フェロキシダーゼ
- 関
- ceruloplasmin
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/07/21 21:38:12」(JST)
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Ferroxidase |
Identifiers |
EC number |
1.16.3.1 |
CAS number |
9031-37-2 |
Databases |
IntEnz |
IntEnz view |
BRENDA |
BRENDA entry |
ExPASy |
NiceZyme view |
KEGG |
KEGG entry |
MetaCyc |
metabolic pathway |
PRIAM |
profile |
PDB structures |
RCSB PDB PDBe PDBsum |
Gene Ontology |
AmiGO / EGO |
Search |
PMC |
articles |
PubMed |
articles |
NCBI |
proteins |
|
Ferroxidase also known as Fe(II):oxygen oxidoreductase is an enzyme that catalyzes the oxidization of iron II to iron III:
- 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2H2O
Examples
Human genes encoding proteins with ferroxidase activity include:
- CP – Ceruloplasmin
- FTH1 – Ferritin heavy chain
- FTMT – Ferritin, mitochondrial
- HEPH - Hephaestin
References
- Cox JC, Boxer DH (1986). "The role of rusticyanin, a blue copper protein, in the electron transport chain of Thiobacillus ferrooxidans grown on iron or thiosulfate". Biotechnol. Appl. Biochem. 8: 269–275.
- Osaki S (November 1966). "Kinetic studies of ferrous ion oxidation with crystalline human ferroxidase (ceruloplasmin)". J. Biol. Chem. 241 (21): 5053–9. PMID 5925868.
- Osaki S, Walaas O (June 1967). "Kinetic studies of ferrous ion oxidation with crystalline human ferroxidase. II. Rate constants at various steps and formation of a possible enzyme-substrate complex". J. Biol. Chem. 242 (11): 2653–7. PMID 6027241.
UpToDate Contents
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English Journal
- Metabolic stress and inflammatory response in high-yielding, periparturient dairy cows.
- Trevisi E, Amadori M, Cogrossi S, Razzuoli E, Bertoni G.SourceIstituto di Zootecnica, Facoltà di Agraria, Università Cattolica del Sacro Cuore, 29122 Piacenza, Italy.
- Research in veterinary science.Res Vet Sci.2012 Oct;93(2):695-704. Epub 2011 Dec 23.
- Increased disease rates are commonly reported among high-yielding dairy cows in the transition period, extending from 3weeks before to 3weeks after calving, and characterized by the occurrence of an inflammatory response in terms of both positive and negative acute phase proteins (APP+ and APP-). To
- PMID 22197526
- Effect of different levels of copper and molybdenum supplements on serum lipid profiles and antioxidant status in cashmere goats.
- Zhang W, Zhang Y, Zhang SW, Song XZ, Jia ZH, Wang RL.SourceState Key Laboratory for Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
- Biological trace element research.Biol Trace Elem Res.2012 Sep;148(3):309-15. Epub 2012 Mar 10.
- An experiment was conducted to investigate on the effects of different levels of copper (Cu: 0, 19, and 38 mg/kg) and molybdenum (Mo: 0 and 5 mg/kg) supplements and the interaction of these two factors on serum lipid profiles and antioxidant status in cashmere goats during the cashmere fiber growi
- PMID 22407467
Japanese Journal
- Characterization of Glycosylphosphatidylinositol-Anchored Ceruloplasmin Enriched in the Apical Plasma Membrane of Rat Hepatocytes
- Flores Maria Jolina Lou N.,Koyota Souichi,Qiao Zhiwei,Koizumi Yukio,Sugiyama Toshihiro
- 秋田医学 40(3-4), 163-173, 2014-03-31
- … It has been implicated in iron metabolism because of its ferroxidase activity. … Immunoreactive Cp protein was released after incubation with phosphatidylinositol-specific phospholipase C, and the free protein demonstrated ferroxidase activity. …
- NAID 120005441909
- 3P075 ウマLフェリチンサブユニットへの鉄酸化活性部位の導入(01D.蛋白質:機能,ポスター,日本生物物理学会年会第51回(2013年度))
- Nemoto Mai,Harada Tomoaki,Yoshimura Hideyuki
- 生物物理 53(SUPPLEMENT_1-2), S224, 2013-09-13
- NAID 110009819879
- 3P002 二核フェロキシダーゼ中心をもつピロリ菌好中球活性化タンパク質の構造(01A.蛋白質:構造,ポスター,日本生物物理学会年会第51回(2013年度))
- Yokoyama Hideshi,Tsuruta Osamu,Akao Naoya,Fujii Satoshi
- 生物物理 53(SUPPLEMENT_1-2), S212, 2013-09-13
- NAID 110009819806
Related Links
- セルロプラスミン (ceruloplasminまたはcaeruloplasmin)は、公式にはフェロキシダーゼ (ferroxidase)または鉄(II):酸素-オキシドリダクターゼとして知られている。 血液中に 見られる銅輸送タンパクであり、酵素である。(EC 1.16.3.1) ...
Related Pictures
★リンクテーブル★
[★]
- 英
- ceruloplasmin
- ラ
- ceruloplasminum
- 同
- フェロオキシダーゼ ferroxidase
- 関
- 血清銅
- 分子量:132 kDa
- 糖タンパク
- α2グロブリン
- 肝臓で合成
- 銅の運搬に関わる
- 1分子当り6-8原子の銅を含む(臨床検査法提要第32版 p.487)
- 基準値:21-37 mg/dl (臨床検査法提要第32版 p.487)
臨床関連
セルロプラスミン高値
- 感染症、悪性腫瘍(白血病、悪性リンパ腫など)、膠原病(SLE、RAなど)、胆汁うっ滞を伴う肝・胆道疾患など
セルロプラスミン低値
[★]
- 英
- ferroxidase
- 関
- セルロプラスミン