WordNet

beta blocker (trade name Lopressor) used in treating hypertension and angina and arrhythmia and acute myocardial infarction; has adverse side effects (depression and exacerbation of congestive heart failure etc.) (同)Lopressor

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Preparation and evaluation of sustained-release matrix tablets based on metoprolol and an acrylic carrier using injection moulding.

Quinten T1, Andrews GP, De Beer T, Saerens L, Bouquet W, Jones DS, Hornsby P, Remon JP, Vervaet C.
AAPS PharmSciTech.AAPS PharmSciTech.2012 Dec;13(4):1197-211. doi: 10.1208/s12249-012-9848-6. Epub 2012 Sep 11.
Sustained-release matrix tablets based on Eudragit RL and RS were manufactured by injection moulding. The influence of process temperature; matrix composition; drug load, plasticizer level; and salt form of metoprolol: tartrate (MPT), fumarate (MPF) and succinate (MPS) on ease of processing and drug
PMID 22965662

Comparative effectiveness of beta-blockers in elderly patients with heart failure.

Kramer JM1, Curtis LH, Dupree CS, Pelter D, Hernandez A, Massing M, Anstrom KJ.
Archives of internal medicine.Arch Intern Med.2008 Dec 8;168(22):2422-8; discussion 2428-32. doi: 10.1001/archinternmed.2008.511.
BACKGROUND: Whether beta-blockers (BBs) other than carvedilol, metoprolol succinate, and bisoprolol fumarate (evidence-based beta-blockers [EBBBs]) improve survival in patients with heart failure (HF) is unknown. We compared the effectiveness of EBBBs vs non-EBBBs on survival.METHODS: Our study popu
PMID 19064824

Ding L1, Zhou X, Guo X, Song Q, He J, Xu G.
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2007 Jun 28;44(2):520-5. Epub 2007 Mar 4.
A sensitive liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) method has been developed and validated for the determination of bisoprolol in human plasma, using metoprolol as internal standard (I.S.). After alkalization with sodium hydroxide, the samples were extracted with
PMID 17418521