WordNet

lacking interest or significance or impact; "an insipid personality"; "jejune novel" (同)jejune
a polygenic disease characterized by abnormally high glucose levels in the blood; any of several metabolic disorders marked by excessive urination and persistent thirst

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1. 腎性尿崩症の臨床症状および原因 clinical manifestations and causes of nephrogenic diabetes insipidus
2. 腎性尿崩症の治療 treatment of nephrogenic diabetes insipidus
3. 多尿および尿崩症の診断 diagnosis of polyuria and diabetes insipidus
4. 小児における高ナトリウム血症 hypernatremia in children
5. 小児の不明熱に対するアプローチ fever of unknown origin in children evaluation

Azab AN1, Shnaider A, Osher Y, Wang D, Bersudsky Y, Belmaker RH.
International journal of bipolar disorders.Int J Bipolar Disord.2015 Dec;3(1):28. doi: 10.1186/s40345-015-0028-y. Epub 2015 Jun 5.
Reports of toxic effects on the kidney of lithium treatment emerged very soon after lithium therapy was introduced. Lithium-induced nephrogenic diabetes insipidus is usually self-limiting or not clinically dangerous. Some reports of irreversible chronic kidney disease and renal failure were difficul
PMID 26043842

Evidence for the use of demeclocycline in the treatment of hyponatraemia secondary to SIADH: a systematic review.

Miell J1, Dhanjal P2, Jamookeeah C3.
International journal of clinical practice.Int J Clin Pract.2015 Aug 19. doi: 10.1111/ijcp.12713. [Epub ahead of print]
AIMS: Hyponatraemia (HN) is the most common electrolyte balance disorder in clinical practice. Since the 1970s, demeclocycline has been used in some countries to treat chronic HN secondary to syndrome of inappropriate antidiuretic hormone secretion (SIADH). The precise mechanism of action of demeclo
PMID 26289137

Challenges and achievements in the therapeutic modulation of aquaporin functionality.

Beitz E1, Golldack A2, Rothert M2, von Bülow J2.
Pharmacology & therapeutics.Pharmacol Ther.2015 Aug 13. pii: S0163-7258(15)00160-6. doi: 10.1016/j.pharmthera.2015.08.002. [Epub ahead of print]
Aquaporin (AQP) water and solute channels have basic physiological functions throughout the human body. AQP-facilitated water permeability across cell membranes is required for rapid reabsorption of water from pre-urine in the kidneys and for sustained near isosmolar water fluxes e.g. in the brain,
PMID 26277280

Hereditary nephrogenic diabetes insipidus in Japanese patients : analysis of 78 families and report of 22 new mutations in AVPR2 and AQP2

Hemifacial Spasm in Albright's Hereditary Osteodystrophy with Pseudopseudohypoparathyroidism and Nephrogenic Diabetes Insipidus : Case Report

雄山博文,KIDA Yoshihisa,TANAKA Takayuki,IWAKOSHI Takanori,NIWA Masahiro,KITAMURA Ryuuji,KOBAYASHI Tatsuya
Neurologia medico-chirurgica 35(6), 380-384, 1995-06-15
患者は30歳の男性で顔面けいれんを主訴に来院したが, Alblight遺伝性骨異栄養症, 偽性偽性副甲状腺機能低下症, 及び腎性尿崩症も合併していた。脳血管写にて, 年齢の割には著明に蛇行した内頚及び椎骨動脈を認め, 手術時この椎骨動脈本幹が責任血管であることがわかった。我々はこの稀な一例をその病態に関する若干の考察とともに報告する。
NAID 110002278687

大野雅樹,中尾浩二,野末富男,野々村和男,岡部保,豊田桃三
脳と発達 20(1), 23-27, 1988
独歩開始遅延を主訴に来院した男児において, 頭部CTを施行したところ, 偶然脳内石灰化が発見された. 本患児は種々の検査により腎性尿崩症と診断された. 脳内石灰化は両側基底核 (被殻, 淡蒼球) と前頭葉, 後頭葉および頭頂葉皮質にほぼ左右対称性にみられ, 皮質のものは灰白質と白質の境界に存在していた.<BR>脳内石灰化の機序は不明であるが, 原疾患に基づ<高Na, 高浸透圧血症 …
NAID 130004182361