WordNet

visible; "be sure of it; give me the ocular proof"- Shakespeare; "a visual presentation"; "a visual image" (同)visual
of or relating to or resembling the eye; "ocular muscles"; "an ocular organ"; "ocular diseases"; "the optic (or optical) axis of the eye"; "an ocular spot is a pigmented organ or part believed to be sensitive to light" (同)optic, optical, opthalmic
relating to or using sight; "ocular inspection"; "an optical illusion"; "visual powers"; "visual navigation" (同)optic, optical, visual

PrepTutorEJDIC

Ohio
《文》目の / 《まれ》視覚の,目で見た / (顕微鏡・望遠鏡などの)接眼レンズ,接眼鏡
高血圧[症] / 過度の緊張

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/10/03 21:36:48」(JST)

wiki en

Ocular hypertension is a clinical term describing the presence of elevated intraocular pressure in the absence of optic nerve damage or visual field loss.^[1]^[2]

For most individuals, the normal range of introcular pressure is between 10 mmHg and 21 mmHg.^[3]^[4] Elevated intraocular pressure is an important risk factor for glaucoma. The Ocular Hypertension Treatment Study, a large, multicentered, randomized clinical trial, determined that topical ocular hypotensive medication delays or prevents the onset of Primary Open-Angle Glaucoma.^[5] Accordingly, most individuals with consistently elevated intraocular pressures of greater than 21mmHg, particularly if they have other risk factors, are treated in an effort to prevent vision loss from glaucoma.

Pathophysiology

The pressure within the eye is maintained by the balance between the fluid that enters the eye through the ciliary body and the fluid that exits the eye through the trabecular meshwork.

Treatment

Ocular hypertension is treated with either medications or laser. Medications that lower intraocular pressure work by decreasing aqueous humor production and/or increasing aqueous humor outflow. Laser trabeculoplasty works by increasing outflow. The cannabinoids found in cannabis sativa and indica (marijuana) have been shown to reduce intraocular pressure, by up to 50% for approximately four to five hours. But due to the duration of effect, significant side-effect profile, and lack of research proving efficacy, the American Glaucoma Society issued a position statement in 2009 against the use of marijuana as a treatment for glaucoma. ^[6]

References

^ American Academy of Ophthalmology^{[dead link]}
^ American Optometric Association - Ocular Hypertension
^ webMD - Tonometry
^ eMedicine - Glaucoma Overview
^ Kass, M.A. (2002). "The Ocular Hypertension Treatment Study.". Arch Ophthalmol 120 (6): 701–713.
^ Jampel, H (2010). "American Glaucoma Society Position Statement: Marijuana and the treatment of glaucoma". J Glaucoma 19 (2): 75.

External links

eMedicine - Ocular Hypertension
National Eye Institute
International Glaucoma Association
Remedios Caseros Para La Presion Alta

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 高血圧の眼への影響 ocular effects of hypertension
2. 開放隅角緑内障：治療 open angle glaucoma treatment
3. 開放隅角緑内障：疫学、臨床症状、および診断 open angle glaucoma epidemiology clinical presentation and diagnosis
4. Portal hypertension in adults
5. 成人における門脈血栓症の疫学および病因 epidemiology and pathogenesis of portal vein thrombosis in adults

English Journal

Comparative Efficacy and Tolerability of Topical Prostaglandin Analogues for Primary Open-Angle Glaucoma and Ocular Hypertension.

Lin L1, Zhao YJ2, Chew PT3, Sng CC3, Wong HT4, Yip LW4, Wu TS5, Bautista D6, Teng M2, Khoo AL2, Lim BP2.
The Annals of pharmacotherapy.Ann Pharmacother.2014 Dec;48(12):1585-1593. Epub 2014 Sep 2.
OBJECTIVE: To systematically review the efficacy and tolerability of 4 prostaglandin analogues (PGAs) as first-line monotherapies for intraocular pressure (IOP) lowering in adult patients with primary open-angle glaucoma or ocular hypertension.DATA SOURCES: A literature search was performed in PubMe
PMID 25184309

Ripasudil: first global approval.

Garnock-Jones KP.
Drugs.Drugs.2014 Dec;74(18):2211-5. doi: 10.1007/s40265-014-0333-2.
Ripasudil hydrochloride hydrate (Glanatec® ophthalmic solution 0.4 %; hereafter referred to as ripasudil) is a small-molecule, Rho-associated kinase inhibitor developed by Kowa Company, Ltd. for the treatment of glaucoma and ocular hypertension. This compound, which was originally discovered by D.
PMID 25414122

Clinical profile of uveitis-related ocular hypertension.

Mahajan D1, Sharma R, Garg SP, Venkatesh P, Sihota R, Dada T.
International ophthalmology.Int Ophthalmol.2014 Dec;34(6):1221-6. doi: 10.1007/s10792-014-0008-8. Epub 2014 Oct 10.
The purpose of this article is to study the clinical and demographic profile of uveitis-related ocular hypertension (OHT) and evaluate risk factors predisposing to development of OHT in uveitis. Two hundred patients (200 eyes) with uveitis were evaluated for type of uveitis and the presence of OHT [
PMID 25301079

Japanese Journal

CLINICAL INVESTIGATION : Intraocular pressure decreases after muscle union surgery for highly myopic strabismus

Hayashi Shion,Sato Miho,Miura Hitomi [他]
Japanese journal of ophthalmology : the official international journal of the Japanese Ophthalmological Society 59(2), 118-123, 2015-03
NAID 40020401138

0.0015%タフルプロスト/0.5%チモロール配合点眼液(DE-111点眼液)の開放隅角緑内障および高眼圧症を対象としたオープンラベルによる長期投与試験

桑山泰明
あたらしい眼科 32(1), 133-143, 2015-01
NAID 40020345570

シリコーンオイル抜去後の高眼圧 (特集第67回日本臨床眼科学会講演集(6))

入谷麻世,野崎実穂,服部知明 [他]
臨床眼科 68(8), 1123-1126, 2014-08
NAID 40020161931

Related Pictures

★リンクテーブル★

リンク元	「眼圧亢進」「increased intraocular pressure」「elevated intraocular pressure」「高眼圧」「高眼圧症」
関連記事	「ocular」「hypertension」