WordNet

a painful inflammation of the big toe and foot caused by defects in uric acid metabolism resulting in deposits of the acid and its salts in the blood and joints (同)gouty_arthritis, urarthritis
suffering from gout

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1. 尿酸による腎疾患 uric acid renal diseases
2. 急性腎障害（急性腎不全）または慢性腎臓病患者に対する診断的アプローチ diagnostic approach to the patient with acute kidney injury acute renal failure or chronic kidney disease
3. 成人における慢性腎臓病マネージメントの概要 overview of the management of chronic kidney disease in adults
4. 急性および慢性腎臓病における高血圧の概要 overview of hypertension in acute and chronic kidney disease
5. 小児における慢性腎臓病のマネージメントの概要 overview of the management of chronic kidney disease in children

Wild-type uromodulin prevents NFkB activation in kidney cells, while mutant uromodulin, causing FJHU nephropathy, does not.

Dinour D1, Ganon L, Nomy LI, Ron R, Holtzman EJ.
Journal of nephrology.J Nephrol.2014 Mar 20. [Epub ahead of print]
BACKGROUND: Uromodulin (Tamm-Horsfall protein) is the most abundant urinary protein in healthy individuals. Despite 60 years of research, its physiological role remains rather elusive. Familial juvenile hyperuricemic nephropathy and medullary cystic kidney disease Type 2 are autosomal dominant tubu
PMID 24648000

El Minshawy O1, Ghabrah T, El Bassuoni E.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.Saudi J Kidney Dis Transpl.2014 Jan;25(1):192-5.
The purpose of this study was to determine the prevalence, etiology and risk factors of treated end-stage renal disease (ESRD) in the region of Tabuk, Saudi Arabia. We studied 460 renal replacement therapy patients through a review of medical records and patient interviews and obtained patient demog
PMID 24434411

The relationship between children kidney diseases and adult ESRD--an epidemiological investigation of 700 cases.

Guo YN1, Wang Z, Lu J.
Renal failure.Ren Fail.2013 Nov;35(10):1353-7. doi: 10.3109/0886022X.2013.828262. Epub 2013 Aug 21.
BACKGROUND: We planned an epidemic investigation of 700 cases who suffered from chronic renal failure (CRF) to search for the evidence to demonstrate the relationship between children kidney diseases and adult CRF.METHODS: Seven hundred patients from four hospitals in Chengdu, China, were investigat
PMID 23964745

Yozinkodakuto, a traditional Chinese (Japanese Kampo) medicine, improves the creatinine level in chronic renal failure

長坂和彦,FUKUDA Hidehiko,HASHIMOTO Masaya,EBE Koji,EBE Yoichiro
和漢医薬学雑誌 24(3), 87-89, 2007
漢方薬は2000年以上前から腎疾患に用いられてきた。しかし,生化学的,病理学的な検討は始まったばかりである。大黄あるいは大黄含有方剤である温脾湯の報告はあるが,これらは腎不全の進行を抑えるだけで,腎機能を改善するわけではない。一方,西洋医学的にはクレメジンや低蛋白食療法などが行われているが,これもクレアチニンを低下するまでには至っていない。今回我々は,血清クレアチニンが1.5mg/dl以上の患者2 …
NAID 110006317187

Effective treatment of Gouty nephropathy induced chronic renal failure with the nourishing the kidney and depressant turbid dampness decoction

Familial juvenile gouty nephropathy: Exclusion of 16p12 from the candidate locus

リンク元	「痛風腎」
関連記事	「gouty」

英: gouty nephropathy, gouty kidney
同: 尿酸塩腎症 urate nephropathy、高尿酸血性腎症 hyperuricemic nephropathy、痛風性腎症、尿酸性腎症 uric acid nephropathy
関: 高尿酸血症

高尿酸血症による腎障害
尿細管障害をきたす。
病理的には間質に尿酸や尿酸一ナトリウム塩の結晶の存在が確認される。これにより間質の閉塞だけでなく炎症反応を惹起する。リンパ球の浸潤、foreign-body giant cell reaction、ついには線維化をきたす。これは腎髄質や腎乳頭で著明である。 (HIM.1809)
GFRはほぼ正常。脳濃縮能の低下、(蛋白尿？) (HIM.1809)