- 関
- HBP
WordNet
- a trodden path (同)footpath
- production of a chemical compound by a living organism (同)biogenesis
PrepTutorEJDIC
- 道,小道(path)
UpToDate Contents
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English Journal
- Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle.
- Habegger KM, Penque BA, Sealls W, Tackett L, Bell LN, Blue EK, Gallagher PJ, Sturek M, Alloosh MA, Steinberg HO, Considine RV, Elmendorf JS.SourceDepartment of Cellular and Integrative Physiology, Indiana University School of Medicine, VanNuys Medical Science Building Rm 308A, 635 Barnhill Drive, Indianapolis, IN 46202-5120, USA.
- Diabetologia.Diabetologia.2012 Feb;55(2):457-67. Epub 2011 Oct 15.
- AIMS/HYPOTHESIS: Diminished cortical filamentous actin (F-actin) has been implicated in skeletal muscle insulin resistance, yet the mechanism(s) is unknown. Here we tested the hypothesis that changes in membrane cholesterol could be a causative factor, as organised F-actin structure emanates from ch
- PMID 22002007
- Wnt/β-catenin signaling pathway and thioredoxin-interacting protein (TXNIP) mediate the "glucose sensor" mechanism in metastatic breast cancer-derived cells MDA-MB-231.
- Vaira S, Friday E, Scott K, Conrad S, Turturro F.SourceDepartment of Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
- Journal of cellular physiology.J Cell Physiol.2012 Feb;227(2):578-86. doi: 10.1002/jcp.22757.
- In this study we investigated the effect of glucose on GSK3β and β-catenin expression and the involvement of the N-linked glycosylation and hexosamine pathways in the Wnt canonical pathway in response to in vitro conditions resembling normoglycemia (5 mmol) and hyperglycemia (20 mmol) in the
- PMID 21448924
- Glucose activates free fatty acid receptor 1 gene transcription via phosphatidylinositol-3-kinase-dependent O-GlcNAcylation of pancreas-duodenum homeobox-1.
- Kebede M, Ferdaoussi M, Mancini A, Alquier T, Kulkarni RN, Walker MD, Poitout V.SourceMontreal Diabetes Research Center, Centre de Recherche du Centre Hospitalier de l'Universite de Montreal (CRCHUM), and Departments of Medicine, Nutrition, and Biochemistry, University of Montreal, Montreal, QC, Canada H3T 1J4.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2012 Jan 30. [Epub ahead of print]
- The G protein-coupled free fatty acid receptor-1 (FFA1/GPR40) plays a major role in the regulation of insulin secretion by fatty acids. GPR40 is considered a potential therapeutic target to enhance insulin secretion in type 2 diabetes; however, its mode of regulation is essentially unknown. The aims
- PMID 22308370
Japanese Journal
- Protein O-Glycosylation Induces Collagen Expression and Contributes to Diabetic Cardiomyopathy in Rat Cardiac Fibroblasts
- KOHDA Yuka,KANEMATSU Miwa,KONO Tatsuji,TERASAKI Fumio,TANAKA Takao
- Journal of pharmacological sciences 111(4), 446-450, 2009-12-20
- … In this study, we examined if the hexosamine biosynthesis pathway (HBP) was involved with collagen expression in rat cardiac fibroblasts (RCFs). …
- NAID 10026154906
- Prevention of incipient diabetic cardiomyopathy by high-dose thiamine
- Kohda Yuka,Shirakawa Hisashi,Yamane Kazuhiko,Otsuka Kaoru,Kono Tatsuji,Terasaki Fumio,Tanaka Takao
- The Journal of Toxicological Sciences 33(4), 459-472, 2008-10-01
- … The hexosamine biosynthesis pathway has been implicated in signaling for fibrosis by the kidney. … In this study, we assessed if decrease of flux through the hexosamine biosynthesis pathway induced by high-dose thiamine therapy counteracts diabetes-induced cardiac fibrosis. …
- NAID 110006950525
Related Links
- Nathan DM. Long-term complications of diabetes mellitus. N Engl J Med 1993;328:1676–1685. CrossRef The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development ...
- Abstract Pancreatic exocrine and endocrine cells develop during embryonic life from endodermal progenitors. This process depends on activation of a hierarchy of transcription factors. Although information is available ...
Related Pictures
★リンクテーブル★
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- 関
- HDL-binding protein、hexosamine biosynthesis pathway、high blood pressure、HT、hypertension、hypertensive
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- 英
- hexosamine biosynthesis pathway、HBP
- 関
- 高血圧、HDL結合タンパク質
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- 関
- biogenesis、biogenetic、biosyntheses、biosynthetic
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- 関
- route
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- 関
- biosynthetic pathway