levallorphan

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WordNet

  1. drug (trade name Lorfan) that is related to morphine but that counteracts the respiratory depression produced by morphine poisoning but without affecting its analgesic effects (同)Lorfan

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/04/11 20:54:40」(JST)

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English Journal

  • Microfabricated electrochemical detector for high-performance liquid chromatography.
  • Ogburn ET1, Dziewatkoski M, Moles D, Johnson JM, Heineman WR.
  • Analytical chemistry.Anal Chem.2011 Sep 15;83(18):6963-70. doi: 10.1021/ac200476j. Epub 2011 Aug 18.
  • A microfabricated electrochemical cell has been developed as a disposable detector for flow injection analysis (FIA) and high-performance liquid chromatography (HPLC). The simplicity of the fabrication process allows this detector to be used as a low-cost, disposable device that can be replaced easi
  • PMID 21598939
  • Inhibition of morphine-induced cAMP overshoot: a cell-based assay model in a high-throughput format.
  • Xia M1, Guo V, Huang R, Shahane SA, Austin CP, Nirenberg M, Sharma SK.
  • Cellular and molecular neurobiology.Cell Mol Neurobiol.2011 Aug;31(6):901-7. doi: 10.1007/s10571-011-9689-y. Epub 2011 May 20.
  • Opiates are not only potent analgesics but also drugs of abuse mainly because they produce euphoria. Chronic use of opiates results in the development of tolerance and dependence. Dr Marshall Nirenberg's group at the National Institutes of Health (NIH) was the first to use a cellular model system of
  • PMID 21598037
  • Exploration of catalytic properties of CYP2D6 and CYP3A4 through metabolic studies of levorphanol and levallorphan.
  • Bonn B1, Masimirembwa CM, Castagnoli N Jr.
  • Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2010 Jan;38(1):187-99. doi: 10.1124/dmd.109.028670.
  • CYP2D6 and CYP3A4, two members of the cytochrome P450 superfamily of monooxygenases, mediate the biotransformation of a variety of xenobiotics. The two enzymes differ in substrate specificity and size and characteristics of the active site cavity. The aim of this study was to determine whether the c
  • PMID 19797609

Japanese Journal

  • オピエートのフロンティア電子密度の統計解析
  • オピエート分子の構造に関する理論的研究
  • 情報化学討論会・構造活性相関シンポジウム講演要旨集 tokusi(0), JP31-JP31, 2001
  • NAID 130004575375
  • オピエート分子の構造に関する理論的研究

Related Links

Levallorphan (Lorfan, Naloxiphan) is a drug of the morphinan family which is used as an opioid antidote or antagonist. It acts as an antagonist on μ-opioid receptor and agonist on kappa receptors hence called partial agonist, and as a result, ...
13 Jun 2005 ... It should be used cautiously; levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory depression such as that induced by alcohol or other non-opioid central depressants.


Related Pictures

Pharma mcqs 2nd term test 2011OPIOID ANALGESICS Anton Kohút. - ppt video online downloadExploration of Catalytic Properties of CYP2D6 and CYP3A4 Through Metabolic Studies of OPIOID ANALGESICS Dr. Naila Abrar. - ppt video online downloadExploration of Catalytic Properties of CYP2D6 and CYP3A4 Through Metabolic Studies of بسم الله الرحمن الرحيم. - ppt downloadOPIOID ANALGESICS Dr. Hazar ppt downloadScreening methods for analgesics



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