職業性膀胱癌
WordNet
- suitable to stand up to hard wear; "industrial carpeting"
- employed in industry; "the industrial classes"; "industrial work"
- having highly developed industries; "the industrial revolution"; "an industrial nation"
- of or relating to or resulting from industry; "industrial output"
- type genus of the family Cancridae (同)genus Cancer
- the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 (同)Cancer the Crab, Crab
- (astrology) a person who is born while the sun is in Cancer (同)Crab
- a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
- any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream (同)malignant neoplastic disease
- a bag that fills with air
- a distensible membranous sac (usually containing liquid or gas) (同)vesica
PrepTutorEJDIC
- 『産業』(『工業』)『の』,産業(工業)による / 高度に発達した産業(工業)を持つ / 産業(工業)用の
- 〈U〉〈C〉『がん』 / 〈U〉〈C〉害悪 / 《Cancer》(星座の)カニ座
- (人間・動物の)襄(のう),ぼうこう,(魚の)浮き袋;気胞 嚢に似た物
UpToDate Contents
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English Journal
- Biophysical characterization of bladder cancer cells with different metastatic potential.
- Liu H1, Tan Q, Geddie WR, Jewett MA, Phillips N, Ke D, Simmons CA, Sun Y.Author information 1Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, ON, M5S 3G8, Canada.AbstractSpecific membrane capacitance (SMC) and Young's modulus are two important parameters characterizing the biophysical properties of a cell. In this work, the SMC and Young's modulus of two cell lines, RT4 and T24, corresponding to well differentiated (low grade) and poorly differentiated (high grade) urothelial cell carcinoma (UCC), respectively, were quantified using microfluidic and AFM measurements. Quantitative differences in SMC and Young's modulus values of the high-grade and low-grade UCC cells are, for the first time, reported.
- Cell biochemistry and biophysics.Cell Biochem Biophys.2014 Mar;68(2):241-6. doi: 10.1007/s12013-013-9702-9.
- Specific membrane capacitance (SMC) and Young's modulus are two important parameters characterizing the biophysical properties of a cell. In this work, the SMC and Young's modulus of two cell lines, RT4 and T24, corresponding to well differentiated (low grade) and poorly differentiated (high grade)
- PMID 23793959
- Sulforaphane induces reactive oxygen species-mediated mitotic arrest and subsequent apoptosis in human bladder cancer 5637 cells.
- Park HS1, Han MH2, Kim GY3, Moon SK4, Kim WJ5, Hwang HJ6, Park KY7, Choi YH8.Author information 1School of Korean Medicine, Pusan National University, Yangsan 626-870, Republic of Korea.2Anti-Aging Research Center & Blue-Bio Industry Regional Innovation Center, Dongeui University, Busan 614-714, Republic of Korea.3Laboratory of Immunobiology, Department of Marine Life Sciences, Jeju National University, Jeju 690-756, Republic of Korea.4School of Food Science and Technology, Chung-Ang University, Ansung 456-756, Republic of Korea.5Department of Urology, Chungbuk National University College of Medicine, Cheongju 361-763, Republic of Korea.6Anti-Aging Research Center & Blue-Bio Industry Regional Innovation Center, Dongeui University, Busan 614-714, Republic of Korea; Department of Food and Nutrition, College of Human Ecology, Dongeui University, Busan 614-714, Republic of Korea.7Department of Food and Nutrition, Pusan National University, Busan 609-735, Republic of Korea.8Anti-Aging Research Center & Blue-Bio Industry Regional Innovation Center, Dongeui University, Busan 614-714, Republic of Korea; Department of Biochemistry, Dongeui University College of Oriental Medicine, Busan 614-052, Republic of Korea. Electronic address: choiyh@deu.ac.kr.AbstractThe present study was undertaken to determine whether sulforaphane-derived reactive oxygen species (ROS) might cause growth arrest and apoptosis in human bladder cancer 5637 cells. Our results show that the reduced viability of 5637 cells by sulforaphane is due to mitotic arrest, but not the G2 phase. The sulforaphane-induced mitotic arrest correlated with an induction of cyclin B1 and phosphorylation of Cdk1, as well as a concomitant increased complex between cyclin B1 and Cdk1. Sulforaphane-induced apoptosis was associated with the activation of caspase-8 and -9, the initiators caspases of the extrinsic and intrinsic apoptotic pathways, respectively, and activation of effector caspase-3 and cleavage of poly (ADP-ribose) polymerase. However, blockage of caspase activation inhibited apoptosis and abrogated growth inhibition in sulforaphane-treated 5637 cells. This study further investigated the roles of ROS with respect to mitotic arrest and the apoptotic effect of sulforaphane, and the maximum level of ROS accumulation was observed 3h after sulforaphane treatment. However, a ROS scavenger, N-acetyl-L-cysteine, notably attenuated sulforaphane-mediated apoptosis as well as mitotic arrest. Overall, these results suggest that sulforaphane induces mitotic arrest and apoptosis of 5637 cells via a ROS-dependent pathway.
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.Food Chem Toxicol.2014 Feb;64:157-65. doi: 10.1016/j.fct.2013.11.034. Epub 2013 Dec 1.
- The present study was undertaken to determine whether sulforaphane-derived reactive oxygen species (ROS) might cause growth arrest and apoptosis in human bladder cancer 5637 cells. Our results show that the reduced viability of 5637 cells by sulforaphane is due to mitotic arrest, but not the G2 phas
- PMID 24296129
- Cancer incidence among workers occupationally exposed to dinitrotoluene in the copper mining industry.
- Seidler A1, Brüning T, Taeger D, Möhner M, Gawrych K, Bergmann A, Haerting J, Bolt HM, Straif K, Harth V.Author information 1Faculty of Medicine Carl Gustav Carus, Institute and Policlinic of Occupational and Social Medicine, TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany, andreas.seidler@mailbox.tu-dresden.de.AbstractPURPOSE: Epidemiological and toxicological studies point to a potential carcinogenic effect of dinitrotoluene (DNT), particularly with respect to renal and urothelial cancer.
- International archives of occupational and environmental health.Int Arch Occup Environ Health.2014 Feb;87(2):117-24. doi: 10.1007/s00420-012-0842-9. Epub 2012 Dec 30.
- PURPOSE: Epidemiological and toxicological studies point to a potential carcinogenic effect of dinitrotoluene (DNT), particularly with respect to renal and urothelial cancer.METHODS: The cohort comprised all men born between 1920 and 1974 (n = 16,441) who were gainfully employed between 1953 and 199
- PMID 23274286
Japanese Journal
- Detection of tumor-associated antigens in culture supernatants using autoantibodiesin sera from patients with bladder cancer
- A numerical study of a mathematical model of pulsed immunotherapy for superficial bladder cancer
- Increased Mortality Risk for Cancers of the Kidney and Other Urinary Organs among Chinese Herbalists
Related Links
- Glashan RW. Industrial bladder cancer. Br Med J (Clin Res Ed) 1982 Feb 27; 284 (6316):614–615. [PMC free article] [] Vineis P, Pastore G, Aimone G, Costa G, Masiero C. Incidenza ed età di insorgenza dei tumori ...
- A risk factor is anything that changes your chance of getting a disease such as cancer. Different cancers have different risk factors. Some risk factors, like smoking, can be changed. Others, like a person’s age or family ...
★リンクテーブル★
[★]
- 英
- industrial bladder cancer, occupational bladder cancer
- 関
- 膀胱腫瘍
[★]
- 関
- industry
[★]
膀胱 urinary bladder
胆嚢 gallbladder
[★]
- 同
- 癌腫
- 関
- tumor