WordNet
- perform as expected when applied; "The washing machine wont go unless its plugged in"; "Does this old car still run well?"; "This old radio doesnt work anymore" (同)work, operate, go, run
- (mathematics) a mathematical relation such that each element of a given set (the domain of the function) is associated with an element of another set (the range of the function) (同)mathematical function, single-valued function, map, mapping
- a relation such that one thing is dependent on another; "height is a function of age"; "price is a function of supply and demand"
- the actions and activities assigned to or required or expected of a person or group; "the function of a teacher"; "the government must do its part"; "play its role" (同)office, part, role
- what something is used for; "the function of an auger is to bore holes"; "ballet is beautiful but what use is it?" (同)purpose, role, use
- a formal or official social gathering or ceremony; "it was a black-tie function"
- relating to or based on function especially as opposed to structure; "the problem now is not a constitutional one; it is a functional one"; "delegates elected on a functional rather than a geographical basis"
- fit or ready for use or service; "the toaster was still functional even after being dropped"; "the lawnmower is a bit rusty but still usable"; "an operational aircraft"; "the dishwasher is now in working order" (同)usable, useable, operable, operational
- designed for or adapted to a function or use; "functional education selects knowledge that is concrete and usable rather than abstract and theoretical"; "functional architecture"
- designed for or capable of a particular function or use; "a style of writing in which every word is functional"; "functional architecture"
- involving or affecting function rather than physiology; "functional deafness"
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
PrepTutorEJDIC
- (人・物の果たすべき)『働き』,機能,役目;《しばしば複数形で》職務 / (公式の)儀式,《話》大きな催し(集まり),式典 / (数学で)関数 / 〈機械などが〉『機能を果たす』,動く / (…の)役目をする,代用となる《+『as』+『名』》
- 『機能上の』 / (余分なものが無く)機能的な,実用的な / (数学で)関数の
- 蛋白(たんばく)質
UpToDate Contents
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English Journal
- Production of soluble eukaryotic recombinant proteins in E. coli is favoured in early log-phase cultures induced at low temperature.
- San-Miguel T, Pérez-Bermúdez P, Gavidia I.SourceDepartamento de Biología Vegetal, Facultad de Farmacia, Universidad de Valencia, Av. VA Estellés s/n, Burjasot, 46100 Spain.
- SpringerPlus.Springerplus.2013 Dec;2(1):89. Epub 2013 Mar 8.
- BACKGROUND: Producing recombinant plant proteins expressed in Escherichia coli produce in high yields and in a soluble and functional form can be difficult. Under overexpression conditions, proteins frequently accumulate as insoluble aggregates (inclusion bodies) within the producing bacteria. We ev
- PMID 23525091
- Gain of function of immunoglobulins after partial unfolding or cofactor binding.
- Dimitrov JD, Kaveri SV, Lacroix-Desmazes S.SourceCentre de Recherche des Cordeliers, Université Pierre et Marie Curie - Paris6, UMRS 872, Paris, F-75006 France; Université Paris Descartes, UMR S 872, Paris, F-75006 France; INSERM, U872, Paris, F-75006 France. Electronic address: jordan.dimitrov@crc.jussieu.fr.
- Molecular immunology.Mol Immunol.2013 Oct;55(3-4):195-6. doi: 10.1016/j.molimm.2013.03.009. Epub 2013 Apr 9.
- Two recent articles in the Journal of Molecular Biology, provide strong evidence that certain intracellular proteins, mostly involved in the cellular signalling, acquire functional activity only after partial denaturation. Thus, non-native forms of such proteins acquire functional activity, while th
- PMID 23582926
- A unique form of haptoglobin produced by murine hematopoietic cells supports B-cell survival, differentiation and immune response.
- Huntoon KM, Russell L, Tracy E, Barbour KW, Li Q, Shrikant PA, Berger FG, Garrett-Sinha LA, Baumann H.SourceDepartment of Molecular and Cellular Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA.
- Molecular immunology.Mol Immunol.2013 Oct;55(3-4):345-54. doi: 10.1016/j.molimm.2013.03.008. Epub 2013 Mar 30.
- Haptoglobin (Hp), an acute phase reactant and major hemoglobin-binding protein, has a unique role in host immunity. Previously, we demonstrated that Hp-deficient C57BL/6J mice exhibit stunted development of mature T- and B-cells resulting in markedly lower levels of antigen-specific IgG. The current
- PMID 23548836
Japanese Journal
- Long-term Potentiation of Inhibitory Synaptic Transmission onto Cerebellar Purkinje Neurons Contributes to Adaptation of Vestibulo-Ocular Reflex.
- Tanaka Shinsuke,Kawaguchi Shin-Ya,Shioi Go,Hirano Tomoo
- The Journal of neuroscience : the official journal of the Society for Neuroscience 33(43), 17209-17220, 2013-10-23
- … Previous studies demonstrated that binding of GABAA receptor with GABAA receptor-associated protein (GABARAP) is required for RP, and that a peptide that blocks this binding suppresses RP induction. … To address the functional roles of RP, we generated transgenic mice that express this peptide fused to a fluorescent protein selectively in PNs using the PN-specific L7 promoter. …
- NAID 120005342657
- MLL Becomes Functional through Intra-Molecular Interaction Not by Proteolytic Processing.
- Yokoyama Akihiko,Ficara Francesca,Murphy Mark J,Meisel Christian,Hatanaka Chikako,Kitabayashi Issay,Cleary Michael L
- PloS one 8(9), 2013-09-10
- … The mixed lineage leukemia (MLL) protein is an epigenetic transcriptional regulator that controls proliferative expansion of immature hematopoietic progenitors, whose aberrant activation triggers leukemogenesis. … A mature MLL protein is produced by formation of an intra-molecular complex and proteolytic cleavage. …
- NAID 120005333794
- Rap G protein signal in normal and disordered lymphohematopoiesis.
- Minato Nagahiro
- Experimental cell research 319(15), 2323-2328, 2013-09-10
- … The phenotypical studies have unveiled novel, even unexpected functional aspects of Rap signal in cells from a variety of tissues, providing potentially important clues for controlling human diseases, including malignancy. …
- NAID 120005324917
Related Links
- A protein microarray, also known as a protein chip, is a solid surface (typically glass) on which thousands of different proteins (e.g., antigens, antibodies, enzymes, substrates, etc) are immobilized in discrete spatial locations, forming ...
- Jim Quigley explained that proteins that have biological activity can be referred to as functional proteins ... Dairy basics - Calf and Heifer Raising Written by Jim Quigley Originally published: March 1, 2011, in Progressive Dairyman ...
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- Figure 2A shows survival as a function of device removal during index hpspitalization, censored at 1 year or date of last contact. (Figure2Aはは最初の入院中における心臓デバイス除去に関する生存曲線で退院後1年もしくは最後の接触で打ち切っている)
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