WordNet

excitement and elation beyond the bounds of sobriety; "the intoxication of wealth and power"
a blowfish highly prized as a delicacy in Japan but highly dangerous because the skin and organs are poisonous
(British informal) an airless smoky smelly atmosphere

PrepTutorEJDIC

酔い,酩酊(めいてい) / 夢中,陶酔
よどんだ空気,むっとする空気,人いきれ

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1. Cannabis (marijuana): Acute intoxication
2. 合成カンナビノイド：急性中毒 synthetic cannabinoids acute intoxication
3. 覚醒剤：急性中毒 methamphetamine acute intoxication
4. 成人におけるエタノール中毒 ethanol intoxication in adults
5. 小児におけるエタノール中毒：臨床的特徴、評価、およびマネージメント ethanol intoxication in children clinical features evaluation and management

English Journal

Identification of novel genes related to tetrodotoxin intoxication in pufferfish.

Lee JH, Kondo H, Sato S, Akimoto S, Saito T, Kodama M, Watabe S.Author information Laboratory of Aquatic Molecular Biology and Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo, Tokyo 113-8657, Japan.AbstractTo investigate the genes related to the biosynthesis or accumulation of tetrodotoxin (TTX) in pufferfish, mRNA expression patterns in the liver from pufferfish, akamefugu Takifugu chrysops and kusafugu Takifugu niphobles, were compared by mRNA arbitrarily primed reverse transcription-polymerase chain reaction (RAP RT-PCR) with fish bearing different concentrations of TTX and its derivatives. RAP RT-PCR provided a 383 bp cDNA fragment and its transcripts were higher in toxic than non-toxic pufferfish liver. Its deduced amino acid sequence was similar to those of fibrinogen-like proteins reported for other vertebrates. Northern blot analysis and rapid amplification of cDNA ends (RACE) revealed that the cDNA fragment of 383 bp was composed of at least three fibrinogen-like protein (flp) genes, flp-1, flp-2 and flp-3. Relative mRNA levels of flp-1, flp-2 and flp-3 showed a linear correlation with toxicity of the liver for two pufferfish species.
Toxicon : official journal of the International Society on Toxinology.Toxicon.2007 Jun 1;49(7):939-53. Epub 2007 Feb 1.
To investigate the genes related to the biosynthesis or accumulation of tetrodotoxin (TTX) in pufferfish, mRNA expression patterns in the liver from pufferfish, akamefugu Takifugu chrysops and kusafugu Takifugu niphobles, were compared by mRNA arbitrarily primed reverse transcription-polymerase chai
PMID 17360014

[Case of tetrodotoxin intoxication in a uremic patient].

Nakashima R, Nakata Y, Kameoka M, Hayashi N, Watanabe K, Yagi K.Author information Department of Surgery, Division of Emergency and Disaster Medicine, Faculty of Medicine, Tottori University.AbstractIngestion of certain types of puffer fish can result in severe and potentially lethal intoxication, referred to as tetrodotoxin (TTX) intoxication. It is well known that respiratory support plays a key role in the management of patients with TTX intoxication. We describe here the case of a 52-year-old uremic woman, who complained of numbness of the lips and weakness in the legs after ingestion of puffer fish (Lagocephalus wheeleri; called shirosaba-fugu in Japanese). While her symptoms were not severe and she did not require respiratory support, her condition did not improve after 2 days of hospitalization. Hemodialysis was therefore performed on hospital days 3, 4 and 5, and resulted in marked improvement of symptoms. We suggest that the patient's renal dysfunction caused an accumulation of TTX due to delayed excretion and thus modified the clinical course of TTX intoxication. Hemodialysis may be effective in the treatment of TTX intoxication. This is the first report of TTX intoxication in a uremic patient in Japan, and, importantly, the first report of intoxication with Lagocephalus wheeleri, which was previously considered to be a non-toxic species.
Chūdoku kenkyū : Chūdoku Kenkyūkai jun kikanshi = The Japanese journal of toxicology.Chudoku Kenkyu.2007 Apr;20(2):141-5.
Ingestion of certain types of puffer fish can result in severe and potentially lethal intoxication, referred to as tetrodotoxin (TTX) intoxication. It is well known that respiratory support plays a key role in the management of patients with TTX intoxication. We describe here the case of a 52-year-o
PMID 17533966