WordNet

a shape that is generated by rotating an ellipse around one of its axes; "it looked like a sphere but on closer examination I saw it was really a spheroid" (同)ellipsoid of revolution
of or relating to spheres or resembling a sphere; "spherical geometry"

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Very low-density lipoprotein (VLDL)-induced signals mediating aldosterone production.

Tsai YY1, Rainey WE2, Bollag WB3,4.
The Journal of endocrinology.J Endocrinol.2017 Feb;232(2):R115-R129. doi: 10.1530/JOE-16-0237. Epub 2016 Dec 2.
Aldosterone, secreted by the adrenal zona glomerulosa, enhances sodium retention, thus increasing blood volume and pressure. Excessive production of aldosterone results in high blood pressure and contributes to cardiovascular and renal disease, stroke and visual loss. Hypertension is also associated
PMID 27913572

Diosgenin-caused changes of the adrenal gland histological parameters in a rat model of the menopause.

Ajdžanović V1, Jarić I2, Miler M2, Filipović B2, Šošić-Jurjević B2, Ristić N2, Milenkovic D3, Milošević V2.
Acta histochemica.Acta Histochem.2017 Jan;119(1):48-56. doi: 10.1016/j.acthis.2016.11.006. Epub 2016 Nov 23.
Diosgenin, a steroidal sapogenin of natural origin, has demonstrated benefits when it comes to the treatment of malignancies, cardiovascular issues and menopausal symptoms. In this study, we investigated the histological changes of the adrenal gland after diosgenin application in a rat model of the
PMID 27889068

Preclinical and Early Clinical Profile of a Highly Selective and Potent Oral Inhibitor of Aldosterone Synthase (CYP11B2).

Bogman K1, Schwab D2, Delporte ML2, Palermo G2, Amrein K2, Mohr S2, De Vera Mudry MC2, Brown MJ2, Ferber P2.
Hypertension (Dallas, Tex. : 1979).Hypertension.2017 Jan;69(1):189-196. Epub 2016 Nov 21.
Primary hyperaldosteronism is a common cause of resistant hypertension. Aldosterone is produced in the adrenal by aldosterone synthase (AS, encoded by the gene CYP11B2). AS shares 93% homology to 11β-hydroxylase (encoded by the gene CYP11B1), responsible for cortisol production. This homology has h
PMID 27872236

Proceedings of the Japan Academy, Series B 90(5), 163-183, 2014
… The adrenal cortex of mammals consists of three concentric zones, i.e., the zona glomerulosa (zG), the zona fasciculata (zF), and the zona reticularis (zR), which secrete mineralocorticoids, glucocorticoids, and adrenal androgens, respectively. …
NAID 130004802296

Activating Transcription Factor 3 (ATF3) in the Human Adrenal Cortex: Its Possible Involvement in Aldosterone Biosynthesis

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The Tohoku Journal of Experimental Medicine 234(4), 249-254, 2014
… ATF3 was immunolocalized to the zona glomerulosa of non-pathological adrenal glands and adrenal glands with IHA, and diffusely detected in the tumor cells of APA and CPA. …
NAID 130004704761

GATA6, SF1, NGFIB and DAX1 in the remodeled subcapsular zones in primary aldosteronism

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Endocrine Journal 61(4), 393-401, 2014
… The results of our immunohistochemical analysis demonstrated the expression levels of 3β-HSD in RSZ of IHA were higher than in RSZ of adjacent adrenals of APA, while those in the zona glomerulosa (ZG) of normal adrenal gland (NA) were in between these two RSZs. …
NAID 130004443948