抑制性Smadタンパク質
WordNet
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- a substance that retards or stops an activity
- restrictive of action; "a repressive regime"; "an overly strict and inhibiting discipline" (同)repressive, repressing
PrepTutorEJDIC
- 蛋白(たんばく)質
- 抑制する人(物) / 化学反応抑制剤
- samariumの化学記号
UpToDate Contents
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- 1. プロテインC欠乏症protein c deficiency [show details]
…generation and factor X activation . The inhibitory effect of aPC is enhanced by protein S, another vitamin K-dependent anticoagulant protein. Inherited deficiency of protein C can lead to thrombophilia (increased …
- 2. 鉄のバランス調節regulation of iron balance [show details]
… Signal transduction of BMPs occurs through SMAD proteins; conditional inactivation of Smad4 in mouse liver… attenuating the SMAD signaling . However, full hepcidin inhibition by ERFE requires an attenuated BMP pathway, strengthening the complex process of hepcidin inhibitory control .…
- 3. 全身性硬化症(強皮症)の病因pathogenesis of systemic sclerosis scleroderma [show details]
… A central role for the Smad family of proteins is postulated. Smads are evolutionarily conserved proteins that mediate transcriptional activation… reduction in inhibitory signals. Positive paracrine mediators may be derived from immune cells, from endothelial cells, or from the fibroblasts themselves. In turn, inhibitory influences…
- 4. プロテインS欠乏症protein s deficiency [show details]
… cofactor for activated protein C, which inactivates procoagulant factors Va and VIIIa, reducing thrombin generation . Protein S also serves as a cofactor for activated protein C in enhancing fibrinolysis …
- 5. 維持透析患者における蛋白質摂取protein intake in maintenance hemodialysis patients [show details]
… to monitor protein intake, along with other measures of nutrition among these patients. It is difficult to directly measure protein intake. A method that is commonly used to estimate protein intake is to …
English Journal
- Oridonin Inhibits Myofibroblast Differentiation and Bleomycin-induced Pulmonary Fibrosis by Regulating Transforming Growth Factor β (TGFβ)/Smad Pathway.
- Fu Y1,2, Zhao P2,3, Xie Z1,2, Wang L1, Chen S1,2.
- Medical science monitor : international medical journal of experimental and clinical research.Med Sci Monit.2018 Oct 22;24:7548-7555. doi: 10.12659/MSM.912740.
- PMID 30347408
- Progesterone Antagonizes Dexamethasone-Regulated Surfactant Proteins In Vitro.
- Kunzmann S1,2, Ottensmeier B2, Speer CP2, Fehrholz M2.
- Reproductive sciences (Thousand Oaks, Calif.).Reprod Sci.2018 Oct 15:1933719118804668. doi: 10.1177/1933719118804668. [Epub ahead of print]
- PMID 30317939
- CtBP represses Dpp-dependent Mad activation during Drosophila eye development.
- Eusebio N1, Tavares L1, Pereira PS2.
- Developmental biology.Dev Biol.2018 Oct 1;442(1):188-198. doi: 10.1016/j.ydbio.2018.07.018. Epub 2018 Jul 19.
- PMID 30031756
Japanese Journal
- The Comparison between Single vs Repeated Administration of Wnt3A of HPDL Cells
- TMEPAI/PMEPA1 enhances tumorigenic activities in lung cancer cells
- Mutual interaction of kisspeptin, estrogen and bone morphogenetic protein-4 activity in GnRH regulation by GT1-7 cells
Related Links
- 1. EMBO J. 2001 Aug 1;20(15):4132-42. Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads. Itoh F(1), Asao H, Sugamura K, Heldin CH, ten Dijke P, Itoh S. Author ...
- Inhibitory Smads, i.e. Smad6 and Smad7, are potent antagonists of the BMP–Smad pathway by interacting with activated bone morphogenetic protein (BMP) type I receptors and thereby preventing the activation of ...
★リンクテーブル★
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- 英
- inhibitory Smad protein
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- 関
- blocker、depressant、suppressant
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- 関
- inhibiting、suppressive
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サマリウム
- 関
- samarium