hormone-producing tumor

• ホルモン産生腫瘍

WordNet

1. the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect (同)endocrine, internal_secretion
2. an abnormal new mass of tissue that serves no purpose (同)tumour, neoplasm

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1. ホルモン

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• 1. 甲状腺ホルモンに対する感受性の低下 reduced sensitivity to thyroid hormone
• 2. 転移性乳癌の全身治療：一般原則 systemic treatment for metastatic breast cancer general principles
• 3. コルチコトロピン-放出ホルモン（CRH）刺激試験 corticotropin releasing hormone stimulation test
• 4. 転移性前立腺癌の初期ホルモン療法 initial hormone therapy for metastatic prostate cancer
• 5. 気管支カルチノイド腫瘍 bronchial carcinoid tumors

English Journal

• High Response Rates and Prolonged Survival in Patients With Corticotroph Pituitary Tumors and Refractory Cushing Disease From Capecitabine and Temozolomide (CAPTEM): A Case Series.

• Zacharia BE1, Gulati AP, Bruce JN, Carminucci AS, Wardlaw SL, Siegelin M, Remotti H, Lignelli A, Fine RL.Author information 1*Department of Neurological Surgery, ‡Experimental Therapeutics Program, Department of Medicine, Division of Medical Oncology, Pancreas Center at Columbia, §Department of Medicine, Neuroendocrine Unit, and ¶Department of Pathology, Herbert Irving Comprehensive Cancer Center, New York Presbyterian Hospital-Columbia University Medical Center, New York, NY.AbstractBACKGROUND AND IMPORTANCE: Rarely, corticotrophic pituitary tumors take on an aggressive form characterized by rapid growth, invasion into local structures, compression of cranial nerves, and possible spread to distant sites. When conventional surgery, radiation therapy, and hormones fail to control progression and symptoms, alternative therapies are needed. A novel chemotherapeutic regimen of capecitabine and temozolomide (CAPTEM), originally designed in our laboratory, demonstrated dramatic antineoplastic effects against corticotrophic pituitary tumors.
• Neurosurgery.Neurosurgery.2014 Apr;74(4):E447-55. doi: 10.1227/NEU.0000000000000251.
• BACKGROUND AND IMPORTANCE: Rarely, corticotrophic pituitary tumors take on an aggressive form characterized by rapid growth, invasion into local structures, compression of cranial nerves, and possible spread to distant sites. When conventional surgery, radiation therapy, and hormones fail to control
• PMID 24226425

• Geometric survey on magnetic resonance imaging of growth hormone producing pituitary adenoma.

• Bakhtiar Y1, Hanaya R, Tokimura H, Hirano H, Oyoshi T, Fujio S, Bohara M, Arita K.Author information 1Department of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1, Sakuragaoka, Kagoshima, 890-8520, Japan.AbstractApart from the radiologic features regarding size and invasiveness, we had noticed some differences in morphology among types of pituitary adenomas. We conducted this study to verify the differences in radiologic morphology between growth hormone producing pituitary adenomas (GHoma) and nonfunctioning pituitary adenomas (NFoma). Pre-surgical magnetic resonance images (MRIs) were assessed in 50 cases of GHoma and 50 cases of NFoma. Geometric parameters on MRI were set in accordance with sellar anatomy. Intensity of T1-weighted image was not different between the two groups, but hypo-intensity of T2-weighted image was more frequently seen in GHoma. Predominant inferior extension of tumor was seen mostly in GHoma (88 vs. 38 %). Extension of the tumor to the superior compartment of cavernous sinus was more frequent in NFoma. Pituitary gland was generally located superior to GHoma and postero-superior to NFoma. Growth characteristics of pituitary adenoma were confirmed to differ between GHoma and NFoma.
• Pituitary.Pituitary.2014 Apr;17(2):142-9. doi: 10.1007/s11102-013-0479-z.
• Apart from the radiologic features regarding size and invasiveness, we had noticed some differences in morphology among types of pituitary adenomas. We conducted this study to verify the differences in radiologic morphology between growth hormone producing pituitary adenomas (GHoma) and nonfunctioni
• PMID 23504370

• Pituitary stem cells: Where do we stand?

• Vankelecom H1, Chen J2.Author information 1Department of Development and Regeneration, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, University of Leuven (KU Leuven), B-3000 Leuven, Belgium. Electronic address: Hugo.Vankelecom@med.kuleuven.be.2Department of Hand Surgery, Tongji Medical College, Union Hospital, Huazhong University of Science & Technology (HUST), Wuhan, Hubei 430022, PR China. Electronic address: chenjianghai2002@hotmail.com.AbstractSome 5years ago, the stem cells of the adult pituitary gland were discovered. Subsequent in-depth characterization revealed expression of several stemness markers and embryo-typical factors. Now, the quest is open to decipher their role in the gland. When and how pituitary stem cells differentiate to contribute to the mature hormone-producing cell populations is not known. New research models support their involvement in cell regeneration after injury in the gland, and suggest a possible role in pituitary tumor formation. From their expression phenotype, pituitary stem cells seem to re-use embryonic developmental programs during the creation of new hormonal cells. Here, we will review the latest progression in the domain of pituitary stem cells, including the uncovering of some new molecular flavors and of the first potential functions. Eventually, we will speculate on their differentiation programs towards hormonal cells, with a particular focus on gonadotropes.
• Molecular and cellular endocrinology.Mol Cell Endocrinol.2014 Mar 25;385(1-2):2-17. doi: 10.1016/j.mce.2013.08.018. Epub 2013 Aug 28.
• Some 5years ago, the stem cells of the adult pituitary gland were discovered. Subsequent in-depth characterization revealed expression of several stemness markers and embryo-typical factors. Now, the quest is open to decipher their role in the gland. When and how pituitary stem cells differentiate t
• PMID 23994027

Japanese Journal

• 症例報告 ホルモン産生腫瘍が疑われ腹腔鏡下手術を施行した1例

• 澁谷 裕美,高木 崇子,綱脇 智法 [他]
• 東京産科婦人科学会会誌 60(4), 594-597, 2011-12
• NAID 40019361848

• GH産生腫瘍の病理学 (特集 先端巨大症診療のUp-to-date)

• 井野元 智恵,長村 義之
• 内分泌・糖尿病・代謝内科 33(3), 174-179, 2011-09
• NAID 40019036614

• 異所性ホルモン産生腫瘍の疾患概念 (内分泌腺腫瘍--基礎・臨床研究のアップデート) -- (異所性ホルモン産生腫瘍)

• 吉本 貴宣,平田 結喜緒
• 日本臨床 69(-) (995), 697-699, 2011-03
• NAID 40018749465

Related Links

• Sex-hormone Producing Tumor | Columbia University ...

The only chance of curing someone with a sex-hormone producing tumor is to completely remove the tumor at the time of surgery. Since these tumors are often cancer and have a risk of spreading to lymph nodes, these operations ...

• Signs and Symptoms of Sex hormone-producing adrenal tumor

Sex hormone-producing adrenal tumor This document is available in Spanish Signs and Symptoms The signs and symptoms of sex-hormone producing tumors can be divided into three categories: Androgen secreting tumors — These ...

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★リンクテーブル★

リンク元	「ホルモン産生腫瘍」
拡張検索	「ectopic growth hormone-releasing hormone-producing tumor」「growth hormone-releasing hormone-producing tumor」「ectopic growth hormone-producing tumor」「gut hormone-producing tumor」「growth hormone-producing tumor」
関連記事	「tumor」

「ホルモン産生腫瘍」

　　[★]

英

hormone-producing tumor, hormone producing tumor

同

機能性腫瘍 functioning tumor、ホルモン活性腫瘍 hormone-active tumor

関

非機能性腫瘍

「ectopic growth hormone-releasing hormone-producing tumor」

　　[★] 異所性成長ホルモン放出ホルモン産生腫瘍

「growth hormone-releasing hormone-producing tumor」

　　[★] 成長ホルモン放出ホルモン産生腫瘍

「ectopic growth hormone-producing tumor」

　　[★] 異所性成長ホルモン産生腫瘍

「gut hormone-producing tumor」

　　[★] 消化管ホルモン産生腫瘍

「growth hormone-producing tumor」

　　[★] 成長ホルモン産生腫瘍

「tumor」

　　[★]

• n.

• 腫瘍、腫瘤、腫脹