WordNet
- (botany) either of the two parts of a bilabiate corolla or calyx
- either the outer margin or the inner margin of the aperture of a gastropods shell
- either of two fleshy folds of tissue that surround the mouth and play a role in speaking
- an oily organic compound insoluble in water but soluble in organic solvents; essential structural component of living cells (along with proteins and carbohydrates) (同)lipide, lipoid
- the organic processes (in a cell or organism) that are necessary for life (同)metabolic_process
PrepTutorEJDIC
- 〈C〉『くちびる』,口もと / 《複数形で》(発音器官としての)くちびる,口 / 〈U〉《俗》生意気な言葉 / 〈C〉(容器などの)口,へり,縁;(峡谷・火山などの)口 / 〈C〉(植物の)唇弁(しんべん)
- 脂質,あぶら
- 新陳代謝,物質交代
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/04/08 05:29:17」(JST)
[Wiki en表示]
Lipid metabolism refers to the processes that involve the intercourse and degradation of lipids.
The types of lipids involved include:
- Bile salts
- Cholesterols
- Eicosanoids
- Glycolipids
- Ketone bodies
- Fatty acids - see also fatty acid metabolism
- Phospholipids
- Sphingolipids
- Steroid - see also steroidogenesis
- Triacylglycerols (fats) - see also lipolysis and lipogenesis
External links
- Lipid metabolism at the US National Library of Medicine Medical Subject Headings (MeSH)
- Ophardt, Charles E. (2003) Lipid Catabolism Summary. Virtual Chembook. Elmhurst College.
- King, Michael W. Fatty Acid, Omega-3 and Omega-6 Fatty Acid, Triglyceride, and Phospholipid Synthesis and Metabolism. The Medical Biochemistry Page.
- Breaking news and clinical trials about Lipid and Metabolism
Metabolism (Catabolism, Anabolism)
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General |
Metabolic pathway · Metabolic network
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Energy metabolism |
Aerobic Respiration
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Glycolysis → Pyruvate Decarboxylation → Citric Acid Cycle → Oxidative Phosphorylation (Electron Transport Chain + ATP synthase)
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Anaerobic Respiration
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Electron acceptors are other than oxygen
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Fermentation
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Glycolysis → Substrate-level phosphorylation (ABE, Ethanol, Lactic acid)
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Specific paths |
Protein metabolism
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Protein synthesis · Catabolism
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Carbohydrate metabolism
(Carbohydrate catabolism
and anabolism)
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Human
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Glycolysis ⇄ Gluconeogenesis
Glycogenolysis ⇄ Glycogenesis
Pentose phosphate pathway · Fructolysis · Galactolysis
Glycosylation (N-linked, O-linked)
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Nonhuman
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Photosynthesis (Carbon fixation)
Xylose metabolism
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Lipid metabolism
(Lipolysis, Lipogenesis)
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Fatty acid metabolism
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Fatty acid degradation (Beta oxidation) · Fatty acid synthesis
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Other
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Steroid metabolism · Sphingolipid metabolism · Eicosanoid metabolism · Ketosis
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Amino acid
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Amino acid synthesis · Urea Cycle
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Nucleotide metabolism
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Purine metabolism · Nucleotide salvage · Pyrimidine metabolism ·
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Other
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Metal metabolism (Iron metabolism) · Ethanol metabolism
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mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m
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k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon
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m (A16/C10), i (k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)
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- biochemical families: carbohydrates
- alcohols
- glycoproteins
- glycosides
- lipids
- eicosanoids
- fatty acids / intermediates
- phospholipids
- sphingolipids
- steroids
- nucleic acids
- constituents / intermediates
- proteins
- amino acids / intermediates
- tetrapyrroles / intermediates
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Metabolism: lipid metabolism / fatty acid metabolism, triglyceride and fatty acid enzymes
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Synthesis |
Malonyl-CoA synthesis
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- ATP citrate lyase
- Acetyl-CoA carboxylase
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Fatty acid synthesis/
Fatty acid synthase
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- Beta-ketoacyl-ACP synthase
- Β-Ketoacyl ACP reductase
- 3-Hydroxyacyl ACP dehydrase
- Enoyl ACP reductase
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Fatty acid desaturases
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- Stearoyl-CoA_desaturase-1
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Triacyl glycerol
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- Glycerol-3-phosphate dehydrogenase
- Thiokinase
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Degradation |
Acyl transport
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- Carnitine palmitoyltransferase I
- Carnitine-acylcarnitine translocase
- Carnitine palmitoyltransferase II
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Beta oxidation
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General
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- Acyl CoA dehydrogenase (ACADL
- ACADM
- ACADS
- ACADVL
- ACADSB)
- Enoyl-CoA hydratase
- Acetyl-CoA C-acyltransferase
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Unsaturated
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- Enoyl CoA isomerase
- 2,4 Dienoyl-CoA reductase
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Odd chain
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- Propionyl-CoA carboxylase
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Other
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- Hydroxyacyl-Coenzyme A dehydrogenase
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To acetyl-CoA
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- Malonyl-CoA decarboxylase
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Aldehydes
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- Long-chain-aldehyde dehydrogenase
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mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m
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k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon
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m (A16/C10), i (k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)
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Metabolism: lipid metabolism - eicosanoid metabolism enzymes
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Precursor |
- Phospholipase C
- Diacylglycerol lipase
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Prostanoids |
- PGE synthase
- Prostaglandin-E2 9-reductase
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Leukotrienes |
- 5-Lipoxygenase activating protein/Arachidonate 5-lipoxygenase
- LTA4 hydrolase (B4 synthesis)
- LTC4 synthase
- Gamma-glutamyl transpeptidase
- DPEP2
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Ungrouped |
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mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m
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k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon
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m (A16/C10), i (k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)
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Metabolism: lipid metabolism · glycolipid enzymes
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Sphingolipid |
To glycosphingolipid
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- Glycosyltransferase · Sulfotransferase
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To ceramide
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- From ganglioside: Beta-galactosidase
- Hexosaminidase A
- Neuraminidase
- Glucocerebrosidase
- From globoside: Hexosaminidase B
- Alpha-galactosidase
- Beta-galactosidase
- Glucocerebrosidase
- From sphingomyelin: Sphingomyelin phosphodiesterase (Sphingomyelin phosphodiesterase 1)
- From sulfatide: Arylsulfatase A
- Galactosylceramidase
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To sphingosine
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- Ceramidase
- ACER1
- ACER2
- ACER3
- ASAH1
- ASAH2
- ASAH2B
- ASAH2C
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Other
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Sphingosine kinase
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NCL |
- Palmitoyl protein thioesterase
- Tripeptidyl peptidase I
- CLN3
- CLN5
- CLN6
- CLN8
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Ceramide synthesis |
- Serine C-palmitoyltransferase (SPTLC1)
- Ceramide glucosyltransferase (UGCG)
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mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m
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k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon
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m (A16/C10), i (k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)
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Metabolism: lipid metabolism – ketones/cholesterol synthesis enzymes/steroid metabolism
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Mevalonate pathway |
To HMG-CoA |
- Acetyl-Coenzyme A acetyltransferase
- HMG-CoA synthase (regulated step)
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Ketogenesis |
- HMG-CoA lyase
- 3-hydroxybutyrate dehydrogenase
- Thiophorase
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To Mevalonic acid |
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To DMAPP |
- Mevalonate kinase
- Phosphomevalonate kinase
- Pyrophosphomevalonate decarboxylase
- Isopentenyl-diphosphate delta isomerase
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Geranyl- |
- Dimethylallyltranstransferase
- Geranyl pyrophosphate
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To cholesterol |
To lanosterol |
- Farnesyl-diphosphate farnesyltransferase
- Squalene monooxygenase
- Lanosterol synthase
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7-Dehydrocholesterol path |
- Lanosterol 14α-demethylase
- Sterol-C5-desaturase-like
- 7-Dehydrocholesterol reductase
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Desmosterol path |
- 24-dehydrocholesterol reductase
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To Bile acids |
- Cholesterol 7α-hydroxylase
- Sterol 27-hydroxylase
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Steroidogenesis |
To pregnenolone |
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To corticosteroids |
- aldosterone: 18-hydroxylase
- cortisol/cortisone: 17α-hydroxylase
- 11β dehydrogenase
- both: 3β dehydrogenase
- 21α-hydroxylase
- 11β-hydroxylase
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To sex hormones |
To androgens |
- 17α-hydroxylase/17,20 lyase
- 3β dehydrogenase
- 17β dehydrogenase
- 5α reductase
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To estrogens |
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Other/ungrouped |
- Steroid metabolism: sulfatase
- sulfotransferase
- Steroidogenic acute regulatory protein
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mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m
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k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon
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m (A16/C10), i (k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)
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noco (d)/cong/tumr, sysi/epon
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proc, drug (A10/H1/H2/H3/H5)
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UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Gene expression analysis supports tumor threshold over 2.0 cm for T-category breast cancer.
- Solvang HK1, Frigessi A2, Kaveh F3, Riis ML4, Lüders T4, Bukholm IR5, Kristensen VN6, Andreassen BK7.
- EURASIP journal on bioinformatics & systems biology.EURASIP J Bioinform Syst Biol.2016 Feb 8;2016(1):6. eCollection 2016.
- Tumor size, as indicated by the T-category, is known as a strong prognostic indicator for breast cancer. It is common practice to distinguish the T1 and T2 groups at a tumor size of 2.0 cm. We investigated the 2.0-cm rule from a new point of view. Here, we try to find the optimal threshold based on
- PMID 26900390
- The Effect of Copper And Zinc Nanoparticles on the Growth Parameters, Contents of Ascorbic Acid, and Qualitative Composition of Amino Acids and Acylcarnitines in Pistia stratiotes L. (Araceae).
- Olkhovych O1, Volkogon M2, Taran N1, Batsmanova L1, Kravchenko I1.
- Nanoscale research letters.Nanoscale Res Lett.2016 Dec;11(1):218. doi: 10.1186/s11671-016-1422-9. Epub 2016 Apr 23.
- The paper covers the research of copper and zinc nanoparticle effect on the content of ascorbic acid, and quantitative and qualitative composition of amino acids and acylcarnitines in Pistia stratiotes L. plants. Plant exposition to copper nanoparticles led to the decrease in (1) the amount of ascor
- PMID 27107771
- Proteomic and Glycomic Characterization of Rice Chalky Grains Produced Under Moderate and High-temperature Conditions in Field System.
- Kaneko K1, Sasaki M1, Kuribayashi N1, Suzuki H1, Sasuga Y2, Shiraya T2,3, Inomata T1, Itoh K1, Baslam M1, Mitsui T4,5.
- Rice (New York, N.Y.).Rice (N Y).2016 Dec;9(1):26. doi: 10.1186/s12284-016-0100-y. Epub 2016 May 31.
- BACKGROUND: Global climate models predict an increase in global mean temperature and a higher frequency of intense heat spikes during this century. Cereals such as rice (Oryza sativa L.) are more susceptible to heat stress, mainly during the gametogenesis and flowering stages. During periods of high
- PMID 27246013
Japanese Journal
- 糖・脂質代謝異常と認知症予防 (第5土曜特集 老化と老年疾患 : 研究・臨床の最前線) -- (認知症)
- Food Components Modulate Obesity and Energy Metabolism via the Transcriptional Regulation of Lipid-Sensing Nuclear Receptors (Nutrition and Food for Longevity : For the Well-Being of All : Proceedings of the 12th Asian Congress of Nutrition)
- GOTO Tsuyoshi,TAKAHASHI Nobuyuki,KAWADA Teruo
- Journal of nutritional science and vitaminology 61(Suppl.), S128-130, 2015-05
- NAID 40020444405
Related Links
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Related Pictures
★リンクテーブル★
[★]
- 英
- lipid metabolism, fat metabolism
- 関
- 脂質代謝
[★]
先天性脂質代謝異常、先天性脂質代謝異常症
[★]