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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/01/06 09:51:36」(JST)

English Journal

Retraction Note to: Different effects of olprinone on contractility in nonfatigued and fatigued diaphragm in dogs.

Fujii Y, Toyooka H.SourceCanadian Journal of Anesthesia, c/o Department of Anesthesia, The Ottawa Hospital - General Campus, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada, cja_office@cas.ca.
Canadian journal of anaesthesia = Journal canadien d'anesthesie.Can J Anaesth.2013 Apr 26. [Epub ahead of print]
PMID 23619612

Population pharmacokinetics of olprinone in patients undergoing cardiac surgery with cardiopulmonary bypass.

Tsubokawa T, Ishizuka S, Fukumoto K, Ueno K, Yamamoto K.SourceDepartment of Anesthesiology, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University Hospital, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan, tsune@med.kanazawa-u.ac.jp.
Journal of anesthesia.J Anesth.2013 Apr;27(2):243-50. doi: 10.1007/s00540-012-1505-4. Epub 2012 Oct 23.
PURPOSE: Olprinone, a phosphodiesterase type III inhibitor, is a strong inotrope and vasodilator that does not increase oxygen consumption and is often used during weaning from cardiopulmonary bypass (CPB). To control the pharmacological effects of olprinone, pharmacokinetic information is essential
PMID 23090059

The effect of olprinone compared with milrinone on diaphragmatic muscle function in dogs. Anesth Analg 1999;89:781-5. Retraction.

Fujii Y, Takahashi S, Toyooka H.
Anesthesia and analgesia.Anesth Analg.2013 Mar;116(3):745. doi: 10.1213/ANE.0b013e31828ac3d7.
PMID 23439829

Intermittent infusions of carperitide or inotoropes in out-patients with advanced heart failure.

Nishi Kiyoto,Sato Yukihito,Miyamoto Tadashi,Toma Masanao,Taniguchi Ryoji,Fukuhara Rei,Saijo Sayaka,Fujiwara Hisayoshi,Takatsu Yoshiki
Journal of cardiology 59(3), 366-373, 2012-05
… [Methods]: Between May 2005 and July 2009, we treated 11 patients presenting with advanced HF, who received a total of 369 infusions of carperitide, olprinone, dopamine, or dobutamine, once or twice weekly. … [Results]: Carperitide, olprinone, and catecholamines were administered to 8 (73 infusions of 0.030 ± 0.004 μg/kg/min for 3.3 ± 0.8 h), 4 (18 infusions of 0.070 ± 0.017 μg/kg/min for 3.3 ± 0.5 h), and 6 patients (278 infusions of 3.6 ± 1.9 μg/kg/min for 2.8 ± 1.0 h), respectively. …
NAID 120004108329

リンク元	「オルプリノン」
拡張検索	「olprinone hydrochloride」

Olprinone
Systematic (IUPAC) name
	5-imidazo[2,1-f]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile
Clinical data
Pregnancy cat.	?
Legal status	Rx-only. Not marketed in US and the EU
Routes	IV
Identifiers
CAS number	106730-54-5
ATC code	?
PubChem	CID 4593
UNII	4Y8BMI9YGC
Chemical data
Formula	C14H10N4O
Mol. mass	250.25 g/mol
	SMILES CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2;
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