WordNet

any of several substances found in the nuclei of all living cells; consists of a protein bound to a nucleic acid
of or relating to or constituting the nucleus of an atom; "nuclear physics"; "nuclear fission"; "nuclear forces"
(weapons) deriving destructive energy from the release of atomic energy; "nuclear war"; "nuclear weapons"; "atomic bombs" (同)atomic
constituting or like a nucleus; "annexation of the suburban fringe by the nuclear metropolis"; "the nuclear core of the congregation"
of or relating to or constituting the nucleus of a cell; "nuclear membrane"; "nuclear division"
any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/11/02 10:11:54」(JST)

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Renal PET-imaging with (11)C-metformin in a transgenic mouse model for chronic kidney disease.

Pedersen L1, Jensen JB1,2, Wogensen L1, Munk OL2, Jessen N1, Frøkiær J2, Jakobsen S3.
EJNMMI research.EJNMMI Res.2016 Dec;6(1):54. doi: 10.1186/s13550-016-0211-x. Epub 2016 Jun 23.
BACKGROUND: Organic cation transporters (OCTs) in the renal proximal tubule are important for the excretion of both exo- and endogenous compounds, and chronic kidney disease (CKD) alter the expression of OCT. Metformin is a well-known substrate for OCT, and recently, we demonstrated that positron em
PMID 27339044

Simultaneous determination of CRP and D-dimer in human blood plasma samples with White Light Reflectance Spectroscopy.

Koukouvinos G1, Petrou P2, Misiakos K3, Drygiannakis D4, Raptis I4, Stefanitsis G5, Martini S5, Nikita D5, Goustouridis D6, Moser I6, Jobst G7, Kakabakos S1.
Biosensors & bioelectronics.Biosens Bioelectron.2016 Oct 15;84:89-96. doi: 10.1016/j.bios.2015.11.094. Epub 2015 Dec 2.
A dual-analyte assay for the simultaneous determination of C-reactive protein (CRP) and D-dimer in human blood plasma based on a white light interference spectroscopy sensing platform is presented. Measurement is accomplished in real-time by scanning the sensing surface, on which distinct antibody a
PMID 26675113

Nrf2 as molecular target for polyphenols: A novel therapeutic strategy in diabetic retinopathy.

Nabavi SF1, Barber AJ2, Spagnuolo C3, Russo GL3, Daglia M4, Nabavi SM1, Sobarzo-Sánchez E5.
Critical reviews in clinical laboratory sciences.Crit Rev Clin Lab Sci.2016 Oct;53(5):293-312. doi: 10.3109/10408363.2015.1129530. Epub 2016 Feb 29.
Diabetic retinopathy is a microvascular complication of diabetes that is considered one of the leading causes of blindness among adults. More than 4.4 million people suffer from this disorder throughout the world. Growing evidence suggests that oxidative stress plays a crucial role in the pathophysi
PMID 26926494

Antiinflammatory Activities of Crebanine by Inhibition of NF-κB and AP-1 Activation through Suppressing MAPKs and Akt Signaling in LPS-Induced RAW 264.7 Macrophages

Down-regulation of mitogen-activated protein kinases and nuclear factor-κB signaling is involved in rapamycin suppression of TLR2-induced inflammatory response in monocytic THP-1 cells