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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/04 06:35:55」(JST)

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English Journal

  • Contrasting Effects of W781V and W780V Mutations in Helix N of Herpes Simplex Virus 1 and Human Cytomegalovirus DNA Polymerases on Antiviral Drug Susceptibility.
  • Piret J1, Goyette N1, Eckenroth BE2, Drouot E1, Götte M3, Boivin G4.
  • Journal of virology.J Virol.2015 Apr 15;89(8):4636-44. doi: 10.1128/JVI.03360-14. Epub 2015 Feb 11.
  • DNA polymerases of the Herpesviridae and bacteriophage RB69 belong to the α-like DNA polymerase family. In spite of similarities in structure and function, the RB69 enzyme is relatively resistant to foscarnet, requiring the mutation V478W in helix N to promote the closed conformation of the enzyme
  • PMID 25673718
  • Laboratory and clinical aspects of human herpesvirus 6 infections.
  • Agut H1, Bonnafous P2, Gautheret-Dejean A3.
  • Clinical microbiology reviews.Clin Microbiol Rev.2015 Apr;28(2):313-35. doi: 10.1128/CMR.00122-14.
  • Human herpesvirus 6 (HHV-6) is a widespread betaherpesvirus which is genetically related to human cytomegalovirus (HCMV) and now encompasses two different species: HHV-6A and HHV-6B. HHV-6 exhibits a wide cell tropism in vivo and, like other herpesviruses, induces a lifelong latent infection in huma
  • PMID 25762531
  • Characterizing human herpes virus 6 following hematopoietic stem cell transplantation.
  • Perissinotti AJ1, Gulbis A2, Shpall EJ3, Howell J4.
  • Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.J Oncol Pharm Pract.2015 Apr;21(2):85-92. doi: 10.1177/1078155213519837. Epub 2014 Jan 9.
  • BACKGROUND: Human herpes virus 6 reactivation occurs in approximately 50% of patients following hematopoietic stem cell transplant, however, the significance of human herpes virus 6 reactivation remains uncertain.METHODS: A retrospective study was conducted analyzing clinical data of patients testin
  • PMID 24407957

Japanese Journal

  • 抗サイトメガロウイルス薬 (特集 抗ウイルス薬) -- (抗ウイルス薬の特性と適応・使い分け)
  • A fatal case of cytomegalovirus ventriculoencephalitis in a mycosis fungoides patient who received multiple umbilical cord blood cell transplantations
  • Matsukawa Toshihiro,Goto Hideki,Takahashi Kenta,Asanuma Shinsuke,Yasumoto Atsushi,Takahata Mutsumi,Shigematsu Akio,Endo Tomoyuki,Tanaka Junji,Hashino Satoshi,Tanaka Shinya,Imamura Masahiro
  • International Journal of Hematology 95(2), 217-222, 2012-02
  • Foscarnet (FCV) therapy led to a temporary recovery, after which CMV ventriculoencephalitis recurred and the patient died after receiving combination GCV and FCV therapy. …
  • NAID 80022323847
  • Safety of pre-engraftment prophylactic foscarnet administration after allogeneic stem cell transplantation
  • Ishiyama Ken,Katagiri Takamasa,Ohata K.,Hosokawa Kohei,Kondo Yukio,Yamazaki Hirohito,Takami Akiyoshi,Nakao Shinji
  • Transplant Infectious Disease 14(1), 33-39, 2012-02
  • … Because our previous trial of preemptive therapy with foscarnet sodium (phosphonoformic acid; …
  • NAID 120003989051

Related Links

This phosphonic acid derivative (marketed by Clinigen as foscarnet sodium under the trade name Foscavir) is an antiviral medication used to treat herpes viruses, including drug-resistant cytomegalovirus (CMV) and herpes simplex viruses ...
Prescribing information from the National Library of Medicine.

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ホスカルネットナトリウム foscarnet sodiumホスカルネットナトリウム水和物 foscarnet sodium hydrate

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