interleukin-1 receptor accessory protein

• インターロイキン1受容体アクセサリータンパク質

WordNet

1. clothing that is worn or carried, but not part of your main clothing (同)accoutrement, accouterment
2. a supplementary component that improves capability (同)appurtenance, supplement, add-on
3. furnishing added support; "an ancillary pump"; "an adjuvant discipline to forms of mysticism"; "The mind and emotions are auxiliary to each other" (同)adjunct, ancillary, adjuvant, appurtenant, auxiliary
4. someone who helps another person commit a crime (同)accessary
5. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
6. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
7. any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system

PrepTutorEJDIC

1. =accessory
2. 《通例複数形で》(…への)『付属品』,アクセサリー《+『for』+『名』》 / (法律用語で)従犯者,犯人隠匿(いんとく)者 / 付属の / 従犯の
3. 蛋白(たんばく)質
4. =sense organ / 受信装置

UpToDate Contents

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• 1. 周期性発熱症候群およびその他の自己炎症性疾患：概要 periodic fever syndromes and other autoinflammatory diseases an overview
• 2. 複合免疫不全 combined immunodeficiencies
• 3. クリオピリン関連周期性発熱症候群および関連疾患 cryopyrin associated periodic syndromes and related disorders
• 4. リウマチ性疾患におけるサイトカインネットワーク：治療の意味 cytokine networks in rheumatic diseases implications for therapy
• 5. 免疫系におけるサイトカインの役割 role of cytokines in the immune system

English Journal

• Inhibition of IL-1 Signaling by Antisense Oligonucleotide-mediated Exon Skipping of IL-1 Receptor Accessory Protein (IL-1RAcP).

• Yılmaz-Eliş AS, Aartsma-Rus A, 't Hoen PA, Safdar H, Breukel C, van Vlijmen BJ, van Deutekom J, de Kimpe S, van Ommen GJ, Verbeek JS.SourceCenter for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.
• Molecular therapy. Nucleic acids.Mol Ther Nucleic Acids.2013 Jan 22;2:e66. doi: 10.1038/mtna.2012.58.
• The cytokine interleukin 1(IL-1) initiates a wide range of proinflammatory cascades and its inhibition has been shown to decrease inflammation in a variety of diseases. IL-1 receptor accessory protein (IL-1RAcP) is an indispensible part of the IL-1R complex that stabilizes IL-1/IL-1R interaction and
• PMID 23340324

• One target-two different binding modes: structural insights into gevokizumab and canakinumab interactions to interleukin-1β.

• Blech M, Peter D, Fischer P, Bauer MM, Hafner M, Zeeb M, Nar H.SourceDepartment of Lead Identification and Optimization Support, Structural Research Group, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397 Biberach, Germany. michaela.blech@boehringer-ingelheim.com
• Journal of molecular biology.J Mol Biol.2013 Jan 9;425(1):94-111. doi: 10.1016/j.jmb.2012.09.021. Epub 2012 Oct 3.
• Interleukin-1β (IL-1β) is a key orchestrator in inflammatory and several immune responses. IL-1β exerts its effects through interleukin-1 receptor type I (IL-1RI) and interleukin-1 receptor accessory protein (IL-1RAcP), which together form a heterotrimeric signaling-competent complex. Canakinumab
• PMID 23041424

Japanese Journal

• 神経細胞間シナプス形成とその調節メカニズム

• 日本結晶学会誌 57(5), 304-309, 2015
• NAID 130005105679

• IL1RAPL1欠損マウスの表現型解析

• 日本薬理学雑誌 145(4), 187-192, 2015
• NAID 130005061554

• An emerging phenotype of Xq22 microdeletions in females with severe intellectual disability, hypotonia and behavioral abnormalities

• Journal of human genetics 59(6), 300-306, 2014-06
• NAID 40020109284

Related Links

• IL1RAP - Interleukin-1 receptor accessory protein precursor ...

The interleukin-36 receptor complex is a heterodimer of IL1RL2 and IL1RAP; the association is inhibited by IL36RN (By similarity). The interleukin-1 receptor complex is a heterodimer of IL1R1 and IL1RAP. Associates with IL1R2 to ...

• Interleukin-1 Receptor Accessory Protein: Interleukin 1 ...

Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene ...

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★リンクテーブル★

リンク元	「インターロイキン1受容体アクセサリータンパク質」
関連記事	「accessory」「interleukin」「accessory protein」「interleukins」

「インターロイキン1受容体アクセサリータンパク質」

　　[★]

英

interleukin-1 receptor accessory protein

「accessory」

　　[★]

• adj.

• 付属の、アクセサリーの、副

• n.

• 付属物

関

adjunct、adjunctive、appendage

　 　 　 　 　 　

「interleukin」

　　[★] インターロイキン IL 　

「accessory protein」

　　[★]

• アクセサリータンパク質

「interleukins」

　　[★] インターロイキン IL