human monocytotropic ehrlichiosis

WordNet

1. sing with closed lips; "She hummed a melody"
2. a humming noise; "the hum of distant traffic" (同)humming
3. be noisy with activity; "This office is buzzing with activity" (同)buzz, seethe
4. sound with a monotonous hum (同)thrum
5. make a low continuous sound; "The refrigerator is humming"
6. relating to a person; "the experiment was conducted on 6 monkeys and 2 human subjects"
7. characteristic of humanity; "human nature"
8. having human form or attributes as opposed to those of animals or divine beings; "human beings"; "the human body"; "human kindness"; "human frailty"

PrepTutorEJDIC

1. 〈ハチ・機械などが〉『ブンブンいう』,ブーンと鳴る / 『鼻歌を歌う』,ハミングスル / (ちゅうちょ・当惑で)ふむふむいう / 《話》〈雰囲気・事業などが〉活気がある,活発に動く;(…で)活気づく《+『with』+『名』》 / …‘を'『ハミングで歌う』,鼻歌を歌って…‘を'(ある状熊に)する / (ハチ・機械などの)『ブンブン』[『うなる音』];鼻歌 / (雑踏などの)ガヤガヤ]いう音],騒音 / ふ‐む,う‐ん(ちゅうちょ・当惑・黙考・疑惑・不快などの声)
2. (動物・神に対して)『人間の』,人の / 『人間らいし』,人間的な,人情味のある / 〈C〉《複数形》(動物に怠して)人間(human being) / 〈U〉《the human》人類

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/02/18 21:57:11」(JST)

wiki en

[Wiki en表示]

Human monocytic ehrlichiosis
Ehrlichia chaffeensis
Classification and external resources
ICD-9	082.41
DiseasesDB	31131
MedlinePlus	001381
eMedicine	med/3391
MeSH	D016873

Human monocytotropic ehrlichiosis (HME) is a form of ehrlichiosis associated with Ehrlichia chaffeensis.

This bacteria is an obligate intracellular pathogen affecting monocytes and macrophages.

Ecology & Epidemiology

In the USA, HME occurs across the south-central, southeastern, and mid-Atlantic states, regions where both the white-tailed deer (Odocoileus virginianus) and lone star ticks (Amblyomma americanum) thrive.

HME occurs in California in Ixodes pacificus ticks and in Dermacentor variabilis ticks.

Nearly 600 cases were reported to the CDC in 2006. In 2001–2002, the incidence was highest in Missouri, Tennessee, and Oklahoma, as well as in people older than 60.

Symptoms

The most common symptoms are fever, headache, malaise, and muscle aches (myalgia). Compared to human granulocytic ehrlichiosis, rash is more common. Laboratory abnormalities include thrombocytopenia, leukopenia, and elevated liver tests.

The severity of the illness can range from minor or asymptomatic to life-threatening. CNS involvement may occur. A serious septic or toxic shock-like picture can also develop, especially in patients with impaired immunity.

Diagnosis

Tick exposure is often overlooked. For patients living in high-prevalence areas who spend time outdoors, a high degree of clinical suspicion should be employed.

Ehrlichia serologies can be negative in the acute period. PCR is therefore the laboratory diagnostic tool of choice.

Treatment

If Ehrlichiosis is suspected, treatment should not be delayed while waiting for a definitive laboratory confirmation, as prompt doxycycline therapy has been associated with improved outcomes. Doxycycline is the treatment of choice.

Presentation during early pregnancy can complicate treatment.

Rifampin has been used in pregnancy and in patients allergic to doxycycline.

References

See also

• monocyte
• Human granulocytic anaplasmosis
• Human ewingii ehrlichiosis

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. ヒトエーリキア症およびアナプラズマ症 human ehrlichiosis and anaplasmosis
• 2. エーリキアの生物学 biology of ehrlichiae
• 3. 小児の急性ウイルス性脳炎：治療と予防 acute viral encephalitis in children treatment and prevention
• 4. 犬からの人畜共通感染症 zoonoses from dogs
• 5. 猫からの人畜共通感染症 zoonoses from cats

English Journal

• The role of CD8 T lymphocytes in rickettsial infections.

• Walker DH1, Dumler JS.
• Seminars in immunopathology.Semin Immunopathol.2015 May;37(3):289-99. doi: 10.1007/s00281-015-0480-x. Epub 2015 Apr 1.
• Arthropod-borne obligately intracellular bacteria pose a difficult challenge to the immune system. The genera Rickettsia, Orientia, Ehrlichia, and Anaplasma evolved mechanisms of immune evasion, and each interacts differently with the immune system. The roles of CD8 T cells include protective immuni
• PMID 25823954

• A Tick Vector Transmission Model of Monocytotropic Ehrlichiosis.

• Saito TB1, Walker DH1.
• The Journal of infectious diseases.J Infect Dis.2015 Mar 3. pii: jiv134. [Epub ahead of print]
• BACKGROUND:  Ehrlichioses are emerging, tick-borne diseases distributed worldwide. Previously established animal models use needle inoculation as a mode of infection; however, there is limited representation of natural transmission in artificially inoculated models compared with transmission by th
• PMID 25737562

Related Links

• Human monocytotropic ehrlichiosis | definition of human ...

human monocytotropic ehrlichiosis (HME), an acute infectious disease characterized by fever, chills, headache, muscle and joint pain, and variable respiratory, gastrointestinal, and systemic involvement; hematologic ...

• Human monocytotropic ehrlichiosisとは - goo Wikipedia ...

Human monocytotropic ehrlichiosis [1] (HME) is a form of ehrlichiosis associated with Ehrlichia chaffeensis. [2] This bacteria is an obligate intracellular pathogen affecting monocytes and macrophages. Contents 1 2 Symptoms 3 ...

---

★リンクテーブル★

リンク元	「Ehrlichia chaffeensis」
関連記事	「human」「Ehrlichiosis」

「Ehrlichia chaffeensis」

　　[★]

関

human monocytotropic ehrlichiosis

「human」

　　[★]

• n.

• ヒト

• adj.

• ヒトの、ヒト型の

関

ape、hominid、Hominidae、homo、Homo sapiens、human being、human race、human-type、man、Pongidae

　 　 　 　

「Ehrlichiosis」

　　[★]

エーリキア症、エールリヒア症、エールリッヒ症、エールリッヒア症