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1. 乾癬の治療 treatment of psoriasis
2. 汗腺膿瘍（にきび）の治療 treatment of hidradenitis suppurativa acne inversa
3. 成人における再発寛解型多発性硬化症の治療 treatment of relapsing remitting multiple sclerosis in adults
4. リポイド類壊死症 necrobiosis lipoidica
5. 妊娠時の乾癬のマネージメント management of psoriasis in pregnancy

English Journal

Protective effects of nizofenone administration on the cognitive impairments induced by chronic restraint stress in mice.

Liu Y, Zhuang X, Gou L, Ling X, Tian X, Liu L, Zheng Y, Zhang L, Yin X.SourceDepartment of Pharmacology, School of Pharmacy, Xuzhou Medical College, Xuzhou 221004, China. Electronic address: cbpe200901@163.com.
Pharmacology, biochemistry, and behavior.Pharmacol Biochem Behav.2012 Sep 28;103(3):474-480. doi: 10.1016/j.pbb.2012.09.009. [Epub ahead of print]
The present study was aimed to investigate the effects of nizofenone administration on the chronic restraint stress-induced cognitive impairments in mice. Adult male mice were randomized into five groups: control group, nizofenone control group, chronic restraint stress group, and nizofenone treatme
PMID 23026061

Pharmacological evidence for a correlation between hippocampal CA1 cell damage and hyperlocomotion following global cerebral ischemia in gerbils.

Katsuta K, Umemura K, Ueyama N, Matsuoka N.SourceDepartment of Neuroscience, Medicinal Biology Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., 2-1-6 Kashima, Yodogawa, Osaka 532-8514, Japan.
European journal of pharmacology.Eur J Pharmacol.2003 Apr 25;467(1-3):103-9.
Global ischemia, induced in Mongolian gerbils by bilateral occlusion of the carotid arteries for 5 min, produced a significant increase in locomotor activity at 1 day post-occlusion and a severe loss of hippocampal CA1 neurons at 4 days post-occlusion. To explore the pharmacological relationship bet
PMID 12706462

Effect of ozagrel on locomotor and motor coordination after transient cerebral ischemia in experimental animal models.

Ichikawa K, Tazawa S, Hamano S, Kojima M, Hiraku S.SourcePharmacological Laboratories, Kissei Pharmaceutical Co., Ltd, Hotaka, Nagano, Japan. kiyoshi_ichikawa@pharm.kissei.co.jp
Pharmacology.Pharmacology.1999 Nov;59(5):257-65.
The effect of ozagrel, a selective thromboxane A(2) (TXA(2)) synthetase inhibitor, on the obstruction after cerebral ischemia-reperfusion was studied in experimental animal models. The reduced spontaneously locomotor activity and the obstruction of motor coordination were improved by the administrat
PMID 10529658

Therapy for Severe Subarachnoid Hemorrhage:-The Role of Continuous Monitoring of CBF, ICP and Measuring the Levels of Serum Complements (CH50, C3 and C4)-

河野輝昭,米川泰弘,三宅英則,後藤泰伸,半田寛,山下耕助,郭泰彦
Surgery for Cerebral Stroke 19(2), 173-177, 1991
… Twenty-one patients who were admitted to our department after the initial pilot study were divided into two groups: Group A, who received nizofenone fumarate (Econal) which is an antivasospasmotic agent, and Group B, who did not receive the drugs. …
NAID 130004668261