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(体内にできる)新生物;腫瘍(しゅよう)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/10/03 06:58:04」(JST)

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Fibroepithelial neoplasms (or tumors) are biphasic tumors. This means they consist of epithelial tissue, and stromal or mesenchymal tissue. They may be benign or malignant.^[1]

Examples include:

Brenner tumor of the Ovary
Fibroadenoma of the Breast
Phyllodes tumor of the Breast

External links

derm/346 at eMedicine - "Premalignant Fibroepithelial Tumor"

References

^ Tavassoli, F.A., Devilee, P. (Eds). 2003. World Health Organization Classification of Tumours: Pathology & Genetics: Tumours of the breast and female genital organs. IARC Press: Lyon. ISBN 92-832-2412-4

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UpToDate Contents

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1. 膵管内乳頭粘液性腫瘍（IPMN）：病態生理および臨床症状 intraductal papillary mucinous neoplasm of the pancreas ipmn pathophysiology and clinical manifestations
2. 芽球性形質細胞様樹状細胞腫瘍 blastic plasmacytoid dendritic cell neoplasm
3. Intraductal papillary mucinous neoplasm of the pancreas (IPMN): Evaluation and management
4. 悪性肝腫瘍の病理 pathology of malignant liver tumors
5. 皮下蜂窩織炎様T細胞性リンパ腫の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of subcutaneous panniculitis like t cell lymphoma

English Journal

Unusual benign polypoid and papular neoplasms and tumor-like lesions of the vulva.

Abdullgaffar B1, Keloth TR2, Raman LG3, Mahmood S4, Almulla A5, Almarzouqi M6, Al-Hasani S7.Author information 1Pathology Section, Rashid Hospital, Dubai, UAE. Electronic address: badraah009@yahoo.com.2Histopathology Department, Dubai Hospital, Dubai, UAE.3Histology Unit, Dubai Hospital, Dubai, UAE.4Gynecology Department, Dubai Hospital, Dubai, UAE.5Gynecology Department, AlWasl Hospital, Dubai, UAE.6Pediatrics Surgery, AlWasl Hospital, Dubai, UAE.7Urology Department, Dubai Hospital, Dubai, UAE.AbstractWe aimed to investigate the prevalence and spectrum of unusual benign neoplasms and tumor-like lesions presenting as vulvar polyps and papules, to study their clinical, pathologic, hormonal, and developmental features and whether they have important associations with other pathologic lesions or clinical diseases. We conducted a retrospective review study of 115 vulvar specimens over 7 years. Common lesions, for example, fibroepithelial polyps, skin tags, papillomas, abscesses, viral warts and common cysts, were excluded. We found 21 cases (18%) with uncommon benign vulvar lesions. They included 7 epithelial cysts, 3 vascular lesions, 3 glandular neoplasms, 3 endometrioses, 1 caruncle, 1 pilonidal sinus, 1 prolapsed urethra, 1 seborrheic keratosis, and 1 granular cell tumor. The age range was between 1 and 64 years with a mean age of 33 years. Most (86%) were 2.5 cm or less. Many were asymptomatic incidental pathologic findings that can be missed clinically. Nine cases have important clinical associations or coexisting incidental pathologic lesions. Some lesions demonstrated hormone receptors. Some were clinically confused with fibroepithelial polyps, abscesses, warts, melanocytic lesions, and tumors. In conclusion, although the vulva is a small compartment, its developmental and histologic complexity can result in a variety of unusual and rare benign polypoid and papular lesions, some unique to the vulva, which might present diagnostic challenges to the clinicians and pathologists. In addition, many bear controversy regarding their histogenesis and origin of development in the vulva.
Annals of diagnostic pathology.Ann Diagn Pathol.2014 Apr;18(2):63-70. doi: 10.1016/j.anndiagpath.2013.11.005. Epub 2013 Nov 25.
We aimed to investigate the prevalence and spectrum of unusual benign neoplasms and tumor-like lesions presenting as vulvar polyps and papules, to study their clinical, pathologic, hormonal, and developmental features and whether they have important associations with other pathologic lesions or clin
PMID 24342664

Incidentally Discovered Extensive Squamous Metaplasia within Borderline Phyllodes Tumor: Presentation of a Rare Tumor.

Uğraş N1, Tolunay S, Atalay FO, Gökgöz S.Author information 1Department of Pathology, Uludağ University, Faculty of Medicine, BURSA, TURKEY.AbstractPhyllodes tumors are uncommon biphasic fibroepithelial neoplasms of breast, comprising less than 1% of all breast neoplasms. We therefore aimed to present the case with its microscopic findings. In this article, we report a 59-year-old female admitted to the general surgery department with a rapidly, enlarging, palpable mass in right breast. After histopathological examination, it was diagnosed as borderline phyllodes tumor with extensive squamous metaplasia. Metaplastic changes are infrequent in the stromal and epithelial component of these tumors. Extensive squamous metaplasia within phyllodes tumor is rare and may occur in benign, borderline and malign subtypes.
Turk patoloji dergisi.Turk Patoloji Derg.2014 Feb 27. doi: 10.5146/tjpath.2014.01225. [Epub ahead of print]
Phyllodes tumors are uncommon biphasic fibroepithelial neoplasms of breast, comprising less than 1% of all breast neoplasms. We therefore aimed to present the case with its microscopic findings. In this article, we report a 59-year-old female admitted to the general surgery department with a rapidly
PMID 24585350

Fibroepithelial tumors of the breast: pathologic and immunohistochemical features and molecular mechanisms.

Yang X1, Kandil D, Cosar EF, Khan A.Author information 1From the Department of Pathology, University of Massachusetts Medical School and UMass Memorial Medical Center, Worcester.AbstractCONTEXT: The 2 main prototypes of fibroepithelial tumors of the breast include fibroadenoma and phyllodes tumor (PT). Although both tumors share some overlapping histologic features, there are significant differences in their clinical behavior and management. Phyllodes tumors have been further divided into clinically relevant subtypes, and there is more than one classification scheme for PT currently in use, suggesting a lack of consistency within different practices. Accurate differentiation between fibroadenoma and PT, as well as the grading of PT, may sometimes be challenging on preoperative core needle biopsy. Some immunohistochemical markers have been suggested to aid in the pathologic classification of these lesions.
Archives of pathology & laboratory medicine.Arch Pathol Lab Med.2014 Jan;138(1):25-36. doi: 10.5858/arpa.2012-0443-RA.
CONTEXT: The 2 main prototypes of fibroepithelial tumors of the breast include fibroadenoma and phyllodes tumor (PT). Although both tumors share some overlapping histologic features, there are significant differences in their clinical behavior and management. Phyllodes tumors have been further divid
PMID 24377809