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1. コルチコトロピン-放出ホルモン（CRH）刺激試験corticotropin releasing hormone stimulation test [show details]
…and interpretation of the CRH stimulation test. Other tests used to determine the cause of Cushing syndrome are described separately. The corticotropin-releasing hormone (CRH) that controls corticotropin …
2. 成人における副腎不全の診断diagnosis of adrenal insufficiency in adults [show details]
… The stimulation with glucagon or growth hormone-releasing hexapeptide (GHRP-6) have been assessed but appear to have low sensitivity . None of these tests can be considered completely… follicle-stimulating hormone and luteinizing hormone and in possibly hypogonadal men by measuring serum testosterone and luteinizing hormone.…
3. Desmopressin (DDAVP) stimulation testdesmopressin ddavp stimulation test [show details]
… ACTH syndrome) The desmopressin test is used most commonly in countries where corticotropin-releasing hormone (CRH) is not available,… the availability of other tests), and desmopressin is the only peptide that is currently used. Desmopressin stimulation tests have been used to: Distinguish…
4. 子宮内膜症：長期GnRHアゴニスト療法endometriosis long term treatment with gonadotropin releasing hormone agonists [show details]
… binding to the GnRH receptor stimulates the pituitary to produce luteinizing hormone (LH) and follicle stimulating hormone (FSH).… administration of a gonadotropin-releasing hormone (GnRH) agonist is usually effective.… One potential benefit of these agents is avoiding the initial stimulation of pituitary gonadotropins seen with GnRH agonists.…
5. 成人における成長ホルモン欠乏症growth hormone deficiency in adults [show details]
… multiple deficiencies of other pituitary hormones correlated highly with a subnormal GH response to a stimulation test .… provocative test will confirm the diagnosis. For many years, the two standard tests have been insulin-induced hypoglycemia or the combination of arginine and GH-releasing hormone (GHRH).…

English Journal

Central Precocious Puberty as a Presenting Sign of Nonclassical Congenital Adrenal Hyperplasia: Clinical Characteristics.

Neeman B, Bello R, Lazar L, Phillip M, de Vries L.
The Journal of clinical endocrinology and metabolism. 2019 Jul;104(7)2695-2700.
Central precocious puberty (CPP) may be the first presentation of nonclassical congenital adrenal hyperplasia (NCCAH) in girls. Data on the prevalence and the clinical phenotype of CPP associated with NCCAH are sparse. To study the clinical and laboratory characteristics that could differentiate idi
PMID 30779848

Length of efficacy and effect of implant location in adult tom cats treated with a 9.4 mg deslorelin subcutaneous implant.

Romagnoli S, Baldan A, Ferro S, Righetti C, Scenna L, Gabai G, Badon T, Fontaine C, Mollo A, Stelletta C, Milani C.
Journal of feline medicine and surgery. 2019 Jun;21(6)507-519.
The objective of this study was to assess duration of efficacy, side effects and return to fertility following use of the 9.4 mg deslorelin implant (Suprelorin 12; Virbac) in cats, and test whether efficacy and duration of action are influenced by implantation site (interscapular vs periumbilical).
PMID 30056772

Personality and gonadal development as sources of individual variation in response to GnRH challenge in female great tits.

Caro SP, Cornil CA, van Oers K, Visser ME.
Proceedings. Biological sciences. 2019 May;286(1902)20190142.
Seasonal timing of reproduction is a key life-history trait, but we know little about the mechanisms underlying individual variation in female endocrine profiles associated with reproduction. In birds, 17β-oestradiol is a key reproductive hormone that links brain neuroendocrine mechanisms, involved
PMID 31039718

Japanese Journal

ざそう患者におけるＬＨ‐ＲＨ，ＴＲＨ負荷試験による視床下部‐下垂体機能の検討

相澤浩,新村眞人
皮膚 41(1), 5-8, 1999
… 26例と硬結嚢腫型の男性座瘡患者7例LH-RH (luteinizing hormone-releasing hormone), TRH (thyroid releasing hormone) 負荷試験を行し, 血中 luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin (PRL), thyroid stimulating hormone (TSH) の反応を健常群との比較について検 …
NAID 130004045955

インシュリン,TRH,LHRH三重負荷試験にて pituitary apoplexy が誘発された非機能性下垂体腺腫 : 症例報告と文献的考察

本道洋昭,河野充夫,小林勉,長谷川顕士,小倉憲一
脳神経外科ジャーナル 6(3), 194-199, 1997
患者は27歳,男性.インシュリン,TRH,LHRHの静脈内投与後3時間で頭痛が生じ,その後に視力・視野障害が急激に悪化した.頭部CTで腫瘍周囲および腫瘍内出血の所見を認めたため,下垂体卒中の診断で緊急にtranssphenoidal approachによる腫瘍摘出術を行った.内分泌負荷試験により誘発された下垂体卒中は非常に稀であり,自験例を含め23例が報告されているだけである.内分泌負荷試験による …
NAID 110003813018

思春期早発を伴った卵巣嚢腫の1例

黒部仁,山崎洋次,水野良児,吉田二教
日本小児外科学会雑誌 33(7), 1124-1128, 1997
症例は,2歳6ヵ月の女児.両側の乳腺の腫犬を主訴に来院した.血中ホルモン定量では LH , FSH の低値およびエストラジオール (E2) の高値を認めた. LH-RH 負荷試験で血中 LH, FSH ともに無反応を示した.頭部 MRI 検査にて異常を認めず,腹部超音波検査にて右卵巣に嚢胞性病変を認めた.以上の検査結果より2次性の思春期早発と診断し,右卵巣摘出術を施行した.病理組織検査では Cor …
NAID 110002085885