微小管
English Journal
- Review: Structure and mechanism of the dynein motor ATPase.
- Schmidt H1, Carter AP1.
- Biopolymers.Biopolymers.2016 Aug;105(8):557-67. doi: 10.1002/bip.22856.
- Dyneins are multiprotein complexes that move cargo along microtubules in the minus end direction. The largest individual component of the dynein complex is the heavy chain. Its C-terminal 3500 amino-acid residues form the motor domain, which hydrolyses ATP in its ring of AAA+ (ATPases associated wit
- PMID 27062277
- Invited review: Microtubule severing enzymes couple atpase activity with tubulin GTPase spring loading.
- Bailey ME1, Jiang N2, Dima RI2, Ross JL3.
- Biopolymers.Biopolymers.2016 Aug;105(8):547-56. doi: 10.1002/bip.22842.
- Microtubules are amazing filaments made of GTPase enzymes that store energy used for their own self-destruction to cause a stochastically driven dynamics called dynamic instability. Dynamic instability can be reproduced in vitro with purified tubulin, but the dynamics do not mimic that observed in c
- PMID 27037673
- Development of novel cyclic peptides as pro-apoptotic agents.
- Brindisi M1, Maramai S1, Brogi S1, Fanigliulo E2, Butini S3, Guarino E1, Casagni A1, Lamponi S1, Bonechi C1, Nathwani SM4, Finetti F5, Ragonese F6, Arcidiacono P6, Campiglia P7, Valenti S1, Novellino E8, Spaccapelo R6, Morbidelli L5, Zisterer DM4, Williams CD4, Donati A1, Baldari C2, Campiani G9, Ulivieri C2, Gemma S1.
- European journal of medicinal chemistry.Eur J Med Chem.2016 Jul 19;117:301-20. doi: 10.1016/j.ejmech.2016.04.001. Epub 2016 Apr 5.
- Our recent finding that paclitaxel behaves as a peptidomimetic of the endogenous protein Nur77 inspired the design of two peptides (PEP1 and PEP2) reproducing the effects of paclitaxel on Bcl-2 and tubulin, proving the peptidomimetic nature of paclitaxel. Starting from these peptide-hits, we herein
- PMID 27150036
Japanese Journal
- 脳形成障害の分子診断 (特集 胎児脳形成障害の診断における最新の知見)
- 77 ヒト好酸球細胞内信号伝達におけるMicrotubulus Associated Protein (MAP) kinaseの活性化
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- 英
- microtubule
- ラ
- microtubulus
- 同
- 微細管、微細小管
- 関
- 細胞、チューブリン