白色瞳孔
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/28 02:33:48」(JST)
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| Leukocoria |
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A child with leukocoria due to retinoblastoma in the left eye
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| Classification and external resources |
| ICD-9-CM |
360.44 |
| DiseasesDB |
33379 |
| MedlinePlus |
003315 |
Leukocoria (also leukokoria[1] or white pupillary reflex) is an abnormal white reflection from the retina of the eye. Leukocoria resembles eyeshine, but leukocoria can occur in humans and other animals that lack eyeshine because their retina lacks a tapetum lucidum.
Leukocoria is a medical sign for a number of conditions, including Coats disease, congenital cataract, corneal scarring, melanoma of the ciliary body,[2] Norrie disease, ocular toxocariasis, persistence of the tunica vasculosa lentis (PFV/PHPV), retinoblastoma, and retrolental fibroplasia.
Because of the potentially life-threatening nature of retinoblastoma, a cancer, that condition is usually considered in the evaluation of leukocoria. In some rare cases (1%) the leukocoria is caused by Coats' disease (leaking retinal vessels).
Contents
- 1 Diagnosis
- 2 Media depictions
- 3 References
- 4 External links
Diagnosis
A fundus with retinoblastoma
On photographs taken using a flash, instead of the familiar red-eye effect leukocoria can cause a bright white reflection in an affected eye.[3] Leukocoria may appear also in low indirect light, similar to eyeshine.
Leukocoria can be detected by a routine eye exam (see Ophthalmoscopy). For screening purposes, the red reflex test is used. In this test, when a light is shone briefly through the pupil, an orange red reflection is normal. A white reflection is leukocoria.
Bryan Shaw helped develop a smart-phone app that can detect leukocoria in photos.[4]
Media depictions
- The fictional serial killer known as "The Collector", the main antagonist of the films The Collector (2009) and The Collection (2012), suffers the condition in both eyes.
- The fictional character from the "PonyLiving", Pudding Pop, suffers from the condition in both eyes. This has been elaborated on in episodes 15, 16, and 20.
References
- ^ thefreedictionary.com
- ^ Demirci H, Shields CL, Shields JA, Honavar SG, Eagle RC (January 2001). "Leucocoria as the presenting sign of a ciliary body melanoma in a child". The British Journal of Ophthalmology 85 (1): 115–6. PMC 1723667. PMID 11201946.
- ^ "The 'strange white light' that nearly killed baby Grace". Daily Mail. June 1, 2009.
- ^ National Public Radio, Morning Edition, October 31, 2014; http://www.npr.org/blogs/health/2014/10/31/359568507/look-here-phone-app-checks-photos-for-eye-disease
External links
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Wikimedia Commons has media related to Leukocoria. |
- PHPV Persistent Hyperplastic Primary Vitreous
- Retinoblastoma MedPix Images
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Eye: appearance phenomena
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| of the eye |
- Eyeshine
- Leukocoria
- Red-eye effect
- Red reflex
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| by the eye |
- Color appearance
- Abney effect
- Bezold–Brücke shift
- Chromatic adaptation
- Purkinje effect
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Index of the eye
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| Description |
- Anatomy
- Physiology
- Phenomena
- appearance
- visual
- optical illusions
- proteins
- Development
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| Disease |
- Congenital
- Corneal dystrophy
- Neoplasms and cancer
- Other
- Symptoms and signs
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| Treatment |
- Procedures
- Drugs
- infection
- glaucoma and miosis
- mydriatics
- vascular
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UpToDate Contents
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English Journal
- Two-Year-Old Boy With Leukocoria and Strabismus.
- Nguyen R1, Wilson MW2, Fernandez-Pineda I3, Brennan RC3, Furman WL3.
- Clinical pediatrics.Clin Pediatr (Phila).2016 Oct;55(12):1187-9. doi: 10.1177/0009922815614360. Epub 2015 Nov 3.
- PMID 26531178
- Prenatal Diagnosis of Persistent Hyperplastic Primary Vitreous: Report of 2 Cases and Review of the Literature.
- Esmer AC1, Sivrikoz TS2, Gulec EY3, Sezer S4, Kalelioglu I2, Has R2, Yuksel A2.
- Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.J Ultrasound Med.2016 Oct;35(10):2285-91. doi: 10.7863/ultra.15.11040. Epub 2016 Aug 31.
- Persistent hyperplastic primary vitreous is a spectrum of congenital ocular abnormalities characterized by leukocoria, microphthalmia, cataracts, extensive intravitreal hemorrhage, persistence of the hyaloid artery, glaucoma, and retinal detachment. It might be isolated or associated with congenital
- PMID 27582535
- Leukocoria and Decreased Vision Detected During a Routine Pediatric Screening Eye Examination.
- Ali MH1, Chau FY1, Abbasian J1.
- JAMA ophthalmology.JAMA Ophthalmol.2016 Sep 1;134(9):1069-70. doi: 10.1001/jamaophthalmol.2016.1687.
- PMID 27415836
Japanese Journal
- Clinical and Electron Microscopic Features of Retinoblastoma
- Karim Mohammed M.,Yamamoto Misao,Itoh Hiroshi
- The Kobe journal of the medical sciences 42(3), 163-172, 1996-06
- … A male child of 1-year, 6-month-old had a history of leukocoria of the left eye for approximately three months prior to admission into our facility. …
- NAID 110000018671
Related Links
- Leukocoria (also leukokoria or white pupillary reflex) is an abnormal white reflection from the retina of the eye. Leukocoria resembles eyeshine, but leukocoria can occur in humans and other animals that lack eyeshine because their retina ...
- What is leukocoria? Leukocoria literally means "white pupil." It occurs when the pupil (the round hole in the colored part of the eye) is white rather than the usual black [See figure 1]. How is leukocoria detected? In more obvious cases the ...
Related Pictures
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- 英
- leukocoria
- 関
- [[]]
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