,Shinohara Toru,Takemura Tsukasa
ACTA MEDICA 38(2), 115-118, 2013-12
… An improvement of the mitral regurgitation 27 hours after birth resulted from olprinone hydrochloride administration, and mechanical ventilation was discontinued 2 days later. …
NAID 120005436006

Efficacy of Oral Sildenafil in a Beraprost-Treated Patient With Severe Pulmonary Hypertension Secondary to Type I Glycogen Storage Disease

UENO Michihiko,MURAKAMI Tomoaki,TAKEDA Atsuhito,KUBOTA Mitsuru
Circulation journal : official journal of the Japanese Circulation Society 73(10), 1965-1968, 2009-09-20
… The echocardiogram showed marked elevation of the right ventricular pressure and low cardiac output, and his symptoms deteriorated despite continuous infusion of olprinone hydrochloride. …
NAID 10025936602