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1. アンドロゲン不応症の発症機序と臨床的特徴pathogenesis and clinical features of disorders of androgen action [show details]
… X-linkage of the AR gene was established when the human cDNA was cloned from an X-chromosome library .… men with PAIS have normal sperm density . The external genitalia are those of a normal man, except that the penis may be small. The internal urogenital tract is normal.…
2. 環境中のアレルゲンサンプリングallergen sampling in the environment [show details]
… substance involves creating a complementary DNA (cDNA) library from the substance,… control and interlaboratory proficiency testing is voluntary. Only one large program, called the "Healthy Homes Project," has instituted a clinical laboratory proficiency testing program in which a common…
3. 遺伝学およびゲノミクスのためのツール：遺伝子発現プロファイリングtools for genetics and genomics gene expression profiling [show details]
… complementary DNAs (cDNAs) are synthesized by reverse transcription with an RNA-dependent DNA polymerase. This cDNA mixture is then combined with a… determine whether gene expression differences between healthy tissue and diseased tissue are due to changes in…
4. 学会が公開する診療ガイドラインのリンク：麻疹society guideline links measles [show details]
…Health England (PHE): National measles guidelines (2017) Communicable Diseases Network Australia (CDNA): National guidelines for public health units – Measles (2019) Australian Technical Advisory Group…
5. 学会が公開する診療ガイドラインのリンク：狂犬病society guideline links rabies [show details]
…Immunisation Handbook – Rabies and other lyssaviruses (2018) Communicable Diseases Network Australia (CDNA): National guidelines for public health units on rabies virus and other lyssavirus (including Australian…

English Journal

Targeting RyR2 with a phosphorylation site-specific nanobody reverses dysfunction of failing cardiomyocytes in rats.

Li T, Shen Y, Lin F, Fu W, Liu S, Wang C, Liang J, Fan X, Ye X, Tang Y, Ding M, Yang Y, Lei C, Hu S.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 Jun;33(6)7467-7478.
Chronic PKA phosphorylation of ryanodine receptor 2 (RyR2) has been shown to increase diastolic sarcoplasmic reticulum (SR) Ca leakage and lead to cardiac dysfunction. We hypothesize that intracellular gene delivery of an RyR2-targeting phosphorylation site-specific nanobody could preserve the contr
PMID 30885011

Novel binding partners for Prenylated Rab Acceptor 1 identified by a split-ubiquitin yeast two-hybrid screen.

Abu Irqeba A, Ogilvie JM.
BMC research notes. 2019 Mar;12(1)188.
Prenylated Rab Acceptor 1 (PRA1) is a transmembrane protein localized to the early secretory pathway. It has been found to interact with an array of Rab GTPases, leading to its hypothesized function in the recycling of Rab GTPases. However, all previous strategies used to screen for novel interactin
PMID 30925931

Characterization of the Rosa roxburghii Tratt transcriptome and analysis of MYB genes.

Huang X, Yan H, Zhai L, Yang Z, Yi Y.
PloS one. 2019 ;14(3)e0203014.
Rosa roxburghii Tratt (Rosaceae) has a fruit that is flavorful, economically valuable, and highly nutritious, providing numerous health benefits. Myeloblastosis (MYB) proteins play key roles in the development and fruit quality of R. roxburghii. However, there is little available genomic and transcr
PMID 30860996

Japanese Journal

Construction and Characterization of Normalized cDNA Libraries by 454 Pyrosequencing and Estimation of DNA Methylation Levels in Three Distantly Related Termite Species

Hayashi Yoshinobu,Shigenobu Shuji,Watanabe Dai,Toga Kouhei,Saiki Ryota,Shimada Keisuke,Bourguignon Thomas,Lo Nathan,Hojo Masaru,Maekawa Kiyoto,Miura Toru
PLoS ONE 8(9), e76678, 2013-09-30
… We generated normalized cDNA libraries from whole bodies, except for guts containing microbes, of almost all castes, sexes and developmental stages and sequenced them with the 454 GS FLX titanium system. … sjostedti library, while all except dnmt3 were found in R. …
NAID 120005347006

ブラシノステロイド情報伝達突然変異体bil2、bpgの機能解析

Bekh-Ochir Davaapurev,嶋田勢津子,中澤美紀,市川尚斉,松井南,中野明彦,浅見忠男,中野雄司
日本植物生理学会年会およびシンポジウム　講演要旨集 2011(0), 0862-0862, 2011
… また葉緑体制御に関わるブラシノステロイド情報伝達突然変異体の探索を目標として、Brz存在下においても緑化が促進されず低緑化を示す形質をbpg (Brz-insensitive pale green)変異としてアラビドプシス完全長cDNA高発現変異性であるFOXラインから新しいbpg変異体の探索を開始した。 …
NAID 130006998549

22. ブラシノステロイド情報伝達突然変異体のFOXラインからの探索と新しい変異体bil7の植物形態形成における機能解析(口頭発表,植物化学調節学会第46回大会)

宮地朋子,市川尚斉,松井南,中野明彦,浅見忠男,中野雄司
植物化学調節学会研究発表記録集 46(0), 38, 2011
… To identify new brassinosteroid signaling mutants, we used FOX (Full-length cDNA over-expressor gene) hunting system lines, which were overexpressed mutants of a normalized Arabidopsis full-length cDNA library. …
NAID 110008902431