isosthenuria

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/06/18 18:35:03」(JST)

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Isosthenuria refers to the excretion of urine whose specific gravity (concentration) is neither greater (more concentrated) nor less (more dilute) than that of protein-free plasma, typically 1.008-1.012. Isothenuria reflects renal tubular damage/failure of renal medullary function.

A closely related term is hyposthenuria, where the urine has a relatively low specific gravity, though not necessarily equal to that of plasma. Therefore, unlike isosthenuria, this condition is not associated with renal failure as the kidney tubules have altered the glomerular filtrate

Clinical significance

This is the hallmark of such disease states as chronic and acute renal failure in which the kidneys lack the ability to concentrate or dilute the urine and so the initial filtrate of the blood remains unchanged despite the need to conserve or excrete water based on the body's hydration status.

Sickle-cell trait, the heterozygous form of sickle-cell disease, presents with a normal hematological picture but is associated with isosthenuria

See also

• hypersthenuria

References

UpToDate Contents

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• 1. ファブリー病の臨床的特徴および診断 clinical features and diagnosis of fabry disease

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• Fabry's disease: an example of cardiorenal syndrome type 5.

• Sharma A1, Sartori M, Zaragoza JJ, Villa G, Lu R, Faggiana E, Brocca A, Di Lullo L, Feriozzi S, Ronco C.
• Heart failure reviews.Heart Fail Rev.2015 Aug 1. [Epub ahead of print]
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• PMID 26232292

• A retrospective study of end-stage renal disease in captive polar bears (Ursus maritimus).

• LaDouceur EE, Davis B, Tseng F.
• Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.J Zoo Wildl Med.2014 Mar;45(1):69-77.
• This retrospective study summarizes 11 cases of end-stage renal disease (ESRD) in captive polar bears (Ursus maritimus) from eight zoologic institutions across the United States and Canada. Ten bears were female, one was male, and the mean age at the time of death was 24 yr old. The most common clin
• PMID 24712164

• Amyloid A amyloidosis with subcutaneous drug abuse.

• Mendoza JM1, Peev V1, Ponce MA2, Thomas DB3, Nayer A1.
• Journal of renal injury prevention.J Renal Inj Prev.2013 Nov 2;3(1):11-6. doi: 10.12861/jrip.2014.06. eCollection 2014.
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• PMID 25340157

Japanese Journal

• Fanconi症候群を合併したSjögren症候群の1例

• 奈良医学雑誌 45(1), 44-50, 1994-02-28
• NAID 120004973628

• 腎疾患,高血圧症の電解質(Na,Cl)クリアランスに関する臨床的研究 : 水利尿,滲透圧性利尿に関連して

• 千葉医学会雑誌 35(5), 2140-2163, 1960-01
• NAID 110007346053

Related Links

• Isosthenuria | definition of isosthenuria by Medical dictionary

isosthenuria [i″sos-thĕ-nu´re-ah] excretion of urine that has not been concentrated by the kidneys and has the same osmolality as that of plasma. i·sos·the·nu·ri·a (ī-sos'thē-nyū'rē-ă, ī'sō-sthē-), A state in chronic renal disease in which ...

• Isosthenuria | Define Isosthenuria at Dictionary.com

isosthenuria i·sos·the·nu·ri·a (ī-sŏs'thə-nur'ē-ə, ī'sō-sthě-) n. A condition in chronic renal disease in which the kidneys cannot form urine with a higher or a lower specific gravity than that of protein-free plasma.

Related Pictures

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★リンクテーブル★

リンク元

「等張尿」

「等張尿」

　　[★]

英

isosthenuria

関

低張尿、高張尿、尿

• 血漿浸透圧と等張の尿
• 尿比重：1.010-1.012
• 尿浸透圧：285-290 mOsm/kg