WordNet

a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs" (同)antibiotic drug
of or relating to antibiotic drugs

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抗生物質(ペニシリン,ストレプトマイシンなど) / 抗生[物質]の

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1. ペニシリン-アレルギー患者：セフェム系、カルバペネム系、およびモノバクタム系の使用 penicillin allergic patients use of cephalosporins carbapenems and monobactams
2. β-ラクタマーゼ阻害剤、カルバペネム系、およびモノバクタム系抗菌薬の併用 combination beta lactamase inhibitors carbapenems and monobactams
3. 基質特異性拡張型β-ラクタマーゼ extended spectrum beta lactamases
4. β-ラクタム系抗生物質：作用機序、耐性および有害作用 beta lactam antibiotics mechanisms of action and resistance and adverse effects
5. Principles of antimicrobial therapy of Pseudomonas aeruginosa infections

English Journal

Reclassification of the Specialized Metabolite Producer Pseudomonas mesoacidophila ATCC 31433 as a Member of the Burkholderia cepacia Complex.

Loveridge EJ1,2, Jones C3, Bull MJ3, Moody SC4, Kahl MW2, Khan Z2, Neilson L5,6, Tomeva M5,6, Adams SE2, Wood AC2, Rodriguez-Martin D2, Pinel I2, Parkhill J7, Mahenthiralingam E3, Crosby J8.
Journal of bacteriology.J Bacteriol.2017 Jun 13;199(13). pii: e00125-17. doi: 10.1128/JB.00125-17. Print 2017 Jul 1.
PMID 28439036

Prevalence and Antimicrobial Resistance of Salmonella enterica Serovar Indiana in China (1984-2016).

Gong J1,2, Kelly P3, Wang C2,4,5.
Zoonoses and public health.Zoonoses Public Health.2017 Jun;64(4):239-251. doi: 10.1111/zph.12328. Epub 2016 Dec 23.
PMID 28009105

A survey of inpatient practitioner knowledge of penicillin allergy at 2 community teaching hospitals.

Staicu ML1, Soni D2, Conn KM3, Ramsey A2.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.Ann Allergy Asthma Immunol.2017 May 20. pii: S1081-1206(17)30339-3. doi: 10.1016/j.anai.2017.04.023. [Epub ahead of print]
PMID 28539186

Japanese Journal

Origins of the β-lactam rings in natural products

TAHLAN Kapil,JENSEN Susan E
Journal of antibiotics
NAID 10031189619

Pseudomonas aeruginosaに対する各種抗菌薬の抗菌力の評価:特に新規に上梓されたprulifloxacin, pazufloxacinおよびbiapenemの評価

阿部教行,小松方,岩崎瑞穂,長坂陽子,福田砂織,松尾収二,島川宏一
The Japanese Journal of Antibiotics
Pseudomonas aeruginosaに対する新規に上梓されたprulifloxacin, pazufloxacinおよびbiapenemを含む計16薬剤の抗菌力を調査した。天理よろづ相談所病院で2003年4月から2004年3月の期間に分離されたP.aeruginosa 207株 (呼吸器系51%, 尿路系24%, …
NAID 130004396023

Aztreonam妊婦投与における臍帯組織内移行に関する検討

板倉敦夫,倉内修,水谷栄彦,友田豊,松澤克治
The Japanese Journal of Antibiotics
モノバクタム系抗生物質であるAztreonam (以下AZT) を子宮内感染妊婦に6時間毎に点滴静注投与を行い, 分娩時の母体血, 臍帯血, 膀帯組織内濃度を調べ, AZTの移行及び蓄積について検討した。さらに臍帯組織培養と組織学的検査を施行し, 臍帯炎に対する有用性を検討した。 母体血中濃度および臍帯血中濃度は数次投与によっても蓄積されず, 最終投与からの経過時間と相関がみられ …
NAID 130004395692

Related Links

Monobactam - an overview | ScienceDirect Topics

Monobactam is widely distributed in body tissues and fluids. It is regarded as a safe agent and has a similar toxicity profile to that of other β -lactam antibiotics. 15 Because there are no cross-hypersensitivity reactions with penicillin, these agents can be administered to patients who have a penicillin allergy.

Process Development for the Synthesis of a Monobactam ...

A scalable process for the novel monobactam antibiotic LYS228 has been developed. This paper covers a novel scalable process for producing β-lactam 10 in the multiple kilogram scale. An alternative approach to compound 7 without protecting-group exchange has been demonstrated to enable a shortened synthesis.

Monobactams - Creative Biolabs

At present, aztreonam is the unique commercially available monobactam antibiotic. Other types of monobactams include tigemonam, nocardicin A, and tabtoxin. Fig.1 Chemical structures of β-lactam antibiotics. Monobactams